From dd88abe464daecc44151d4f8f527a03b1e282336 Mon Sep 17 00:00:00 2001 From: Maxence Larrieu <m@larri.eu> Date: Mon, 8 Jan 2024 15:43:45 +0100 Subject: [PATCH] UGA RORs added --- 0-collect-data/datacite-dois.txt | 1591 ++++++++------ 0-collect-data/datacite.py | 108 +- 0-collect-data/nakala-dois.txt | 6 +- 0-collect-data/nakala.py | 15 +- 0-collect-data/rdg-dois.txt | 60 +- 0-collect-data/rdg.py | 14 +- .../UGA-ror-childs--2023-12-29--manual.csv | 65 + .../UGA-ror-childs--2023-12-29.csv | 65 + .../ror-retrieve-uga-rors.py | 129 ++ 0-collect-data/zenodo-dois.txt | 1950 +++++++++-------- 0-collect-data/zenodo.py | 9 +- ...ich-dois.py => concatenate-enrich-dois.py} | 25 +- .../z_personal_functions.py | 48 +- 2-produce-graph/hist--datasets-by-year.png | Bin 26070 -> 30174 bytes 2-produce-graph/hist-quantity-by-year.py | 11 +- 2-produce-graph/pie--datacite-client.png | Bin 41047 -> 41386 bytes 2-produce-graph/pie--datacite-type.png | Bin 39886 -> 39358 bytes 2-produce-graph/pie-data-type.py | 3 +- 2-produce-graph/pie-datacite-client.py | 3 +- README.md | 2 +- dois-uga.csv | 467 ++++ run-all-codes.py | 41 +- 22 files changed, 2801 insertions(+), 1811 deletions(-) create mode 100644 0-collect-data/uga-find-ror-childs/UGA-ror-childs--2023-12-29--manual.csv create mode 100644 0-collect-data/uga-find-ror-childs/UGA-ror-childs--2023-12-29.csv create mode 100644 0-collect-data/uga-find-ror-childs/ror-retrieve-uga-rors.py rename 1-enrich-with-datacite/{concatenet-enrich-dois.py => concatenate-enrich-dois.py} (67%) diff --git a/0-collect-data/datacite-dois.txt b/0-collect-data/datacite-dois.txt index 7821df9..1edbc0b 100644 --- a/0-collect-data/datacite-dois.txt +++ b/0-collect-data/datacite-dois.txt @@ -1,730 +1,939 @@ -10.25647/liepp.pb.11 -10.6084/m9.figshare.21430977.v1 -10.34929/xttd-nb60 -10.17178/emaa_hc3n_rotation_4ac6b479 -10.17178/amma-catch.cl.rain_o -10.5061/dryad.4n5929c -10.7280/d1gw91 -10.17178/emaa_c(17o)_hyperfine_0ecc62b5 -10.48537/hal-03220373 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+10.6084/m9.figshare.22625614 +10.6084/m9.figshare.23575363 +10.6084/m9.figshare.21285665 +10.5061/dryad.m7m72 +10.48537/hal-03220254 +10.48537/hal-03220379 +10.6084/m9.figshare.22625620 +10.5281/zenodo.10341149 +10.5061/dryad.n230404 +10.25384/sage.21845348 diff --git a/0-collect-data/datacite.py b/0-collect-data/datacite.py index 1e44d66..9a3adad 100644 --- a/0-collect-data/datacite.py +++ b/0-collect-data/datacite.py @@ -3,28 +3,17 @@ """ -## Documentation -* Doc générale API : https://support.datacite.org/docs/api +## Doc +* datacite API : https://support.datacite.org/docs/api * Recherche d'un DOI : https://support.datacite.org/docs/api-sampling * Pagination : https://support.datacite.org/docs/pagination -> "DataCite added support for affiliation identifiers in Metadata Schema 4.3, released August 2019" +* nb : "DataCite added support for affiliation identifiers in Metadata Schema 4.3, released August 2019" https://support.datacite.org/docs/can-i-see-more-detailed-affiliation-information-in-the-rest-api -* pour descendre au niveau des auteurs -le filtre `?person-id=orcid-nb` +* mémo : pour descendre au niveau des auteurs , le filtre `?person-id=orcid-nb` """ -query_mode = [ - 'creators.affiliation.affiliationIdentifier:"https://ror.org/02rx3b187"', - 'contributors.affiliation.affiliationIdentifier:"https://ror.org/02rx3b187"', - "publisher:(grenoble AND alpes)", # /!\ apporte du text - "client_id:inist.osug", # OSUG https://doi.osug.fr/ - "client_id:jbru.aau", # le laboratoire AAU (architecture) /!\ apporte du text - "client_id:inist.persyval" # Labex Persyval-lab (PIA) - # possibilité d'ajouter d'autres requêtes -] - -def get_results(query_from_list): +def get_results(query_from_list, view_results): """ lance les requêtes dans l'API """ @@ -32,7 +21,7 @@ def get_results(query_from_list): query_root = "https://api.datacite.org/dois?query=" # les type de datasets à exclure (à voir si on retire text) - # nb : en 2023-12-15 ça retire seulement 15 DOIs + # note 2023-12-15 ça retire seulement 15 DOIs query_filter_type = " AND resource_type_id:(-book -bookChapter -conferencePaper -conferenceProceeding -dissertation -event -journal -journalArticle -peerReview -preprint -report -service)" query_page = "&page[size]=100" @@ -40,8 +29,10 @@ def get_results(query_from_list): req = requests.get(query_root + query_from_list + query_filter_type + query_page) results = [req.json()] - # print total dataset per query - print(f"\n\t{req.url}\n\t{results[0]['meta']['total']}") + if view_results: + # print total dataset per query + print(f"\n\t{req.url}") + print(f"\t{results[0]['meta']['total']}") # obtenir les résultats de chaque page dans la liste results nb_pages = results[0]["meta"]["totalPages"] @@ -59,8 +50,7 @@ def get_dois(results): Ajouter les datasets avec DOI dans une liste et identifier ceux sans DOI """ - dois = [] - not_dois = [] + temp_dois = [] # prendre en compte les résultats de chaque page for res in results: @@ -69,37 +59,75 @@ def get_dois(results): for item in num_dois : item_id = item["id"] - # si le dataset a autre chose qu'un DOI - if item.get("type") != "dois": - not_dois.append(item_id) + # si le dataset a un id qui correspond à un DOI + if item.get("type") == "dois": + temp_dois.append(item_id) else: - dois.append(item_id) + ## si l'id n'est pas un DOI on l'ajoute ds une liste globale + main_no_dois.append(item_id) - return dois, not_dois + return temp_dois + + +print("\n\nRunning datacite.py") + +import requests, pandas as pd +main_dois = [] +main_no_dois = [] + +## __________0__________ query with all RORs from UGA on authors and contributors +### load table containing finded ROR +df_raw = pd.read_csv("uga-find-ror-childs/UGA-ror-childs--2023-12-29--manual.csv") +#print("columns name: ", [colname for colname in df_raw.columns]) -# _____0____ récupérer les dois -import requests -dois, not_dois = [], [] +### select accurate ROR +df_hal = df_raw[ df_raw["docid"].notna() ] ## RORs finded via HAL +df_ror = df_raw[ df_raw["Unnamed: 6"] == "include"] ## RORs selected manually /!\ col name +rors = df_hal.ror.tolist() + df_ror.ror.tolist() +rors.append("https://ror.org/02rx3b187") ## add the ROR from UGA ! +print(f"\t__process by ROR\n\tnb of ROR loaded\t{len(rors)}") +# debug : try only with UGA ROR +# rors = ["https://ror.org/02rx3b187"] + +for ror in rors : + for auth_type in ["creators", "contributors"] : + query = f"{auth_type}.affiliation.affiliationIdentifier:\"{ror}\"" + temp_doi_list = get_dois(get_results(query, False)) + [main_dois.append(elem) for elem in temp_doi_list] + +print(f"\tnb DOIs finded \t{len(main_dois)}") + + +## __________1__________ query by datacite client and UGA as pupublisher +print(f"\n\t__process by datacite clients") +query_client_publisher = [ + "client_id:inist.osug", # OSUG https://doi.osug.fr/ + "client_id:inist.persyval", # Labex Persyval-lab (PIA) + "client_id:jbru.aau", # le laboratoire AAU (architecture) /!\ apporte du text + "publisher:(grenoble AND alpes)" # /!\ apporte du text + # add your query here +] -for query in query_mode: - doi, not_doi = get_dois(get_results(query)) - dois += doi - not_dois += not_doi +for query in query_client_publisher: + temp_doi_list = get_dois(get_results(query, True)) + [main_dois.append(elem) for elem in temp_doi_list] +print(f"\tnb DOI finded \t{len(main_dois)}") -if not_doi : - print("Des données avec un autre identifiant que le DOI ont été trouvées") - [print(f"\t\t{item_id}") for item_id in not_doi] +## __________n__________ if Datasets with other things that a DOI have been finded +if main_no_dois : + print("datasets with an other identifier than DOI has been finded") + [print(f"\t\t{elem}") for elem in main_no_dois] -# _____n____ remove duplicates in DOI list -unique_dois = list(set(dois)) -print(f"Nb unique DOI\t{len(unique_dois)}") +## __________n__________ remove duplicates +unique_dois = list(set(main_dois)) +print(f"\tNb of unique DOI\t{len(unique_dois)}") -# _____z____ exporter liste DOI format txt +# __________z__________ export DOIs in txt files with open("datacite-dois.txt", 'w') as f : [f.write(f"{line}\n") for line in unique_dois] diff --git a/0-collect-data/nakala-dois.txt b/0-collect-data/nakala-dois.txt index a65bea5..e5fa703 100644 --- a/0-collect-data/nakala-dois.txt +++ b/0-collect-data/nakala-dois.txt @@ -8,8 +8,8 @@ 10.34847/nkl.748eqz51 10.34847/nkl.2c0fj3ai 10.34847/nkl.2bad8uj6 -10.34847/nkl.87788ro3 10.34847/nkl.2404plkh +10.34847/nkl.87788ro3 10.34847/nkl.bafagy29 10.34847/nkl.9bd4vqc6 10.34847/nkl.4540o25d @@ -22,8 +22,8 @@ 10.34847/nkl.3dbc2mtb 10.34847/nkl.bc2b1071 10.34847/nkl.81dcdekj -10.34847/nkl.b1cb3arm -10.34847/nkl.c9e92or4 +10.34847/nkl.ef903o6v +10.34847/nkl.ae94a74k 10.34847/nkl.bf5f263z 10.34847/nkl.9f85iol5 10.34847/nkl.345bf9i7 diff --git a/0-collect-data/nakala.py b/0-collect-data/nakala.py index 74cc96b..6c75cf6 100644 --- a/0-collect-data/nakala.py +++ b/0-collect-data/nakala.py @@ -68,17 +68,20 @@ def get_dois_n_users(user_id): import json, requests +print("\n\nRunning nakala.py") + + ## list to stock datas nakala_uga_users = [] all_dois = [] other_user_finded = [] -## importer les users depuis le fichier txt +## load nakala users from txt file with open('nakala-uga-users.txt', 'r') as f: ## attention bien stripper quand on import du txt sinon les sauts de ligne sont présents [nakala_uga_users.append( user.strip() ) for user in f.readlines()] -print("nb d'utilisateur Nakala UGA importés", len(nakala_uga_users)) +print("\tnb nakala users loaded", len(nakala_uga_users)) # ____n____ iterer sur les users uga for user in nakala_uga_users : @@ -87,7 +90,7 @@ for user in nakala_uga_users : res = get_dois_n_users(user) if res["continue"] : - print(f"{user}\n\tnb DOI {len(res['content'])}" ) + #print(f"{user}\n\tnb DOI {len(res['content'])}" ) ## ajouter les DOIs trouvés if len(res["content"]) > 0 : @@ -98,6 +101,8 @@ for user in nakala_uga_users : #print(f"\nnew person {','.join(res['other_users'])}") other_user_finded += [x for x in res["other_users"] ] +print(f"\tnb dois finded\t\t{len(all_dois)}") + ## ____n____ exporter les DOI au format txt @@ -106,7 +111,7 @@ with open("nakala-dois.txt", 'w') as fh : ## print les autres utilisateurs trouvés if other_user_finded : - print("\n\n nakala new user finded ") + print("\n\n\tnakala new user finded ") for elem in other_user_finded : - print(f"\t\t{elem}") + print(f"\t\t\t{elem}") diff --git a/0-collect-data/rdg-dois.txt b/0-collect-data/rdg-dois.txt index f997813..ae4c193 100644 --- a/0-collect-data/rdg-dois.txt +++ b/0-collect-data/rdg-dois.txt @@ -1,42 +1,42 @@ -10.57745/52HT2L -10.57745/7RFNNP +10.57745/QCVYG3 +10.57745/LPJ2S2 +10.57745/5O6QIH 10.57745/UOGRPY -10.57745/GRHRZJ -10.57745/7HF7KG +10.57745/Z3BG2U +10.57745/ID1LS6 +10.57745/3D4DFW 10.57745/ENJADK +10.57745/LUTMNE 10.57745/69UNAM -10.57745/NZFWP9 +10.57745/GZKUZS +10.57745/QOA1QO 10.57745/R1NIKK -10.57745/QCVYG3 10.57745/KTFZQD -10.57745/B6PSX0 -10.15454/M7OK9E -10.57745/CM2WOI -10.57745/GZKUZS -10.57745/NGC4J0 -10.57745/IZHDPC -10.57745/LPJ2S2 -10.57745/W9N5Z9 -10.57745/TVAHUQ 10.57745/BYWEA3 10.15454/O93984 -10.57745/QOA1QO -10.57745/YWBDQQ 10.57745/JOZ1NA -10.57745/XHQ7TL -10.57745/ID1LS6 +10.57745/HZDPTT +10.57745/W9N5Z9 +10.57745/7RFNNP +10.57745/GRHRZJ 10.57745/3VMB3Y -10.57745/MXEMI4 -10.57745/NOHRHJ -10.57745/OVCWQN -10.57745/5O6QIH +10.57745/CM2WOI +10.57745/XHQ7TL 10.57745/RUQLJL -10.57745/OT1IFB -10.57745/Z3BG2U -10.57745/3D4DFW -10.57745/LXTWNG -10.57745/LUTMNE +10.57745/B6PSX0 +10.57745/NZFWP9 +10.57745/J2A44Q +10.57745/YWBDQQ +10.57745/NOHRHJ 10.15454/8UIA76 +10.57745/OVCWQN +10.57745/IZHDPC 10.57745/TOR3SF -10.57745/J2A44Q -10.57745/HZDPTT +10.57745/LXTWNG +10.57745/NGC4J0 +10.57745/7HF7KG +10.15454/M7OK9E +10.57745/52HT2L +10.57745/MXEMI4 +10.57745/OT1IFB +10.57745/TVAHUQ diff --git a/0-collect-data/rdg.py b/0-collect-data/rdg.py index 78fac16..3a8862c 100644 --- a/0-collect-data/rdg.py +++ b/0-collect-data/rdg.py @@ -2,9 +2,6 @@ ## 2023-12-01, Elias Chetouane """ -## todo -/ - ## Documentation * Noms des champs à requêter : https://entrepot.recherche.data.gouv.fr/api/metadatablocks/citation * Doc API Dataverse : https://guides.dataverse.org/en/5.12.1/api/search.html @@ -34,6 +31,7 @@ urls = [ # on définit une fonction pour la lancer la requete avec chaque url pour les différentes affiliations def get_results(url): req = requests.get(url) + #print(req.url) results = [req.json()] # obtenir les résultats de chaque page dans la liste results @@ -63,11 +61,12 @@ def get_dois(results): for item in num_dois : dois.append(item["global_id"]) - print("Nombre de résultats trouvés : " + str(nb_dois)) + print("\tnb DOIs\t\t" + str(nb_dois)) return dois -# on récupère les dois +print("\n\nRunning rdg.py") +# on récupère les dois dois = [] for url in urls: @@ -77,10 +76,11 @@ for url in urls: unique_dois = list(set(dois)) -print("Nombre de dois différents trouvés : " + str(len(unique_dois))) +print("\tnb DOIs uniques\t\t" + str(len(unique_dois))) # exporter la liste de DOI au format txt with open("rdg-dois.txt", 'w') as f : - [f.write(f"{line[4:]}\n") for line in unique_dois] # [4:] pour retirer "doi:" au début de chaque ligne + # memo [4:] pour retirer "doi:" au début de chaque lignes + [f.write(f"{line[4:]}\n") for line in unique_dois] diff --git a/0-collect-data/uga-find-ror-childs/UGA-ror-childs--2023-12-29--manual.csv b/0-collect-data/uga-find-ror-childs/UGA-ror-childs--2023-12-29--manual.csv new file mode 100644 index 0000000..8af0499 --- /dev/null +++ b/0-collect-data/uga-find-ror-childs/UGA-ror-childs--2023-12-29--manual.csv @@ -0,0 +1,65 @@ +ror,name,type,docid,hal_child_nb,ror_relation_nb,, +https://ror.org/05588ks88,LInguistique et DIdactique des Langues Étrangères et Maternelles,laboratory,1043147,0.0,,, +https://ror.org/01yxtfe92,École nationale supérieure d'architecture de Grenoble,institution,1043352,1.0,,, +https://ror.org/05hz99a17,"Ambiances, Architectures, Urbanités",laboratory,1088635,0.0,,, +https://ror.org/0509qp208,Centre d'études et de recherches appliquées à la gestion,laboratory,1043181,0.0,,, +https://ror.org/05sbt2524,Institut polytechnique de Grenoble - Grenoble Institute of Technology,institution,1043329,15.0,,, +https://ror.org/02z8yps18,"Laboratoire de Génie des Procédés pour la Bioraffinerie, les Matériaux Bio-sourcés et l'Impression Fonctionnelle",laboratory,1162332,0.0,,, +https://ror.org/04eg25g76,Laboratoire de Conception et d'Intégration des Systèmes,laboratory,1043068,0.0,,, +https://ror.org/02wrme198,Grenoble Images Parole Signal Automatique,laboratory,1043333,0.0,,, +https://ror.org/043pfpy19,Laboratoire des Écoulements Géophysiques et Industriels [Grenoble],laboratory,1043048,0.0,,, +https://ror.org/03985kf35,Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525,laboratory,1043049,0.0,,, +https://ror.org/03bcdsr62,"Laboratoire sols, solides, structures - risques [Grenoble]",laboratory,1043064,0.0,,, +https://ror.org/04dbzz632,Institut Néel,laboratory,1043183,0.0,,, +https://ror.org/05hyx5a17,Laboratoire de Génie Electrique de Grenoble,laboratory,1043220,0.0,,, +https://ror.org/01c8rcg82,Laboratoire d'Informatique de Grenoble,laboratory,1043301,0.0,,, +https://ror.org/05afmzm11,VERIMAG,laboratory,1043148,0.0,,, +https://ror.org/04ett5b41,Laboratoire Jean Kuntzmann,laboratory,1043077,0.0,,, +https://ror.org/03taa9n66,"Institut de Microélectronique, Electromagnétisme et Photonique - Laboratoire d'Hyperfréquences et Caractérisation",laboratory,1043224,0.0,,, +https://ror.org/03f0apy98,Laboratoire de Physique Subatomique et de Cosmologie,laboratory,1043144,0.0,,, +https://ror.org/00fwjkb59,Laboratoire d'Economie Appliquée de Grenoble,laboratory,1043256,0.0,,, +https://ror.org/04axb9j69,Laboratoire d'Electrochimie et de Physico-chimie des Matériaux et des Interfaces,laboratory,1043074,0.0,,, +https://ror.org/04as3rk94,[GIN] Grenoble Institut des Neurosciences,regrouplaboratory,408885,0.0,,, +https://ror.org/05rwrfh97,Institut Fourier,laboratory,1043234,0.0,,, +https://ror.org/036zswm25,Laboratoire des technologies de la microélectronique,laboratory,1043042,0.0,,, +https://ror.org/023n9q531,Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères],laboratory,1043294,0.0,,, +https://ror.org/026j45x50,"Pacte, Laboratoire de sciences sociales",laboratory,1043180,0.0,,, +https://ror.org/02mc6qk71,Laboratoire de physique et modélisation des milieux condensés,laboratory,1043152,0.0,,, +https://ror.org/04szabx38,Institut de biologie structurale,department,1043235,0.0,,, +https://ror.org/02dpnb389,Clinatec - Centre de recherche biomédicale Edmond J.Safra,department,416269,0.0,,, +https://ror.org/03x1z2w73,Laboratoire d'Ecologie Alpine,laboratory,1043062,0.0,,, +https://ror.org/045ktmd28,Laboratoire national des champs magnétiques intenses - Grenoble,laboratory,1043255,0.0,,, +https://ror.org/04qz4qy85,LAboratoire de Recherche Historique Rhône-Alpes - UMR5190,laboratory,1043116,0.0,,, +https://ror.org/041rhpw39,Centre Hospitalier Universitaire de Grenoble,healthcare,,,4.0,include, +https://ror.org/000tdrn36,Centre Interuniversitaire de MicroElectronique et Nanotechnologies,facility,,,2.0,include, +https://ror.org/02wmc6m46,Institut d'Histoire des Représentations et des Idées dans les Modernités,facility,,,6.0,error,old UMR +https://ror.org/01cf2sz15,Institut des Sciences de la Terre,facility,,,5.0,include, +https://ror.org/01wwcfa26,Institute of Environmental Geosciences,facility,,,5.0,include, +https://ror.org/03eqm6y13,LabEx PERSYVAL-Lab,facility,,,5.0,include, +https://ror.org/0157h5t87,"Langages, Littératures, Sociétés. Études Transfrontalières et Internationales",facility,,,2.0,error,old UMR +https://ror.org/02f7wz369,Pierre Mendès-France University,education,,,7.0,include, +https://ror.org/03yppfm65,Stendhal University,education,,,5.0,include, +https://ror.org/02rmwrd87,"Laboratoire Environnements, Dynamiques et Territoires de Montagne",facility,,,4.0,include, +https://ror.org/047p7mf25,Institut Carnot PolyNat,facility,,,2.0,include, +https://ror.org/03vte9x46,Observatoire des Sciences de l'Univers de Grenoble,education,,,5.0,include, +https://ror.org/05c99vk74,Laboratoire de Recherche sur les Apprentissages en Contexte,facility,,,2.0,include, +https://ror.org/04fhvpc68,Département de Pharmacochimie Moléculaire,facility,,,2.0,include, +https://ror.org/03jrb0276,"Laboratoire Inter-universitaire de Psychologie: Personnalité, Cognition, Changement Social",facility,,,2.0,include, +https://ror.org/01kbr1737,PHotonique ELectronique et Ingénierie QuantiqueS,facility,,,2.0,include, +https://ror.org/00ndvqf03,Laboratoire Modélisation et Exploration des Matériaux,facility,,,2.0,include, +https://ror.org/0467x8h16,Maison des Sciences de l'Homme-Alpes,facility,,,2.0,include, +https://ror.org/02cmt9z73,Agence pour les Mathématiques en Interaction avec l'Entreprise et la Société,facility,,,2.0,exclude,GDR national +https://ror.org/026m44z54,Laboratoire Nanotechnologies et Nanosystèmes,facility,,,6.0,include, +https://ror.org/03949e763,Integrated Structural Biology Grenoble,facility,,,3.0,include, +https://ror.org/04ndt7n58,"Centre d'Etudes et de Recherche sur la diplomatie, l’Administration Publique et le Politique",facility,,,2.0,include, +https://ror.org/044cfnj78,GRIDCAD - Grenoble Alpes Recherche-Infrastructure de Calcul intensif et de Données,facility,,,4.0,include, +https://ror.org/03e044190,Spintronique et Technologie des Composants,facility,,,4.0,include, +https://ror.org/05hb8m595,PHOTOSYNTHESE,other,,,12.0,exclude,GDR national +https://ror.org/01w1erp60,Couplage Multi-physiques et Multi-échelles en mécanique géo-environnemental,other,,,19.0,exclude,GDR national +https://ror.org/05be9p317,Micropesanteur Fondamentale et Appliquée,other,,,14.0,exclude,GDR national +https://ror.org/01x6z5t49,Fédération de Recherche Spectroscopies de Photoémission,other,,,42.0,exclude,FR national +https://ror.org/01nrtdp55,GDR NBODY : Problème quantique à N corps en chimie et physique,facility,,,38.0,exclude,GDR national +https://ror.org/00hgbrg14,"Fédération française Matériaux sous hautes vitesses de déformation. Application aux matériaux en conditions extrêmes, Procédés et structures",other,,,16.0,exclude,FR national +https://ror.org/0459fdx51,Fédération de Recherche sur l'Energie Solaire,other,,,45.0,exclude,FR national +https://ror.org/04yem5s35,INFRANALYTICS,other,,,16.0,exclude,IR national +https://ror.org/01sgwka45,Microscopie Fonctionnelle du Vivant,facility,,,31.0,exclude,GDR national diff --git a/0-collect-data/uga-find-ror-childs/UGA-ror-childs--2023-12-29.csv b/0-collect-data/uga-find-ror-childs/UGA-ror-childs--2023-12-29.csv new file mode 100644 index 0000000..7ecab27 --- /dev/null +++ b/0-collect-data/uga-find-ror-childs/UGA-ror-childs--2023-12-29.csv @@ -0,0 +1,65 @@ +ror,name,type,docid,hal_child_nb,ror_relation_nb +https://ror.org/05588ks88,LInguistique et DIdactique des Langues Étrangères et Maternelles,laboratory,1043147,0.0, +https://ror.org/01yxtfe92,École nationale supérieure d'architecture de Grenoble,institution,1043352,1.0, +https://ror.org/05hz99a17,"Ambiances, Architectures, Urbanités",laboratory,1088635,0.0, +https://ror.org/0509qp208,Centre d'études et de recherches appliquées à la gestion,laboratory,1043181,0.0, +https://ror.org/05sbt2524,Institut polytechnique de Grenoble - Grenoble Institute of Technology,institution,1043329,15.0, +https://ror.org/02z8yps18,"Laboratoire de Génie des Procédés pour la Bioraffinerie, les Matériaux Bio-sourcés et l'Impression Fonctionnelle",laboratory,1162332,0.0, +https://ror.org/04eg25g76,Laboratoire de Conception et d'Intégration des Systèmes,laboratory,1043068,0.0, +https://ror.org/02wrme198,Grenoble Images Parole Signal Automatique,laboratory,1043333,0.0, +https://ror.org/043pfpy19,Laboratoire des Écoulements Géophysiques et Industriels [Grenoble],laboratory,1043048,0.0, +https://ror.org/03985kf35,Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525,laboratory,1043049,0.0, +https://ror.org/03bcdsr62,"Laboratoire sols, solides, structures - risques [Grenoble]",laboratory,1043064,0.0, +https://ror.org/04dbzz632,Institut Néel,laboratory,1043183,0.0, +https://ror.org/05hyx5a17,Laboratoire de Génie Electrique de Grenoble,laboratory,1043220,0.0, +https://ror.org/01c8rcg82,Laboratoire d'Informatique de Grenoble,laboratory,1043301,0.0, +https://ror.org/05afmzm11,VERIMAG,laboratory,1043148,0.0, +https://ror.org/04ett5b41,Laboratoire Jean Kuntzmann,laboratory,1043077,0.0, +https://ror.org/03taa9n66,"Institut de Microélectronique, Electromagnétisme et Photonique - Laboratoire d'Hyperfréquences et Caractérisation",laboratory,1043224,0.0, +https://ror.org/03f0apy98,Laboratoire de Physique Subatomique et de Cosmologie,laboratory,1043144,0.0, +https://ror.org/00fwjkb59,Laboratoire d'Economie Appliquée de Grenoble,laboratory,1043256,0.0, +https://ror.org/04axb9j69,Laboratoire d'Electrochimie et de Physico-chimie des Matériaux et des Interfaces,laboratory,1043074,0.0, +https://ror.org/04as3rk94,[GIN] Grenoble Institut des Neurosciences,regrouplaboratory,408885,0.0, +https://ror.org/036zswm25,Laboratoire des technologies de la microélectronique,laboratory,1043042,0.0, +https://ror.org/05rwrfh97,Institut Fourier,laboratory,1043234,0.0, +https://ror.org/026j45x50,"Pacte, Laboratoire de sciences sociales",laboratory,1043180,0.0, +https://ror.org/023n9q531,Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères],laboratory,1043294,0.0, +https://ror.org/04szabx38,Institut de biologie structurale,department,1043235,0.0, +https://ror.org/02mc6qk71,Laboratoire de physique et modélisation des milieux condensés,laboratory,1043152,0.0, +https://ror.org/02dpnb389,Clinatec - Centre de recherche biomédicale Edmond J.Safra,department,416269,0.0, +https://ror.org/03x1z2w73,Laboratoire d'Ecologie Alpine,laboratory,1043062,0.0, +https://ror.org/045ktmd28,Laboratoire national des champs magnétiques intenses - Grenoble,laboratory,1043255,0.0, +https://ror.org/04qz4qy85,LAboratoire de Recherche Historique Rhône-Alpes - UMR5190,laboratory,1043116,0.0, +https://ror.org/041rhpw39,Centre Hospitalier Universitaire de Grenoble,healthcare,,,4.0 +https://ror.org/000tdrn36,Centre Interuniversitaire de MicroElectronique et Nanotechnologies,facility,,,2.0 +https://ror.org/02wmc6m46,Institut d'Histoire des Représentations et des Idées dans les Modernités,facility,,,6.0 +https://ror.org/01cf2sz15,Institut des Sciences de la Terre,facility,,,5.0 +https://ror.org/01wwcfa26,Institute of Environmental Geosciences,facility,,,5.0 +https://ror.org/03eqm6y13,LabEx PERSYVAL-Lab,facility,,,5.0 +https://ror.org/0157h5t87,"Langages, Littératures, Sociétés. Études Transfrontalières et Internationales",facility,,,2.0 +https://ror.org/02f7wz369,Pierre Mendès-France University,education,,,7.0 +https://ror.org/03yppfm65,Stendhal University,education,,,5.0 +https://ror.org/02rmwrd87,"Laboratoire Environnements, Dynamiques et Territoires de Montagne",facility,,,4.0 +https://ror.org/047p7mf25,Institut Carnot PolyNat,facility,,,2.0 +https://ror.org/03vte9x46,Observatoire des Sciences de l'Univers de Grenoble,education,,,5.0 +https://ror.org/05c99vk74,Laboratoire de Recherche sur les Apprentissages en Contexte,facility,,,2.0 +https://ror.org/04fhvpc68,Département de Pharmacochimie Moléculaire,facility,,,2.0 +https://ror.org/03jrb0276,"Laboratoire Inter-universitaire de Psychologie: Personnalité, Cognition, Changement Social",facility,,,2.0 +https://ror.org/01kbr1737,PHotonique ELectronique et Ingénierie QuantiqueS,facility,,,2.0 +https://ror.org/00ndvqf03,Laboratoire Modélisation et Exploration des Matériaux,facility,,,2.0 +https://ror.org/0467x8h16,Maison des Sciences de l'Homme-Alpes,facility,,,2.0 +https://ror.org/02cmt9z73,Agence pour les Mathématiques en Interaction avec l'Entreprise et la Société,facility,,,2.0 +https://ror.org/026m44z54,Laboratoire Nanotechnologies et Nanosystèmes,facility,,,6.0 +https://ror.org/03949e763,Integrated Structural Biology Grenoble,facility,,,3.0 +https://ror.org/04ndt7n58,"Centre d'Etudes et de Recherche sur la diplomatie, l’Administration Publique et le Politique",facility,,,2.0 +https://ror.org/044cfnj78,GRIDCAD - Grenoble Alpes Recherche-Infrastructure de Calcul intensif et de Données,facility,,,4.0 +https://ror.org/03e044190,Spintronique et Technologie des Composants,facility,,,4.0 +https://ror.org/05hb8m595,PHOTOSYNTHESE,other,,,12.0 +https://ror.org/01w1erp60,Couplage Multi-physiques et Multi-échelles en mécanique géo-environnemental,other,,,19.0 +https://ror.org/05be9p317,Micropesanteur Fondamentale et Appliquée,other,,,14.0 +https://ror.org/01x6z5t49,Fédération de Recherche Spectroscopies de Photoémission,other,,,42.0 +https://ror.org/01nrtdp55,GDR NBODY : Problème quantique à N corps en chimie et physique,facility,,,38.0 +https://ror.org/00hgbrg14,"Fédération française Matériaux sous hautes vitesses de déformation. Application aux matériaux en conditions extrêmes, Procédés et structures",other,,,16.0 +https://ror.org/0459fdx51,Fédération de Recherche sur l'Energie Solaire,other,,,45.0 +https://ror.org/04yem5s35,INFRANALYTICS,other,,,16.0 +https://ror.org/01sgwka45,Microscopie Fonctionnelle du Vivant,facility,,,31.0 diff --git a/0-collect-data/uga-find-ror-childs/ror-retrieve-uga-rors.py b/0-collect-data/uga-find-ror-childs/ror-retrieve-uga-rors.py new file mode 100644 index 0000000..91679af --- /dev/null +++ b/0-collect-data/uga-find-ror-childs/ror-retrieve-uga-rors.py @@ -0,0 +1,129 @@ +# Récupérer les RORs de l'env. UGA +## 2024-01-08, Maxence Larrieu + + +""" +## step +- recupere les ROR qui ont pour parent le ROR de l'UGA +- HAL : on réduit aux structures VALID +- ROR apporte du bruit et demande un nettoyage manuel a posteriori +- ROR : on retire les UMR passées et les réseaux nationaux type GDR, FR, IR +- cette dernière étape se fait à la main à partir des tableaux produits + + +## documentation + +* HAL +https://api.archives-ouvertes.fr/ref/structure/?q=parentRor_id:02rx3b187 + + +* ROR +https://ror.readme.io/docs/ror-schema-api-v2-beta +https://api.dev.ror.org/v2/organizations/02rx3b187 +""" + + +import requests, json, pandas as pd +import datetime + + +## ___0____ from HAL structure API get UGA ROR childs + +def hal_struct_return_docs(ror_id) : + """ + HAL structure referentiel + https://api.archives-ouvertes.fr/docs/ref/?resource=structure&schema=fields#fields + list structures who have a parent corresponding to ror_id + output raw results inside the "docs" key + """ + + # query human language : childs of ROR structure that are VALID and has a ROR id + req_filter = f"q=parentRor_id:{ror_id}&fq=ror_s:[%22%22%20TO%20*]\ + &fq=valid_s:VALID&fl=ror_s,name_s,type_s,docid" + + req = requests.get("https://api.archives-ouvertes.fr/ref/structure/?" + req_filter + "&rows=500") + # to debug print(req.url) + res = req.json() + return res["response"]["docs"] + + +def hal_struct_return_ror_childs(ror_id) : + """ + boucle récursive + à partir d'un résultat de HAL structure sur parent_ror + itérer sur chacun des éléments et les ajouter + et refaire pareil sur ces éléments + """ + hal_results = hal_struct_return_docs(ror_id) + + for item in hal_results : + # in HAL structure API, ror are in list + for ror_url in item["ror_s"] : + + ## find number of ROR child to the sub element + ror_id = convert_ror_url_to_id(ror_url) + new_hal_results = hal_struct_return_docs(ror_id) + nb_childs = len(new_hal_results) + struct_info = [ror_url, item["name_s"], item["type_s"], item["docid"], nb_childs] + + ror_childs.append(struct_info) + + ## if sub element has ROR child lets iterate on these new results + if nb_childs > 0 : + new_ror_id = convert_ror_url_to_id(ror_url) + hal_struct_return_ror_childs(new_ror_id) + + +def convert_ror_url_to_id (ror_url) : + # convert https://ror.org/05rwrfh97 to 05rwrfh97 + ## car l'API de HAL renoie l'URL pour ces deux champs ror_s et ror_urls :/ + return ror_url[ ror_url.rfind("/") +1 :] + + +ror_childs = [] +hal_struct_return_ror_childs("02rx3b187") + +print(f"from HAL, nb of childs raw\t{len(ror_childs)}") + +df_hal = pd.DataFrame(ror_childs, columns = ["ror", "name", "type", "docid", "hal_child_nb"]) +df_hal.drop_duplicates(subset = ["ror"], inplace = True) +print(f"from HAL, nb of unique childs\t{len(df_hal)}") + + +## ____2____ from ROR API get UGA ROR childs + +def ror_get_child_info(ror_id) : + req = requests.get("https://api.dev.ror.org/v2/organizations/" + ror_id) + res = req.json() + types_list = [ item for item in res["types"]] + org_type = ",".join(types_list) + return { + "org_type" : org_type, + "relation_nb" : len(res["relationships"]) + } + +# query on ROR w UGA ROR_id +req = requests.get("https://api.dev.ror.org/v2/organizations/02rx3b187") +res = req.json() +# relationships contains all ror "childs" +ror_list = res["relationships"] +print(f"from ROR, nb of childs finded\t{len(ror_list)}") + +## for each ROR finded enrich with ROR API +data_from_rors = [] +for item in ror_list : + if item["id"] not in df_hal.ror.values : + org_info = ror_get_child_info(item["id"]) + data_from_rors.append( + [ item["id"], item["label"], org_info["org_type"], org_info["relation_nb"] ] + ) + + +df_ror = pd.DataFrame(data_from_rors, columns = ["ror", "name", "type", "ror_relation_nb"]) + +df = pd.concat([df_hal, df_ror], ignore_index = True) +date = datetime.datetime.now().strftime("%Y-%m-%d") ## format date has 2023-12-29 +df.to_csv(f"UGA-ror-childs--{date}.csv", index = False) + + +print("nb of RORs finded", 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def req_zenodo(uga_perimeter, record_type) : # verifier si la requete a bien fonctionnée if not res["continue"] : - print(r"/!\ oups, problem with the query") + print(r"\t/!\ oups, problem with the query") print(res["content"].status_code ) ## contient la réponse de la requête break @@ -128,9 +129,7 @@ for record_type in types_to_req : [all_dois.add(doi) for doi in temp_dois] -print("Zenodo nb of DOIs catched", - len(all_dois) - ) +print("\n\tnb DOIs finded\t", len(all_dois) ) ## ____z____ exporter la liste de DOI au format txt diff --git a/1-enrich-with-datacite/concatenet-enrich-dois.py b/1-enrich-with-datacite/concatenate-enrich-dois.py similarity index 67% rename from 1-enrich-with-datacite/concatenet-enrich-dois.py rename to 1-enrich-with-datacite/concatenate-enrich-dois.py index eb50b8f..78810fb 100644 --- a/1-enrich-with-datacite/concatenet-enrich-dois.py +++ b/1-enrich-with-datacite/concatenate-enrich-dois.py @@ -2,25 +2,25 @@ import z_personal_functions as my_functions import requests, json, random, pandas as pd +print("\n\nRunning concatenate-enrich-dois.py") + # ______0______ load DOIs and remove duplicate ## specifier la liste des entrepôts à importer -repo_list = ["nakala", "bso-via-hal", "datacite", "zenodo", "rdg"] +files_to_load = [ "zenodo", "datacite", "rdg", "bso-via-hal", "nakala" ] -dois_raw = my_functions.from_repos_load_dois(repo_list) -print("DOIs loaded\t\t\t", len(dois_raw)) +dois_raw = my_functions.from_files_load_dois(files_to_load) +print("\n\tDOIs loaded\t\t\t", len(dois_raw)) -## remove duplicate -dois = list(set(dois_raw)) -print("DOIs to treat\t\t\t", len(dois)) +dois = list(set(dois_raw)) ## remove duplicate +print("\tDOIs to treat\t\t", len(dois)) -# ______1_____ load metadata from dataCite and get specified metadatas +# ______1_____ load DOIs already treater & get md from DataCite for new one ## pour essayer avec un seul DOI -# # random doi 10.25656/01:8509 # temp_doi = dois[random.randint(0, len(dois))] -# #temp_doi = "10.57745/QYIAWX" +# #temp_doi = "10.57745/QYIAWX" - 10.25656/01:8509 # print(temp_doi) # raw_metadatas = my_functions.get_md_from_datacite(temp_doi) @@ -28,7 +28,7 @@ doi_error = [] # retrieve doi error temp_rows = [] # put data in dict before df df_old = pd.read_csv("../dois-uga.csv") -print(f"\nnb of dois already treated\t{len(df_old)}") +print(f"\n\tnb of DOIs already treated\t{len(df_old)}") # req dataCite and paste data following instructions for doi in dois : #[:300] @@ -38,8 +38,7 @@ for doi in dois : #[:300] #print(f"\talready treated\t\t{doi}") continue - ## get md from datacite - + ## ___n___ get md from datacite raw_md = my_functions.get_md_from_datacite(doi) ## to debug print(f"\t{doi}") @@ -48,7 +47,7 @@ for doi in dois : #[:300] doi_error.append(doi) continue - ## from manual instruction retrieve accurate data + ## ___n___ from manual instructions retrieve appropriate data selected_md = my_functions.parse_datacite_md(raw_md) ## placer les resultats dans un dictionnaire temp_rows.append(selected_md) ## ajouter ce dictionnaire à une liste print(f"\tadded\t\t{doi}") diff --git a/1-enrich-with-datacite/z_personal_functions.py b/1-enrich-with-datacite/z_personal_functions.py index d0159a5..fdd05d1 100644 --- a/1-enrich-with-datacite/z_personal_functions.py +++ b/1-enrich-with-datacite/z_personal_functions.py @@ -158,36 +158,26 @@ def parse_datacite_md(raw_datacite_mds): return doi_md -def from_repos_load_dois(repo_list) : - """ - from repo name (eg Zenodo) load file - """ - dois_raw = [] - - ## load all dois - for repo_name in repo_list : - dois_raw += load_dois_from_file(repo_name) - - return dois_raw - - -def load_dois_from_file(repo_name) : +def from_files_load_dois(files_name) : """ - charge les dois des fichiers texts - file name syntax "entrepot-dois.txt" - """ - - file_name = repo_name + "-dois.txt" - folder_path = "../0-collect-data/" - dois_in_repo = [] - - with open(folder_path + file_name) as f: - ## attention à la fin des lignes il y a un retour à la ligne, d'où le (line)-1 - ## on passer les DOI en miniscule également - [dois_in_repo.append( line[ :len(line)-1].lower()) for line in f.readlines()] - - print(f"{repo_name} DOIs \t\t {len(dois_in_repo)}") + load txt files which contains DOIs + """ + all_dois = [] - return dois_in_repo + for file_shortname in files_name : + file_fullname = file_shortname + "-dois.txt" + folder_path = "../0-collect-data/" + temp_loaded_dois = [] + + with open(folder_path + file_fullname) as f: + ## attention à la fin des lignes il y a un retour à la ligne, d'où le (line)-1 + ## lower DOI string also + [temp_loaded_dois.append( line[ :len(line)-1].lower()) for line in f.readlines()] + + print(f"\t{file_shortname:<10s}\t\t{len(temp_loaded_dois)}") + [all_dois.append(elem) for elem in temp_loaded_dois] + + + return all_dois diff --git a/2-produce-graph/hist--datasets-by-year.png b/2-produce-graph/hist--datasets-by-year.png index 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a/2-produce-graph/hist-quantity-by-year.py b/2-produce-graph/hist-quantity-by-year.py index 0469510..aa73c7a 100644 --- a/2-produce-graph/hist-quantity-by-year.py +++ b/2-produce-graph/hist-quantity-by-year.py @@ -4,11 +4,9 @@ import z_my_functions as my_fct df = my_fct.load_and_treat_csv() -print(df.columns) +#print(df.columns) -print("nb de datasets\t", len(df)) - ## publicationYear contient une année de 1995 : on reconstruit un champs année à partir de "created" : date d'enregistrement du dépot df["year"] = df["created"].str[:4] #print( df["year"].value_counts() ) @@ -20,21 +18,22 @@ df_hist.columns = ["year", "nb_dois"] #print("\n", df_hist) -## ____N____ do graph +## ____n____ do graph fig, (ax) = plt.subplots(figsize=(8, 6), dpi=100, facecolor='w', edgecolor='k') ax.bar(df_hist.year, df_hist.nb_dois , align='center', alpha = 1.0, color='#7e96c4', ecolor='black', label="tba") plt.xticks(df_hist.year.values) -## remove axi +## remove axis ax.spines['top'].set_visible(False) ax.spines['right'].set_visible(False) +ax.yaxis.grid(ls='--', alpha=0.4) ax.set_ylabel("number of datasets", labelpad = 10) plt.title(f"Number of datasets with a DataCite DOI by year", fontsize = 18, x = 0.5, y = 1.05, alpha = 0.6) plt.suptitle(f"n = {len(df)}", fontsize = 12, x = 0.5, y = 0.9, alpha = 0.6) plt.savefig("hist--datasets-by-year.png") - +print(f"\ngraph produced hist--datasets-by-year.png") diff --git a/2-produce-graph/pie--datacite-client.png b/2-produce-graph/pie--datacite-client.png index 1265c5ef5d24b5ec3361f09f56e611fffb3a18d3..4b39e4a150509105447059bc695154a9015cbaf9 100644 GIT binary patch literal 41386 zcmc$Gbx>CA*Dj(Wf+$KUDIzI?v~)-aNOyOGbf*G>q)JIQNOzZjfOJSB0s@lKoo8)- z-<<j8JO7?DXXbrJ*z9NTJ62rRwbuQ-mz5U7!XU&zK|#S1e<>`Ff`aOUf^uaR9SyFq z4gOq!e>fdPR2>wojUAlz?2J&P^c-v~tsN}Q^dCAI+1Z;}zh+^0&cICn(A2@f#-59j z(dvKSz+i1>!uas?;u}2Vrp-$=dlZyAddUA*zVK(8p`fG^hzkoUx+JVmJG&?vO@5u5 ziTxBSzDa)VC5`wOa>eT+X84Nvy3=@aV{f(Yj=nW|nx|UgK|lUANJ1_{f*|8CY2coO 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z+5FR2Fgn(JWMcykc%`jcx9%8lyx`*6Xmel!-BM}+9KpW!Z*3tfFa$b0jv9dSyi$-M zxY^ec!UJ-pl9K3QPypSNn6Iu<wL9v!`7sbT?)K*WMZkH0tH&k^?7a_e9RgQSuDvwR zZS@vl*4Od`maA=TZI|wEyL$O@vjRu1jOfMROMwHbOP4Oa02FC+d%YwNWY3G<8M9_F zHB4a<3VaP5Tx;IBvvT!c_HO+qHKj#iz+tX-U<-U3U-OH-!08QE)2-Kb7x%-uGR_LX nct><?i0QtdmpKG=KdWb~n-RC&?p6Oj1|aZs^>bP0l+XkKF0H5? diff --git a/2-produce-graph/pie-data-type.py b/2-produce-graph/pie-data-type.py index 4c89339..efb8a4a 100644 --- a/2-produce-graph/pie-data-type.py +++ b/2-produce-graph/pie-data-type.py @@ -4,7 +4,7 @@ import seaborn as sns import random df = my_fct.load_and_treat_csv() -print(df.columns) +#print(df.columns) df_type = df["resourceTypeGeneral"].value_counts() # print(df_type_raw) @@ -29,6 +29,7 @@ plt.legend(df_type.index, loc = (0.7, -0.1) ) plt.title(f"Type of datasets", fontsize = 20, x = 0.5, y = 1.03, alpha = 0.6) plt.suptitle(f"n = {len(df)}", fontsize = 11, x = 0.5, y = 0.9, alpha = 0.6) plt.savefig("pie--datacite-type.png") +print(f"\ngraph produced pie--datacite-type.png") # print(len(df)) \ No newline at end of file diff --git a/2-produce-graph/pie-datacite-client.py b/2-produce-graph/pie-datacite-client.py index d88394d..d7e7d3c 100644 --- a/2-produce-graph/pie-datacite-client.py +++ b/2-produce-graph/pie-datacite-client.py @@ -4,7 +4,7 @@ import seaborn as sns df = my_fct.load_and_treat_csv() -print(df.columns) +#print(df.columns) df_client_raw = df["client"].value_counts() @@ -34,6 +34,7 @@ plt.pie(df_client, labels = clients_name, colors = colors, autopct='%.0f%%') plt.title(f"Distribution of datasets by DataCite client", fontsize = 20, x = 0.5, y = 1.03, alpha = 0.6) plt.suptitle(f"n = {len(df)}", fontsize = 11, x = 0.5, y = 0.90, alpha = 0.6) plt.savefig("pie--datacite-client.png") +print(f"\ngraph produced pie--datacite-client.png") # print(len(df)) \ No newline at end of file diff --git a/README.md b/README.md index 29ecb7a..e22a585 100644 --- a/README.md +++ b/README.md @@ -20,7 +20,7 @@ _in process_ |-----------|---------------|---------------| |RDG |42 |contact, auteurs, producteur et contributeurs avec "UGA" OR "Grenoble" | |DataCite |730| creator et contributor avec ROR + clients | -|Zenodo |1035|creator et contributor avec "grenoble" | +|Zenodo |1041|creator et contributor avec "grenoble" | |Nakala |32 |UGA user identifiers | |BSO via HAL|32 |NA | |... | | diff --git a/dois-uga.csv b/dois-uga.csv index 655c2f0..36943a3 100644 --- a/dois-uga.csv +++ b/dois-uga.csv @@ -4036,3 +4036,470 @@ Note : les fichiers d'extension ipynb peuvent être lus en ligne à l'aide de l' 10.5281/zenodo.10205580,Proceedings of the 7th International Conference English Pronunciation: Issues and Practices (EPIP 7).[on line],Université Grenoble-Alpes,2023,en,ConferenceProceeding,Creative Commons Attribution 4.0 International,"This is the online, compiled proceedings from the 7th International Conference English Pronunciation: Issues and Practices (EPIP 7) which was held May 18–20, 2022 at Université Grenoble-Alpes, France. It includes 23 double-blind, peer-reviewed chapters written by authors from several countries, an introduction and a thematic index, and is licensed under the Creative Commons Attribution 4.0 International License. (To view a copy of the license, please go to: http://creativecommons.org/licenses/by/4.0/.)",api,True,findable,0,0,0,0,0,2023-11-25T08:33:50.000Z,2023-11-25T08:33:50.000Z,cern.zenodo,cern,"English pronunciation,second language pronunciation,language learning,language teaching,second language acquisition,phonetics,phonology,English pronunciation research","[{'subject': 'English pronunciation'}, {'subject': 'second language pronunciation'}, {'subject': 'language learning'}, {'subject': 'language teaching'}, {'subject': 'second language acquisition'}, {'subject': 'phonetics'}, {'subject': 'phonology'}, {'subject': 'English pronunciation research'}]",, 10.34746/cahierscostech48,Université Virtuelle Africaine (UVA) et universités partenaires en Afrique : Entretien commenté,Cahiers Costech,2018,fr,JournalArticle,Creative Commons Attribution Non Commercial Share Alike 4.0 International,"Cette publication qui n’a pas pour ambition de lancer un nouveau type d’entretien, se présente sous une forme originale structurée en deux parties. La première donne à voir la version initiale d’une proposition de publication dont l’objectif était de rendre compte d’un travail de terrain constitué par la transcription d’un entretien et de son analyse au regard du sujet de thèse. La seconde partie présente les améliorations apportées à la version initiale suite aux commentaires formulés par les deux enseignants-chercheurs responsables de la rubrique « Education et numérique » des Cahiers Costech sollicités pour la publication. L’intérêt de cette démarche est de mettre en évidence le travail de conscientisation du doctorant résultant des directives pédagogiques des relecteurs. ",fabricaForm,True,findable,0,0,0,0,0,2022-07-06T12:43:45.000Z,2022-07-06T12:43:46.000Z,inist.utc,vcob,Education et technologie - Méthodologie de recherche - Simondon,[{'subject': 'Education et technologie - Méthodologie de recherche - Simondon'}],, +10.6084/m9.figshare.22625635,"Additional file 10 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 10.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:10.000Z,2023-04-13T18:56:10.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['184741 Bytes'], +10.5061/dryad.6s5pn,Data from: Investigating the genetics of Bti resistance using mRNA tag sequencing: application on laboratory strains and natural populations of the dengue vector Aedes aegypti,Dryad,2013,en,Dataset,Creative Commons Zero v1.0 Universal,"Mosquito control is often the main method used to reduce mosquito-transmitted diseases. In order to investigate the genetic basis of resistance to the bio-insecticide Bacillus thuringiensis subsp. israelensis (Bti), we used information on polymorphism obtained from cDNA tag sequences from pooled larvae of laboratory Bti-resistant and susceptible Aedes aegypti mosquito strains to identify and analyse 1520 single nucleotide polymorphisms (SNPs). Of the 372 SNPs tested, 99.2% were validated using DNA Illumina GoldenGate® array, with a strong correlation between the allelic frequencies inferred from the pooled and individual data (r = 0.85). A total of 11 genomic regions and five candidate genes were detected using a genome scan approach. One of these candidate genes showed significant departures from neutrality in the resistant strain at sequence level. Six natural populations from Martinique Island were sequenced for the 372 tested SNPs with a high transferability (87%), and association mapping analyses detected 14 loci associated with Bti resistance, including one located in a putative receptor for Cry11 toxins. Three of these loci were also significantly differentiated between the laboratory strains, suggesting that most of the genes associated with resistance might differ between the two environments. It also suggests that common selected regions might harbour key genes for Bti resistance.",mds,True,findable,288,41,1,1,0,2013-06-05T16:30:58.000Z,2013-06-05T16:30:59.000Z,dryad.dryad,dryad,"Genomics/Proteomics,Ecotoxicology,Aedes aegypti","[{'subject': 'Genomics/Proteomics'}, {'subject': 'Ecotoxicology', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}, {'subject': 'Aedes aegypti', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}]",['137673 bytes'], +10.6084/m9.figshare.21285665.v1,Additional file 3 of Prognosis of lasso-like penalized Cox models with tumor profiling improves prediction over clinical data alone and benefits from bi-dimensional pre-screening,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 3. A document containing supplementary Figures 1-23 including the corresponding legends.,mds,True,findable,0,0,0,0,0,2022-10-06T07:36:18.000Z,2022-10-06T07:36:18.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Pharmacology,Immunology,FOS: Clinical medicine,69999 Biological Sciences not elsewhere classified,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Cancer","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",['3843262 Bytes'], +10.6084/m9.figshare.22620037,"Additional file 3 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 3: Candidate homozygous variants identified in the 6 consanguineous probands.,mds,True,findable,0,0,0,0,0,2023-04-13T14:39:41.000Z,2023-04-13T14:44:35.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['28253 Bytes'], +10.6084/m9.figshare.23994601.v1,Additional file 1 of Determination of different social groups’ level of knowledge about malaria in a multicultural Amazonian cross-border context,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Appendix 1. Factor analyses of multiple-choice variables assessing knowledge of symptoms.,mds,True,findable,0,0,0,0,0,2023-08-20T03:11:01.000Z,2023-08-20T03:11:02.000Z,figshare.ars,otjm,"Biological Sciences not elsewhere classified,Science Policy","[{'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Science Policy'}]",['19713 Bytes'], +10.25384/sage.c.6772590.v1,Beyond atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma: overall efficacy and safety of tyrosine kinase inhibitors in a real-world setting,SAGE Journals,2023,,Collection,Creative Commons Attribution 4.0 International,"Background:In patients with advanced hepatocellular carcinoma (HCC) progressing after atezolizumab and bevacizumab, the optimal therapeutic sequence is still unclear and no second-line agent has proven its efficacy.Objectives:The aim of this retrospective multicenter real-world cohort study was to provide an evaluation of the efficacy and safety of the use of second-line tyrosine kinase inhibitors (TKIs) in this population.Methods:All patients with advanced HCC, treated in first-line setting by atezolizumab–bevacizumab, and who received at least one dose of treatment with TKI were included in this study. All the data were retrospectively collected from medical records. The primary outcome was progression-free survival (PFS). Secondary outcomes were overall survival (OS), overall global survival (OGS), and safety. A total of 82 patients were included in this study.Results:Patients were assigned to the regorafenib group (<i>n</i> = 29, 35.4%) or other TKI (sorafenib <i>n</i> = 41, lenvatinib <i>n</i> = 8, or cabozantinib <i>n</i> = 4) group (<i>n</i> = 53). PFS was not significantly different between the two groups [2.6 <i>versus</i> 2.8 months, HR 1.07 (95% CI: 0.61–1.86), <i>p</i> = 0.818]. Median PFS rates were 2.6, 4.4, and 2.8 months in sorafenib-, lenvatinib-, and cabozantinib group, respectively. OS was statistically different between the regorafenib group and other TKI group [15.8 <i>versus</i> 7.0 months, HR 0.40 (95% CI: 0.20–0.79), <i>p</i> = 0.023]. When adjusting on confounding factors, there was still a difference in OS favoring the regorafenib group (adjusted hazard ratio 0.35, <i>p</i> = 0.019). OGS of patients who received regorafenib was improved compared to other TKI [18.6 <i>versus</i> 15.0 months, HR 0.42 (95% CI: 0.22–0.84), <i>p</i> = 0.036]. Twenty percent of patients had grade 3 and none had grade 4 or 5 adverse events. In patients who experienced disease progression and fit for a third-line treatment, 80% and 50% received cabozantinib in regorafenib group and other TKI group, respectively.Conclusion:Efficacy of any TKI in the second-line setting was not affected by atezolizumab–bevacizumab treatment as first-line therapy. The safety profile in the second-line setting was consistent with the results shown in pivotal studies. PFS rates of patients were similar, regardless of TKI type. Regorafenib was associated with better OS and OGS rates compared to other TKI. These data need to be confirmed in prospective comparative studies.",mds,True,findable,0,0,0,0,0,2023-08-03T00:08:51.000Z,2023-08-03T00:08:52.000Z,figshare.sage,sage,"Oncology and Carcinogenesis not elsewhere classified,Aged Health Care,Pharmacology and Pharmaceutical Sciences not elsewhere classified,Respiratory Diseases","[{'subject': 'Oncology and Carcinogenesis not elsewhere classified'}, {'subject': 'Aged Health Care'}, {'subject': 'Pharmacology and Pharmaceutical Sciences not elsewhere classified'}, {'subject': 'Respiratory Diseases'}]",, +10.5061/dryad.hqbzkh1jx,Chameleon biogeographic dispersal associated with extreme life history strategies,Dryad,2022,en,Dataset,Creative Commons Zero v1.0 Universal,"This dataset contains data and code that support the results in Weil, S.-S., Gallien, L., Lavergne, S., Börger, L., Hassler, G., Nicolaï, Michaël P. J., Allen, William L. (2022) Chameleon biogeographic dispersal associated with extreme life history strategies (DOI: 10.1111/ecog.06323). We used species distribution, phylogenetic and life history trait data of 181 chameleons to determine the relationship between three traits (coastal distribution, body size, position on the fast/slow life history continuum) and past dispersal probability on an evolutionary timescale using trait-dependent biogeographic models. We found that all three traits were associated with past biogeographical movements. Lineages having coastal distributions and those with large bodies had higher dispersal probabilities. Interestingly, chameleons with either very fast or very slow life history were more successful dispersers than species with an intermediate strategy. Together, the three traits “coastal, large-bodied and extreme life history†form a dispersal syndrome.",mds,True,findable,135,10,0,1,0,2022-07-25T23:28:52.000Z,2022-07-25T23:28:53.000Z,dryad.dryad,dryad,"FOS: Biological sciences,FOS: Biological sciences,Biogeography,Chamaeleonidae,dispersal,fast-slow life history continuum,species' traits,trait-dependent biogeography,BioGeoBEARS","[{'subject': 'FOS: Biological sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Biogeography', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}, {'subject': 'Chamaeleonidae'}, {'subject': 'dispersal'}, {'subject': 'fast-slow life history continuum'}, {'subject': ""species' traits""}, {'subject': 'trait-dependent biogeography'}, {'subject': 'BioGeoBEARS'}]",['54898295 bytes'], +10.5061/dryad.c2fqz616h,Biotic homogenisation in bird communities leads to large-scale changes in species associations,Dryad,2020,en,Dataset,Creative Commons Zero v1.0 Universal,"This is the dataset used for the manuscript Biotic homogenisation in bird communities leads to large-scale changes in species associations Aim: The impact of global change on biodiversity is commonly assessed in terms of changes in species distributions, community richness and community composition. Whether and how much associations between species, i.e. the degree of correlation in their spatial co-occurrence, are also changing is much less documented and mostly limited to local studies of ecological networks. In this study, we quantify changes in large-scale patterns of species associations in bird communities in relation to changes in species composition. Location: France. Time period: 2001-2017. Major taxa studied: Common breeding birds. Methods: We use network approaches to build three community-aggregated indices reflecting complementary aspects of species association networks. We characterise the spatio-temporal dynamics of these indices using a large-scale and high-resolution dataset of bird co-abundances of 109 species monitored for 17 years (2001-2017) from 1,969 sites across France. We finally test whether spatial and temporal changes in species association networks are related to species homogenisation estimated as the spatio-temporal dynamics of β-diversity and the proportion of habitat generalists. The consistency of these relationships is tested across three main habitats, namely woodland, grassland and human settlements. Results: We document a directional change in association-based indices in response to modifications in β-diversity and in the proportion of generalists in space and time. Weaker associations and sparser networks were related to lower β-diversity and a higher proportion of generalists, suggesting an overlooked aspect of biotic homogenisation affecting species associations. We report that this overall pattern is not constant across habitats, with opposite relationships between biotic homogenisation and change in species association networks in urban versus forest communities suggesting distinct homogenisation processes. Main Conclusions: Although species association contain only partial signatures of species interactions, our study highlights that biotic homogenisation translates to finer changes in community structure by affecting the number, strength and type of species associations.",mds,True,findable,176,21,0,0,0,2021-01-05T18:39:07.000Z,2021-01-05T18:39:08.000Z,dryad.dryad,dryad,,,['226536182 bytes'], +10.6084/m9.figshare.22807641,Additional file 2 of Phenotype and imaging features associated with APP duplications,figshare,2023,,Image,Creative Commons Attribution 4.0 International,Additional file 2: Supp Figure 2. MRI scans of three patients from the BES_262 family showing the large heterogeneity of cerebral imaging. A: MRI of 262-001; B: MRI of 262-003; C: MRI of 262-004.,mds,True,findable,0,0,0,0,0,2023-05-12T03:40:50.000Z,2023-05-12T03:40:51.000Z,figshare.ars,otjm,"Biochemistry,Medicine,Cell Biology,Neuroscience,Science Policy","[{'subject': 'Biochemistry'}, {'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Neuroscience'}, {'subject': 'Science Policy'}]",['779176 Bytes'], +10.5061/dryad.mkkwh70x8,"Influence of climate, soil and land cover on plant species distribution in the European Alps",Dryad,2020,en,Dataset,Creative Commons Zero v1.0 Universal,"Although the importance of edaphic factors and habitat structure for plant growth and survival is known, both are often neglected in favor of climatic drivers when investigating the spatial patterns of plant species and diversity. Yet, especially in mountain ecosystems with complex topography, missing edaphic and habitat components may be detrimental for a sound understanding of biodiversity distribution. Here, we compare the relative importance of climate, soil and land cover variables when predicting the distributions of 2’616 vascular plant species in the European Alps, representing approximately two thirds of all European Flora. Using presence-only data, we built point-process models (PPMs) to relate species observations to different combinations of covariates. We evaluated the PPMs through block cross-validations, and assessed the independent contributions of climate, soil and land cover covariates to predict plant species distributions using an innovative predictive partitioning approach. We found climate to be the most influential driver of spatial patterns in plant species with a relative influence of ~58.5% across all species, with decreasing importance from low to high elevations. Soil (~20.1%) and land cover (~21.4%), overall, were less influential than climate, but increased in importance along the elevation gradient. Furthermore, land cover showed strong local effects in lowlands, while the contribution of soil stabilized at mid-elevations. The decreasing influence of climate with elevation is explained by increasing endemism, and the fact that climate becomes more homogeneous as habitat diversity declines at higher altitudes. In contrast, soil predictors were found to follow the opposite trend. Additionally, at low elevations, human-mediated land cover effects appear to reduce the importance of climate predictors. We conclude that soil and land cover are, like climate, principal drivers of plant species distribution in the European Alps. While disentangling their effects remains a challenge, future studies can benefit markedly by including soil and land cover effects when predicting species distributions.",mds,True,findable,276,53,0,1,0,2020-08-17T23:39:17.000Z,2020-08-17T23:39:19.000Z,dryad.dryad,dryad,"plant species,European Alps,environmental predictors,Soil Influence,Climate Influence,Land cover Influence,Elevation Preferences,Soil Preferences,Vegetation Types,Model Responses,Influence Outputs,Flora Alpina,species names,Species codes,Plots,Pipelines,Predictive Partitioning Analysis","[{'subject': 'plant species'}, {'subject': 'European Alps'}, {'subject': 'environmental predictors'}, {'subject': 'Soil Influence'}, {'subject': 'Climate Influence'}, {'subject': 'Land cover Influence'}, {'subject': 'Elevation Preferences'}, {'subject': 'Soil Preferences'}, {'subject': 'Vegetation Types'}, {'subject': 'Model Responses'}, {'subject': 'Influence Outputs'}, {'subject': 'Flora Alpina'}, {'subject': 'species names'}, {'subject': 'Species codes'}, {'subject': 'Plots'}, {'subject': 'Pipelines'}, {'subject': 'Predictive Partitioning Analysis'}]",['3008712374 bytes'], +10.6084/m9.figshare.c.6272697,Synchronization of small-scale seismic clusters reveals large-scale plate deformation,figshare,2022,,Collection,Creative Commons Attribution 4.0 International,"Abstract It has long been observed that periods of intense seismic activity in a region alternate with periods of relative quiescence, but establishing whether or not this intermittency is driven by broad-scale physical processes occurring in the Earth, remains a challenge. Here, we address this question of long-range triggering by a large-scale analysis of evolution of the seismicity between 2003 and 2017 in the Anatolia region. Two multi-year periods of synchronous high seismicity rate in 27 seismicity clusters across the Anatolian plate are evidenced before a relatively uniform quiescence period. We argue that two remote tectonic processes are important for the timing of these activities: the 2004 M9.2 Sumatra earthquake and the 2008–2011 episode of slab rollback/deformation in the Hellenic subduction, even if a clear causal mechanism is still lacking. Graphical Abstract",mds,True,findable,0,0,0,0,0,2022-10-30T04:22:22.000Z,2022-10-30T04:22:22.000Z,figshare.ars,otjm,"Geology,FOS: Earth and related environmental sciences","[{'subject': 'Geology'}, {'subject': 'FOS: Earth and related environmental sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.c.6821914.v1,Survey of adolescents’ needs and parents’ views on sexual health in juvenile idiopathic arthritis,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Although the advent of new therapeutics for juvenile idiopathic arthritis (JIA) patients has considerably lessened the impact of the disease and reduced its sequelae, the outcomes of JIA remain important in their lives. Disease repercussions and side effects of treatments may affect sexual health and cause psychological distress. This aim of the study was to determine the expectations of adolescent JIA patients and the perceptions of their parents regarding knowledge and communication with healthcare providers (HCPs) in the field of sexual health (SH). Methods In France, from September 2021 to April 2022, a survey was conducted, using anonymous self-administered questionnaires, among JIA patients (adults (aged 18–45 years) to provide insights from their recollection of their adolescence) and their parents in nine rheumatology centers and three patient associations. Results The responses to the 76 patient questionnaires and 43 parent questionnaires that were collected were analyzed. Half of the patients thought JIA impacted their romantic relationships, but the results were less clear-cut for their sexual activity; and 58.7% of the patients said they would be comfortable discussing the subject with HCPs, but only 26.3% had done so, mainly regarding biomedical issues. The patients and their parents thought that ideally, the topic should be addressed in an individual patient education session at the hospital (51.3% and 34.9%, respectively), in a regular consultation (47.4% and 53.5%), or in a dedicated consultation requested by the adolescent without the adolescent’s parents being informed (38.2% and 20.9%). Most of the respondents thought HCPs should be proactive in SH (77.6% of the patients and 69.8% of their parents). More patients than parents said the following digital information tools must be used: videos (29.0% vs. 9.3%, p = 0.0127) and smartphone applications (25.0% vs. 9.3%, p = 0.0372). Conclusion HCPs should consider addressing the unmet need for SH discussions during their patient encounters. To meet this need, we propose concrete actions in line with the wishes of patients and parents. Clinical trial registration number NCT04791189.",mds,True,findable,0,0,0,0,0,2023-09-06T17:23:01.000Z,2023-09-06T17:23:02.000Z,figshare.ars,otjm,"Medicine,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}]",, +10.5281/zenodo.10419096,"Sliding velocity, water discharge, water pressure, and rainfall time series at Argentière Glacier between 2019 and 2021",Zenodo,2023,,Dataset,Creative Commons Attribution 4.0 International,"Files Description: + +==================================cavitometer_2019-2021.dat:================================== + +Contains 30-min sampled values of recorded sliding velocities at the cavitometer. + +Column 1 = DateColumn 2 = Velocity (mm/hour) + +================================water_discharge_2019-2021.dat:================================ + +Contains 15-min sampled values of recorded water discharge at the glacier outlet. + +Column 1 = DateColumn 2 = Water discharge (m3/s) + +================================water_pressure_2019-2021.dat:================================ + +Contains 30-min sampled values of recorded water pressure at the borehole BH2. + +Column 1 = DateColumn 2 = Water pressure (bar) + +================================rainfall_2019-2021.dat:================================ + +Contains 30-min sampled values of recorded rainfall at the meteo station. + +Column 1 = DateColumn 2 = Rainfall (mm w.eq./hour)",api,True,findable,0,0,0,0,0,2023-12-22T13:03:53.000Z,2023-12-22T13:03:54.000Z,cern.zenodo,cern,,,, +10.48440/gfz.4.8.2021.002, The H2020 REFLECT project: Deliverable 4.1 - User’s Guide of a Coupled Hydro-Thermal-Chemical Code for Fluids,GFZ German Research Centre for Geosciences,2021,en,Text,Creative Commons Attribution 4.0 International,"This document presents the developed code, porousMedia4Foam, an open-source hydrogeochemical package that can decipher fluid flow and chemical reactive processes occurring within multi- {scale, dimensional, phase, compositional} environments. This report gives details regarding the installation of porousMedia4Foam, running the first simulations and describing many application cases in single-phase and multiphase systems. ",fabricaForm,True,findable,0,0,0,0,0,2021-07-14T12:49:11.000Z,2021-09-02T15:59:00.000Z,tib.gfzbib,gfz,,,['55 pages'],['pdf'] +10.6084/m9.figshare.20080019.v3,Views Evolution 5 Minutes Frequency,figshare,2022,,Dataset,Creative Commons Attribution 4.0 International,"This dataset contains 1012 videos posted between February 2, 2022 and February 16, 2022. For every video it records the amount of views every 5 minutes.",mds,True,findable,0,0,0,0,0,2022-07-18T11:03:55.000Z,2022-07-18T11:03:56.000Z,figshare.ars,otjm,,,['98488643 Bytes'], +10.5281/zenodo.10229533,Research compendium to reproduce analyses and figures of the article: Interspecific interactions influence bird population responses to global changes by Gaüzère et al. submitted in Ecology Letters,Zenodo,2023,,Software,Creative Commons Attribution 4.0 International,"Research compendium to reproduce analyses and figures of the article: +_Interspecific interactions influence bird population responses to global changes_ +by Gaüzère _et al._ submitted in _Ecology Letters_ + +#' Compendium authors +#' @author Pierre Gaüzère, \email{pierre.gauzere@@gmail.com}, + +## General + + This repository is structured as follow: + + - `data/`: contains data required to reproduce figures and tables + - `analyses/`: contains scripts organized sequentially. prepare data -> run model -> vizualize model outputs -> .. + - `outputs/`: follows the structure of analyses. Contains intermediate numeric + results used to produce the figures + - `figures_tables/`: Contains the figures of the paper + +## Figures & tables + + Figures will be stored in `figures_tables/`. + Tables will be stored in `outputs/`.",api,True,findable,0,0,0,0,0,2023-11-30T15:03:08.000Z,2023-11-30T15:03:08.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.22599661.v1,Additional file 1 of Procalcitonin to reduce exposure to antibiotics and individualise treatment in hospitalised old patients with pneumonia: a randomised study,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1.,mds,True,findable,0,0,0,0,0,2023-04-13T09:42:55.000Z,2023-04-13T09:42:55.000Z,figshare.ars,otjm,"Space Science,Medicine,Immunology,FOS: Clinical medicine,Cancer,111714 Mental Health,FOS: Health sciences,110309 Infectious Diseases","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '110309 Infectious Diseases', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}]",['317731 Bytes'], +10.6084/m9.figshare.24188536,Transformative learning in clinical reasoning: a meta-synthesis in undergraduate primary care medical education,Taylor & Francis,2023,,Text,Creative Commons Attribution 4.0 International,"Clinical reasoning is a vital medical education skill, yet its nuances in undergraduate primary care settings remain debated. This systematic review explores clinical reasoning teaching and learning intricacies within primary care. We redefine clinical reasoning as dynamically assimilating and prioritising synthesised patient, significant other, or healthcare professional information for diagnoses or non-diagnoses. This focused meta-synthesis applies transformative learning theory to primary care clinical reasoning education. A comprehensive analysis of 29 selected studies encompassing various designs made insights into clinical reasoning learning dimensions visible. Primary care placements in varying duration and settings foster diverse instructional methods like bedside teaching, clinical consultations, simulated clinics, virtual case libraries, and more. This review highlights the interplay between disease-oriented and patient-centred orientations in clinical reasoning learning. Transformative learning theory provides an innovative lens, revealing stages of initiation, persistence, time and space, and competence and confidence in students’ clinical reasoning evolution. Clinical teachers guide this transformation, adopting roles as fortifiers, connoisseurs, mediators, and monitors. Patient engagement spans passive to active involvement, co-constructing clinical reasoning. The review underscores theoretical underpinnings’ significance in shaping clinical reasoning pedagogy, advocating broader diversity. Intentional student guidance amid primary care complexities is vital. Utilising transformative learning, interventions bridging cognitive boundaries enhance meaningful clinical reasoning learning experiences. This study contributes insights for refining pedagogy, encouraging diverse research, and fostering holistic clinical reasoning development.",mds,True,findable,0,0,0,1,0,2023-09-24T15:20:05.000Z,2023-09-24T15:20:06.000Z,figshare.ars,otjm,"Medicine,Neuroscience,Biotechnology,Cancer,Mental Health,Hematology,Infectious Diseases,FOS: Health sciences","[{'subject': 'Medicine'}, {'subject': 'Neuroscience'}, {'subject': 'Biotechnology'}, {'subject': 'Cancer'}, {'subject': 'Mental Health'}, {'subject': 'Hematology'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['44790 Bytes'], +10.5061/dryad.t33v4k14,Data from: Blocking human contaminant DNA during PCR allows amplification of rare mammal species from sedimentary ancient DNA,Dryad,2011,en,Dataset,Creative Commons Zero v1.0 Universal,"Analyses of degraded DNA are typically hampered by contamination, especially when employing universal primers such as commonly used in environmental DNA studies. In addition to false-positive results, the amplification of contaminant DNA may cause false-negative results due to competition, or bias, during the PCR. In this study, we test the utility of human-specific blocking primers in mammal diversity analyses of ancient permafrost samples from Siberia. Using quantitative PCR (qPCR) on human and mammoth DNA we first optimised the design and concentration of blocking primer in the PCR. Subsequently, 454 pyrosequencing of ancient permafrost samples amplified with and without the addition of blocking primer revealed that DNA sequences from a diversity of mammalian representatives of the Beringian megafauna were retrieved only when the blocking primer was added to the PCR. Notably, we observe the first retrieval of woolly rhinoceros (C. antiquitatis) DNA from ancient permafrost cores. In contrast, reactions without blocking primer resulted in complete dominance by human DNA sequences. These results demonstrate that in ancient environmental analysis, the PCR can be biased towards amplification of contaminant sequences to such an extent that retrieval of the endogenous DNA is severely restricted. The application of blocking primers is a promising tool to avoid this bias and can greatly enhance the quantity and the diversity of the endogenous DNA sequences that are amplified.",mds,True,findable,269,13,1,2,0,2011-09-09T15:51:56.000Z,2011-09-09T15:51:56.000Z,dryad.dryad,dryad,"Genomics/Proteomics,Mammalia,Bioinfomatics/Phyloinfomatics","[{'subject': 'Genomics/Proteomics'}, {'subject': 'Mammalia'}, {'subject': 'Bioinfomatics/Phyloinfomatics'}]",['777804 bytes'], +10.6084/m9.figshare.21351214,Additional file 1 of Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Fig. S1. Study flowchart. Table S1. Baseline characteristics and mortality in the groups with vs. without mild-to-moderate postresuscitation shock (PRS) at intensive-care-unit (ICU) admission. Table S2. Multivariate logistic regression modelling to identify admission variables associated with a favourable outcome on day 90 in the overall population (n = 532).,mds,True,findable,0,0,0,0,0,2022-10-18T03:24:06.000Z,2022-10-18T03:24:07.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Physiology,FOS: Biological sciences,Pharmacology,Biotechnology,Cancer,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Physiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}]",['78458 Bytes'], +10.5061/dryad.v41ns1rwx,Data for: Environmental and anthropogenic constraints on animal space use drive extinction risk worldwide,Dryad,2021,en,Dataset,Creative Commons Zero v1.0 Universal,"Animals require a certain amount of habitat to persist and thrive, and habitat loss is one of the most critical drivers of global biodiversity decline. While habitat requirements have been predicted by relationships between species traits and home range size, little is known about constraints imposed by environmental conditions and human impacts on a global scale. Our meta-analysis of 395 vertebrate species shows that global climate gradients in temperature and precipitation exert indirect effects via primary productivity, generally reducing space requirements. Human pressure, however, reduces realized space use due to ensuing limitations in available habitat, particularly for large carnivores. We show that human pressure drives extinction risk by increasing the mismatch between space requirements and availability. We use large-scale climate gradients to predict current species extinction risk across global regions, which also offers an important tool for predicting future extinction risk due to ongoing space loss and climate change.",mds,True,findable,247,42,0,0,0,2021-08-06T22:45:24.000Z,2021-08-06T22:45:26.000Z,dryad.dryad,dryad,,,['204387 bytes'], +10.6084/m9.figshare.21285659,Additional file 1 of Prognosis of lasso-like penalized Cox models with tumor profiling improves prediction over clinical data alone and benefits from bi-dimensional pre-screening,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 1. A document containing supplementary materials.,mds,True,findable,0,0,0,0,0,2022-10-06T07:36:16.000Z,2022-10-06T07:36:16.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Pharmacology,Immunology,FOS: Clinical medicine,69999 Biological Sciences not elsewhere classified,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Cancer","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",['112261 Bytes'], +10.5281/zenodo.10000775,Metallic nickel pillar X-ray spectral ptychographic dataset,Zenodo,2023,,Dataset,Creative Commons Attribution 4.0 International,"This dataset was acquired at the SWING beamline at the French synchrotron SOLEIL. The dataset was obtained by conducting spectral 2D X-ray ptychography on a 7-micron diameter metallic nickel pillar. An energy scan was performed from 8.3 KeV to 8.4 KeV with a 1 eV step, including the resonant energy of nickel at 8.333 KeV. For each energy acquisition, the ptychographic scanning parameters consisted of 242 diffraction patterns from a field of view of 14x12 mm², with an exposure time of 100 ms per point. The ptychographic reconstruction was carried out using the PtychoShelves Matlab software package, involving 200 iterations of the difference map (DM) algorithm, followed by 100 iterations of the maximum likelihood (ML) algorithm.",api,True,findable,0,0,0,0,0,2023-10-13T14:05:22.000Z,2023-10-13T14:05:22.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.22625632,"Additional file 9 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 9.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:14.000Z,2023-04-13T18:56:15.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['1022601 Bytes'], +10.5061/dryad.tdz08kq05,Mismatches between birds' spatial and temporal dynamics reflect their delayed response to global changes,Dryad,2021,en,Dataset,Creative Commons Zero v1.0 Universal,"Global changes alter the dynamics of biodiversity, and are forecasted to continue or worsen in the decades to come. Modelling approaches used to anticipate these impacts are mainly based on the equivalence between spatial and temporal response to environmental forcings, generally called space-for-time substitution. However, several processes are known to generate deviations between spatial and temporal responses, potentially undermining the prediction based on space-for-time substitution. We here used high-resolution data from the french breeding bird survey to quantify and map the deviation between spatial and temporal patterns of bird abundances resulting from the dynamics of 124 species monitored in 2133 sites between 2001 and 2012. Using independent empirical data, we then tested specific predictions linked to the determinants (anthropogenic activities) and processes (lagged responses to environmental changes) potentially generating these deviations. We found that deviations between spatial and temporal patterns of abundances were particularly structured in space for bird communities. Following our predictions, these space–time deviations were positively correlated with the human influence on ecosystems, and linked with colonization–extinction ratios and community completeness, two markers of ongoing delayed responses to environmental changes. Our results suggest that the deviations between spatial and temporal patterns are related to recent anthropogenic environmental changes and disequilibrium responses to these changes. Investigating deviations between spatial and temporal patterns of biodiversity might open promising perspectives for a formal quantification of disequilibrium state of biodiversity at large spatial scale.",mds,True,findable,147,8,0,1,0,2021-10-29T19:44:51.000Z,2021-10-29T19:44:53.000Z,dryad.dryad,dryad,"FOS: Natural sciences,FOS: Natural sciences","[{'subject': 'FOS: Natural sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Natural sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['1083272 bytes'], +10.5281/zenodo.10214411,Radiofrequency to Microwave Coherent Manipulation of an Organometallic Electronic Spin Qubit Coupled to a Nuclear Qudit,Zenodo,2021,,Dataset,Creative Commons Attribution 4.0 International,"Dataset containing ASCII files for Figures 2-8 of the paper +Radiofrequency to Microwave Coherent Manipulation of an Organometallic Electronic Spin Qubit Coupled to a Nuclear Qudit +Inorg. Chem. 2021, 60, 11273−11286",api,True,findable,0,0,0,0,0,2023-11-29T12:01:19.000Z,2023-11-29T12:01:19.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.c.6804540,Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Pneumocystis jirovecii pneumonia (PJP) is an opportunistic, life-threatening disease commonly affecting immunocompromised patients. The distribution of predisposing diseases or conditions in critically ill patients admitted to intensive care unit (ICU) and subjected to diagnostic work-up for PJP has seldom been explored. Materials and methods The primary objective of the study was to describe the characteristics of ICU patients subjected to diagnostic workup for PJP. The secondary objectives were: (i) to assess demographic and clinical variables associated with PJP; (ii) to assess the performance of Pneumocystis PCR on respiratory specimens and serum BDG for the diagnosis of PJP; (iii) to describe 30-day and 90-day mortality in the study population. Results Overall, 600 patients were included in the study, of whom 115 had presumptive/proven PJP (19.2%). Only 8.8% of ICU patients subjected to diagnostic workup for PJP had HIV infection, whereas hematological malignancy, solid tumor, inflammatory diseases, and solid organ transplants were present in 23.2%, 16.2%, 15.5%, and 10.0% of tested patients, respectively. In multivariable analysis, AIDS (odds ratio [OR] 3.31; 95% confidence interval [CI] 1.13–9.64, p = 0.029), non-Hodgkin lymphoma (OR 3.71; 95% CI 1.23–11.18, p = 0.020), vasculitis (OR 5.95; 95% CI 1.07–33.22, p = 0.042), metastatic solid tumor (OR 4.31; 95% CI 1.76–10.53, p = 0.001), and bilateral ground glass on CT scan (OR 2.19; 95% CI 1.01–4.78, p = 0.048) were associated with PJP, whereas an inverse association was observed for increasing lymphocyte cell count (OR 0.64; 95% CI 0.42–1.00, p = 0.049). For the diagnosis of PJP, higher positive predictive value (PPV) was observed when both respiratory Pneumocystis PCR and serum BDG were positive compared to individual assay positivity (72% for the combination vs. 63% for PCR and 39% for BDG). Cumulative 30-day mortality and 90-day mortality in patients with presumptive/proven PJP were 52% and 67%, respectively. Conclusion PJP in critically ill patients admitted to ICU is nowadays most encountered in non-HIV patients. Serum BDG when used in combination with respiratory Pneumocystis PCR could help improve the certainty of PJP diagnosis.",mds,True,findable,0,0,0,0,0,2023-08-25T03:21:17.000Z,2023-08-25T03:21:17.000Z,figshare.ars,otjm,"Medicine,Biotechnology,Immunology,FOS: Clinical medicine,Biological Sciences not elsewhere classified,Cancer,Science Policy,Mental Health,Infectious Diseases,FOS: Health sciences,Virology","[{'subject': 'Medicine'}, {'subject': 'Biotechnology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}, {'subject': 'Mental Health'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Virology'}]",, +10.6084/m9.figshare.22625620.v1,"Additional file 5 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 5.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:09.000Z,2023-04-13T18:48:09.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['182300 Bytes'], +10.6084/m9.figshare.22027566,Students’ and tutors’ experiences of remote ‘student–patient’ consultations,Taylor & Francis,2023,,Text,Creative Commons Attribution 4.0 International,"Remote consulting has become part of the medical student clinical experience in primary care, but little research exists regarding the impact on learning. To describe the experiences of General Practitioner (GP) educators and medical students in using student-led remote consultations as an educational tool. A qualitative, explorative study conducted at four UK medical schools. GP educators and medical students were purposively sampled and interviewed. Nine themes arose: practical application, autonomy, heuristics, safety, triage of undifferentiated patients, clinical reasoning, patient inclusion in student education, student–patient interaction, and student–doctor interaction. Remote consulting has become part of the clinical placement experience. This has been found to expose students to a wider variety of clinical presentations. Verbal communication, history-taking, triage, and clinical reasoning skills were practised through remote consulting, but examination skills development was lacking. Students found building rapport more challenging, although this was mitigated by having more time with patients. Greater clinical risk was perceived in remote consulting, which had potential to negatively impact students’ psychological safety. Frequent debriefs could ameliorate this risk and positively impact student–doctor relationships. Student autonomy and independence increased due to greater participation and responsibility. Pre-selection of patients could be helpful but had potential to expose students to lower complexity patients. Practice pointsRemote consulting confers unique educational benefits.Remote consulting can help develop history-taking and communication skills, as well as clinical reasoning skills.The psychological safety of the student and the supervisory risk of the tutor can be impacted by remote consulting, but frequent debriefs between the student and tutor can help mitigate this risk.Learning how to conduct remote, and face-to-face consultations is important in medical education. Practice points Remote consulting confers unique educational benefits. Remote consulting can help develop history-taking and communication skills, as well as clinical reasoning skills. The psychological safety of the student and the supervisory risk of the tutor can be impacted by remote consulting, but frequent debriefs between the student and tutor can help mitigate this risk. Learning how to conduct remote, and face-to-face consultations is important in medical education.",mds,True,findable,0,0,0,1,0,2023-02-06T19:20:05.000Z,2023-02-06T19:20:05.000Z,figshare.ars,otjm,"Medicine,Neuroscience,Biotechnology,Science Policy,Mental Health,Hematology,Plant Biology,FOS: Biological sciences","[{'subject': 'Medicine'}, {'subject': 'Neuroscience'}, {'subject': 'Biotechnology'}, {'subject': 'Science Policy'}, {'subject': 'Mental Health'}, {'subject': 'Hematology'}, {'subject': 'Plant Biology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['17511 Bytes'], +10.6084/m9.figshare.24091567.v1,Additional file 2 of Survey of adolescents’ needs and parents’ views on sexual health in juvenile idiopathic arthritis,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary Material 2,mds,True,findable,0,0,0,0,0,2023-09-06T17:23:05.000Z,2023-09-06T17:23:05.000Z,figshare.ars,otjm,"Medicine,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}]",['286208 Bytes'], +10.5061/dryad.4kn05,Data from: Spatio-temporal monitoring of deep-sea communities using metabarcoding of sediment DNA and RNA,Dryad,2017,en,Dataset,Creative Commons Zero v1.0 Universal,"We assessed spatio-temporal patterns of diversity in deep-sea sediment communities using metabarcoding. We chose a recently developed eukaryotic marker based on the v7 region of the 18S rRNA gene. Our study was performed in a submarine canyon and its adjacent slope in the Northwestern Mediterranean Sea, sampled along a depth gradient at two different seasons. We found a total of 5,569 molecular operational taxonomic units (MOTUs), dominated by Metazoa, Alveolata and Rhizaria. Among metazoans, Nematoda, Arthropoda and Annelida were the most diverse. We found a marked heterogeneity at all scales, with important differences between layers of sediment and significant changes in community composition with zone (canyon vs slope), depth, and season. We compared the information obtained from metabarcoding DNA and RNA and found more total MOTUs and more MOTUs per sample with DNA (ca. 20% and 40% increase, respectively). Both datasets showed overall similar spatial trends, but most groups had higher MOTU richness with the DNA template, while others, such as nematodes, were more diverse in the RNA dataset. We provide metabarcoding protocols and guidelines for biomonitoring of these key communities in order to generate information applicable to management efforts.",mds,True,findable,320,40,1,2,0,2016-11-28T16:42:56.000Z,2016-11-28T16:42:57.000Z,dryad.dryad,dryad,"meiofauna,Eukarya,submarine canyons,biomonitoring,present day,18S,Holocene,sediments,eRNA","[{'subject': 'meiofauna'}, {'subject': 'Eukarya'}, {'subject': 'submarine canyons'}, {'subject': 'biomonitoring'}, {'subject': 'present day'}, {'subject': '18S'}, {'subject': 'Holocene'}, {'subject': 'sediments'}, {'subject': 'eRNA'}]",['71620036 bytes'], +10.6084/m9.figshare.22620043.v1,"Additional file 5 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 5: Quantitative PCR results comparing relative expression of NOS3 mRNA in cells transfected with the wild type and with the M035 mutated cDNA.,mds,True,findable,0,0,0,0,0,2023-04-13T14:40:01.000Z,2023-04-13T15:25:46.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['14233 Bytes'], +10.5281/zenodo.10048443,Spring snow albedo feedback in daily data over Russia: Comparing in-situ measurements with reanalysis products,Zenodo,2023,,Text,Creative Commons Attribution 4.0 International,"Poster for the ASSW 2017 and AGU 2016 conference showing results from Wegmann et al. 2018. + +Wegmann, M., Dutra, E., Jacobi, H.W. & Zolina, O. (2018). Spring snow albedo feedback over Northern Eurasia: Comparing in-situ measurements with reanalysis products. The Cryosphere, 12(6), 1887-1898",api,True,findable,0,0,0,0,0,2023-10-27T18:27:29.000Z,2023-10-27T18:27:29.000Z,cern.zenodo,cern,"snow,albedo,reanalysis,climate,observations,russia","[{'subject': 'snow'}, {'subject': 'albedo'}, {'subject': 'reanalysis'}, {'subject': 'climate'}, {'subject': 'observations'}, {'subject': 'russia'}]",, +10.6084/m9.figshare.c.6627379,"Multiple trauma in pregnant women: injury assessment, fetal radiation exposure and mortality. A multicentre observational study",figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Fetal radiation exposure in pregnant women with trauma is a concern. The purpose of this study was to evaluate fetal radiation exposure with regard to the type of injury assessment performed. Methods It is a multicentre observational study. The cohort study included all pregnant women suspected of severe traumatic injury in the participating centres of a national trauma research network. The primary outcome was the cumulative radiation dose (mGy) received by the fetus with respect to the type of injury assessment initiated by the physician in charge of the pregnant patient. Secondary outcomes were maternal and fetal morbi-mortality, the incidence of haemorrhagic shock and the physicians’ imaging assessment with consideration of their medical specialty. Results Fifty-four pregnant women were admitted for potential major trauma between September 2011 and December 2019 in the 21 participating centres. The median gestational age was 22 weeks [12–30]. 78% of women (n = 42) underwent WBCT. The remaining patients underwent radiographs, ultrasound or selective CT scans based on clinical examination. The median fetal radiation doses were 38 mGy [23–63] and 0 mGy [0–1]. Maternal mortality (6%) was lower than fetal mortality (17%). Two women (out of 3 maternal deaths) and 7 fetuses (out of 9 fetal deaths) died within the first 24 h following trauma. Conclusions Immediate WBCT for initial injury assessment in pregnant women with trauma was associated with a fetal radiation dose below the 100 mGy threshold. Among the selected population with either a stable status with a moderate and nonthreatening injury pattern or isolated penetrating trauma, a selective strategy seemed safe in experienced centres.",mds,True,findable,0,0,0,0,0,2023-05-03T03:19:17.000Z,2023-05-03T03:19:17.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Biotechnology,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Developmental Biology,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Biotechnology'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Developmental Biology'}, {'subject': 'Science Policy'}]",, +10.5061/dryad.zw3r2285q,"Data from: Last Glacial Maximum environmental conditions at Andøya, northern Norway; evidence for a northern ice-edge ecological “hotspotâ€",Dryad,2020,en,Dataset,Creative Commons Zero v1.0 Universal,"Andøya on the NW coast of Norway is a key site for understanding the Last Glacial Maximum (LGM) in northern Europe. Controversy has arisen concerning the local conditions, especially about the timing and extent of local glacial cover, maximum July temperatures and whether pine and/or spruce could have grown there. We reviewed all existing data and add newly analysed ancient sedimentary DNA, pollen, macrofossils, geochemistry and stable isotopes from three lake sediment cores from Øvre ÆrÃ¥svatnet. A total of 23 new dates and age-depth modelling suggests the lake has been ice-free since GI2 (<22.8 k cal. BP) and possibly GS3 (<27.4 k cal. BP). Pinus and Picea sedimentary ancient DNA (sedaDNA) was found in all three cores but at such low frequencies that it could not be distinguished from background contamination. LGM samples have an exceptionally high organic matter content, with isotopic values indicating that carbon and nitrogen derives from a marine source. Along with finds of bones of the little auk (Alle alle), this indicates that the lake received guano from an adjacent bird colony. DNA, pollen and macrofossil assemblages were dominated by Poaceae, Brassicaceae and Papaver, but scattered occurrence of species currently restricted to the Low Arctic Tundra Zone (July temperature of 8-9°C) such as Apiaceae (DNA, 8-9°C), and Alchemilla alpina (macrofossil, 8-9°C) were also recorded. The review showed 94 recorded vascular plant taxa, of which 38% have a northern limit in Shrub Tundra or more southern vegetation zones. This unusual assemblage likely stems from a combination of proximity to ice-free water in summer, geographical isolation linked with stochastic long- distance dispersal events, and the presence of bird-fertilized habitats. The environmental reconstruction based on all records from the area does not preclude local growth of tree species, as the local climate combined with high nutrient input may have led to periodically suitable environmental ‘hotspot’ conditions.",mds,True,findable,188,9,1,1,0,2020-07-07T00:40:48.000Z,2020-07-07T00:40:49.000Z,dryad.dryad,dryad,,,['3353091743 bytes'], +10.5281/zenodo.10429521,cicwi/PyCorrectedEmissionCT: Release version 0.9.0,Zenodo,2023,,Software,Creative Commons Attribution 4.0 International,"New major release, adding quite a few new features and fixing the following bugs: + +Added + + + +QR decomposition for structured illumination + +Background computation function from projection edges + +Basic alignment routines: + + +Simple pre-alignment methods, for projection alignment + +Stack shift tracking, for correcting image drifts + + + +Experimental astra-toolbox backend support (direct FP and BP) + +Basic phase contrast support: + + +Computing and plotting delta-over-beta + +Computing TIE and CTF phase propagation functions + + + +MLEM solver (thanks to J. Lesaint #20) + + +Fixed + + + +Multi-platform pip conda package building + +Type hinting fixes + +Full-field transmission flat-fielding",api,True,findable,0,0,0,0,0,2023-12-24T18:53:58.000Z,2023-12-24T18:53:58.000Z,cern.zenodo,cern,,,, +10.25384/sage.23826552,sj-docx-1-tam-10.1177_17588359231189425 – Supplemental material for Beyond atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma: overall efficacy and safety of tyrosine kinase inhibitors in a real-world setting,SAGE Journals,2023,,Text,Creative Commons Attribution Non Commercial 4.0 International,"Supplemental material, sj-docx-1-tam-10.1177_17588359231189425 for Beyond atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma: overall efficacy and safety of tyrosine kinase inhibitors in a real-world setting by Manon Falette-Puisieux, Jean-Charles Nault, Mohamed Bouattour, Marie Lequoy, Giuliana Amaddeo, Thomas Decaens, Frederic Di Fiore, Sylvain Manfredi, Philippe Merle, Aurore Baron, Christophe Locher, Anna Pellat and Romain Coriat in Therapeutic Advances in Medical Oncology",mds,True,findable,0,0,0,0,0,2023-08-03T00:08:51.000Z,2023-08-03T00:08:51.000Z,figshare.sage,sage,"Oncology and Carcinogenesis not elsewhere classified,Aged Health Care,Pharmacology and Pharmaceutical Sciences not elsewhere classified,Respiratory Diseases","[{'subject': 'Oncology and Carcinogenesis not elsewhere classified'}, {'subject': 'Aged Health Care'}, {'subject': 'Pharmacology and Pharmaceutical Sciences not elsewhere classified'}, {'subject': 'Respiratory Diseases'}]",['13476 Bytes'], +10.5061/dryad.rv0k6,Data from: Inferring skeletal production from time-averaged assemblages: skeletal loss pulls the timing of production pulses towards the modern period,Dryad,2015,en,Dataset,Creative Commons Zero v1.0 Universal,"Age-frequency distributions of dead skeletal material on the landscape or seabed—information on the time that has elapsed since the death of individuals—provide decadal- to millennial-scale perspectives both on the history of production and on the processes that lead to skeletal disintegration and burial. So far, however, models quantifying the dynamics of skeletal loss have assumed that skeletal production is constant during time-averaged accumulation. Here, to improve inferences in conservation paleobiology and historical ecology, we evaluate the joint effects of temporally variable production and skeletal loss on postmortem age-frequency distributions (AFDs) to determine how to detect fluctuations in production over the recent past from AFDs. We show that, relative to the true timing of past production pulses, the modes of AFDs will be shifted to younger age cohorts, causing the true age of past pulses to be underestimated. This shift in the apparent timing of a past pulse in production will be stronger where loss rates are high and/or the rate of decline in production is slow; also, a single pulse coupled with a declining loss rate can, under some circumstances, generate a bimodal distribution. We apply these models to death assemblages of the bivalve Nuculana taphria from the Southern California continental shelf, finding that: (1) an onshore-offshore gradient in time averaging is dominated by a gradient in the timing of production, reflecting the tracking of shallow-water habitats under a sea-level rise, rather than by a gradient in disintegration and sequestration rates, which remain constant with water depth; and (2) loss-corrected model-based estimates of the timing of past production are in good agreement with likely past changes in local production based on an independent sea-level curve.",mds,True,findable,435,38,1,2,0,2015-06-10T14:22:26.000Z,2015-06-10T14:22:27.000Z,dryad.dryad,dryad,"Amino acid racemization,Diagenesis,Radiocarbon,Bivalvia,Nuculana,Time averaging,Holocene","[{'subject': 'Amino acid racemization'}, {'subject': 'Diagenesis'}, {'subject': 'Radiocarbon'}, {'subject': 'Bivalvia'}, {'subject': 'Nuculana'}, {'subject': 'Time averaging'}, {'subject': 'Holocene'}]",['923317 bytes'], +10.6084/m9.figshare.c.6252814.v1,Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data,figshare,2022,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Outcomes of postresuscitation shock after cardiac arrest can be affected by targeted temperature management (TTM). A post hoc analysis of the “TTM1 trial†suggested higher mortality with hypothermia at 33 °C. We performed a post hoc analysis of HYPERION trial data to assess potential associations linking postresuscitation shock after non-shockable cardiac arrest to hypothermia at 33 °C on favourable functional outcome. Methods We divided the patients into groups with vs. without postresuscitation (defined as the need for vasoactive drugs) shock then assessed the proportion of patients with a favourable functional outcome (day-90 Cerebral Performance Category [CPC] 1 or 2) after hypothermia (33 °C) vs. controlled normothermia (37 °C) in each group. Patients with norepinephrine or epinephrine > 1 µg/kg/min were not included. Results Of the 581 patients included in 25 ICUs in France and who did not withdraw consent, 339 had a postresuscitation shock and 242 did not. In the postresuscitation-shock group, 159 received hypothermia, including 14 with a day-90 CPC of 1–2, and 180 normothermia, including 10 with a day-90 CPC of 1–2 (8.81% vs. 5.56%, respectively; P = 0.24). After adjustment, the proportion of patients with CPC 1–2 also did not differ significantly between the hypothermia and normothermia groups (adjusted hazards ratio, 1.99; 95% confidence interval, 0.72–5.50; P = 0.18). Day-90 mortality was comparable in these two groups (83% vs. 86%, respectively; P = 0.43). Conclusions After non-shockable cardiac arrest, mild-to-moderate postresuscitation shock at intensive-care-unit admission did not seem associated with day-90 functional outcome or survival. Therapeutic hypothermia at 33 °C was not associated with worse outcomes compared to controlled normothermia in patients with postresuscitation shock. Trial registration ClinicalTrials.gov, NCT01994772",mds,True,findable,0,0,0,0,0,2022-10-18T03:24:07.000Z,2022-10-18T03:24:07.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Physiology,FOS: Biological sciences,Pharmacology,Biotechnology,Cancer,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Physiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}]",, +10.25384/sage.21845348.v1,sj-doc-1-acr-10.1177_02841851221138519 - Supplemental material for Validation of a screening algorithm for hepatic fibrosis by Doppler ultrasound and elastography in a general population,SAGE Journals,2023,,Text,In Copyright,"Supplemental material, sj-doc-1-acr-10.1177_02841851221138519 for Validation of a screening algorithm for hepatic fibrosis by Doppler ultrasound and elastography in a general population by Anne-Sophie Renard, Anita Paisant, Victoire Cartier, Paul Calès, Mirela Goyet-Prelipcean, Edmond Geagea, Jean-Pierre Tasu, Christine Silvain, Mathilde Wagner, Aline Le Cleach, Valérie Vilgrain, Laurent Castera, Ivan Bricault, Thomas Decaens, Céline Savoye-Collet, Hélène Montialoux, Jean-Michel Correas, Anaïs Vallet-Pichard, Jérôme Boursier and Christophe Aubé in Acta Radiologica",mds,True,findable,0,0,0,0,0,2023-01-10T01:14:28.000Z,2023-01-10T01:14:28.000Z,figshare.sage,sage,"110320 Radiology and Organ Imaging,FOS: Clinical medicine","[{'subject': '110320 Radiology and Organ Imaging', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['36864 Bytes'], +10.48380/zc5e-4m51,Insight into formation of hydrothermal ore deposits using a hydrothermal autoclave and X-ray absorption spectroscopy,Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV),2022,en,Text,,"<p>Hydrothermal fluids play an important role during the formation of most economically explored ore deposits. While cycling through the crust these supercritical fluids efficiently dissolve and transport metals from the source rocks; metal-rich minerals precipitate on their way towards the Earth’s surface. In general, compositions of hydrothermal ore fluids are well known, e.g., by analyzing fluid inclusions in ore minerals. However, because sources and physiochemical characteristics of hydrothermal fluids vary widely, complexation and speciation of metals in the fluid and precipitation mechanisms of ore minerals are still matter of controversial debates. Conclusions on metal complexation and speciation in the fluids are usually based on analysis of quench experiments that do not consider the probably non-quenchable nature of hydrothermal metal complexes e.g., as previously reported for gold (Pokrovski et al., 2015). Thus, reliable information on metal complexation and speciation during ore deposit formation can only be obtained using in-situ data. </p> +<p>Here, we present an autoclave dedicated to in-situ characterization of hydrothermal fluids at high pressures and temperatures at Deutsches Elektronen-Synchrotron (Klemme et al., 2021). Besides discussing details of the experimental set-up we will also focus on results of two ongoing projects dedicated to formation of W and Sn hydrothermal ore deposits. </p> +<p>G. Pokrovski et al., PNAS 112 (44), 2015; Klemme et al., Rev Sci Instr, 92, 2021</p> +<p>Funding: Bundesministerium für Bildung und Forschung (BMBF) grant FKZ 05K16PMA, DESY Center for Molecular Water Science - Early Science Project.</p> +",api,True,findable,0,0,0,0,0,2023-05-31T14:12:43.000Z,2023-05-31T14:12:43.000Z,mcdy.dohrmi,mcdy,,,, +10.6084/m9.figshare.21368764.v1,Additional file 1 of Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Table S3. Summary of the updated 2022 guidelines for AMI: statements and recommendations.,mds,True,findable,0,0,0,0,0,2022-10-20T06:32:08.000Z,2022-10-20T06:32:09.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Neuroscience,Biotechnology,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Neuroscience'}, {'subject': 'Biotechnology'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['26216 Bytes'], +10.6084/m9.figshare.22599664.v1,Additional file 2 of Procalcitonin to reduce exposure to antibiotics and individualise treatment in hospitalised old patients with pneumonia: a randomised study,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 2.,mds,True,findable,0,0,0,0,0,2023-04-13T09:42:55.000Z,2023-04-13T09:42:56.000Z,figshare.ars,otjm,"Space Science,Medicine,Immunology,FOS: Clinical medicine,Cancer,111714 Mental Health,FOS: Health sciences,110309 Infectious Diseases","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '110309 Infectious Diseases', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}]",['286856 Bytes'], +10.6084/m9.figshare.23994601,Additional file 1 of Determination of different social groups’ level of knowledge about malaria in a multicultural Amazonian cross-border context,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Appendix 1. Factor analyses of multiple-choice variables assessing knowledge of symptoms.,mds,True,findable,0,0,0,0,0,2023-08-20T03:11:01.000Z,2023-08-20T03:11:01.000Z,figshare.ars,otjm,"Biological Sciences not elsewhere classified,Science Policy","[{'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Science Policy'}]",['19713 Bytes'], +10.6084/m9.figshare.24030816.v1,Additional file 1 of Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1. Supplementary tables S1-S6 and supplemtary figures S1-S6.,mds,True,findable,0,0,0,0,0,2023-08-25T03:21:17.000Z,2023-08-25T03:21:17.000Z,figshare.ars,otjm,"Medicine,Biotechnology,Immunology,FOS: Clinical medicine,Biological Sciences not elsewhere classified,Cancer,Science Policy,Mental Health,Infectious Diseases,FOS: Health sciences,Virology","[{'subject': 'Medicine'}, {'subject': 'Biotechnology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}, {'subject': 'Mental Health'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Virology'}]",['680816 Bytes'], +10.6084/m9.figshare.22599664,Additional file 2 of Procalcitonin to reduce exposure to antibiotics and individualise treatment in hospitalised old patients with pneumonia: a randomised study,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 2.,mds,True,findable,0,0,0,0,0,2023-04-13T09:42:55.000Z,2023-04-13T09:42:56.000Z,figshare.ars,otjm,"Space Science,Medicine,Immunology,FOS: Clinical medicine,Cancer,111714 Mental Health,FOS: Health sciences,110309 Infectious Diseases","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '110309 Infectious Diseases', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}]",['286856 Bytes'], +10.5061/dryad.6gc6h,Data from: Development of an Arabis alpina genomic contig sequence dataset and application to single nucleotide polymorphisms discovery,Dryad,2013,en,Dataset,Creative Commons Zero v1.0 Universal,"The alpine plant Arabis alpina is an emerging model in the ecological genomic field which is well-suited to identifying the genes involved in local adaptation in contrasted environmental conditions, a subject which remains poorly understood at molecular level. This paper presents the assembly of a pool of A. alpina genomic fragments using Next Generation Sequencing technologies. These contigs cover 172 Mb of the A. alpina genome (i.e. 50% of the genome) and were shown to contain sequences giving positive hits against 96% of the 458 CEGMA core genes (Core Eukaryotic Genes Mapping Approach), a set of highly conserved eukaryotic genes. Regions presenting high nucleic sequence identity with 77% of the close relative Arabidopsis thaliana's genes were found, with an unbiased distribution across the different functional categories of A. thaliana genes. This new resource was tested using a resequencing assay to identify polymorphic sites. Sixteen samples were successfully analyzed and 127,041 Single Nucleotide Polymorphisms identified. This contig dataset will contribute to improving understanding of the ecology of Arabis alpina, thus constituting an important resource for future ecological genomic studies.",mds,True,findable,601,179,1,1,0,2013-10-14T14:23:52.000Z,2013-10-14T14:23:54.000Z,dryad.dryad,dryad,"Genomics/Proteomics,Bioinfomatics/Phyloinfomatics","[{'subject': 'Genomics/Proteomics'}, {'subject': 'Bioinfomatics/Phyloinfomatics'}]",['611063794 bytes'], +10.6084/m9.figshare.c.6910186.v1,Cefoxitin versus carbapenems as definitive treatment for extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteremia in intensive care unit: a propensity-matched retrospective analysis,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Despite cefoxitin's in vitro resistance to hydrolysis by extended-spectrum beta-lactamases (ESBL), treatment of ESBL-producing Klebsiella pneumoniae (KP) infections with cefoxitin remains controversial. The aim of our study was to compare the clinical efficacy of cefoxitin as definitive antibiotic therapy for patients with ESBL-KP bacteremia in intensive care unit, versus carbapenem therapy. Methods This retrospective study included all patients with monomicrobial bacteremia hospitalized in intensive care unit between January 2013 and January 2023 at the University Hospital of Guadeloupe. The primary outcome was the 30-day clinical success defined as a composite endpoint: 30-day survival, absence of relapse and no change of antibiotic therapy. Cox regression including a propensity score (PS) and PS-based matched analysis were performed for endpoint analysis. Results A total of 110 patients with bloodstream infections were enrolled. Sixty-three patients (57%) received definitive antibiotic therapy with cefoxitin, while forty-seven (43%) were treated with carbapenems. 30-day clinical success was not significantly different between patients treated with cefoxitin (57%) and carbapenems (53%, p = 0.823). PS-adjusted and PS-matched analysis confirmed these findings. Change of definitive antibiotic therapy was more frequent in the cefoxitin group (17% vs. 0%, p = 0.002). No significant differences were observed for the other secondary endpoints. The acquisition of carbapenem-resistant Pseudomonas aeruginosa was significantly higher in patients receiving carbapenem therapy (5% vs. 23%, p = 0.007). Conclusions Our results suggest that cefoxitin as definitive antibiotic therapy could be a therapeutic option for some ESBL-KP bacteremia, sparing carbapenems and reducing the selection of carbapenem-resistant Pseudomonas aeruginosa strains.",mds,True,findable,0,0,0,0,0,2023-11-02T05:33:24.000Z,2023-11-02T05:33:25.000Z,figshare.ars,otjm,"Space Science,Medicine,Microbiology,FOS: Biological sciences,Cancer,Infectious Diseases,FOS: Health sciences","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Microbiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.22625614.v1,"Additional file 3 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 3.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:15.000Z,2023-04-13T18:48:16.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['359400 Bytes'], +10.6084/m9.figshare.24091567,Additional file 2 of Survey of adolescents’ needs and parents’ views on sexual health in juvenile idiopathic arthritis,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary Material 2,mds,True,findable,0,0,0,0,0,2023-09-06T17:23:04.000Z,2023-09-06T17:23:04.000Z,figshare.ars,otjm,"Medicine,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}]",['286208 Bytes'], +10.5061/dryad.1jwstqk1p,"Data for: Reproductive tactics, birth timing and the risk-resource trade-off in an income breeder",Dryad,2023,en,Dataset,Creative Commons Zero v1.0 Universal,"In variable environments, habitats that are rich in resources often carry a higher risk of predation. As a result, natural selection should favour individuals that balance allocation of time to foraging versus avoiding predation through an optimal decision-making process that maximises fitness. The behavioural trade-off between resource acquisition and risk avoidance is expected to be particularly acute during gestation and lactation when the energetic demands of reproduction peak. Here, we investigated how reproductive female roe deer adjust their foraging activity and habitat use during the birth period to manage this trade-off compared to non-reproductive juveniles, and how parturition date constrains individual tactics of risk-resource management. Activity of reproductive females more than doubled immediately following parturition, when energy demand is highest. Furthermore, compared to non-reproductive juveniles, they increased their exposure to risk by using open habitat more during daytime and ranging closer to roads. However, these post-partum modifications in behaviour were particularly pronounced in late-parturient females who adopted a more risk-prone tactic, presumably to compensate for the growth handicap of their late-born offspring. In income breeders, individuals that give birth late may be constrained to trade risk avoidance for foraging during peak allocation to reproduction, with probable consequences for individual fitness.",mds,True,findable,27,3,0,1,0,2023-10-20T15:40:53.000Z,2023-10-20T15:40:54.000Z,dryad.dryad,dryad,"roe deer,Activity data,Spatial Data,FOS: Biological sciences,FOS: Biological sciences","[{'subject': 'roe deer'}, {'subject': 'Activity data'}, {'subject': 'Spatial Data'}, {'subject': 'FOS: Biological sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['3881585 bytes'], +10.6084/m9.figshare.22620040,"Additional file 4 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 4: NOS3 homozygous splice variant in M084 and NOS3 homozygous missense variant in M035.,mds,True,findable,0,0,0,0,0,2023-04-13T14:39:30.000Z,2023-04-13T16:07:50.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['286190 Bytes'], +10.6084/m9.figshare.22625629,"Additional file 8 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 8.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:16.000Z,2023-04-13T18:56:16.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['984563 Bytes'], +10.6084/m9.figshare.c.6596467,"A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Immunosuppression after kidney transplantation is mainly guided via plasma tacrolimus trough level, which cannot sufficiently predict allograft rejection and infection. The plasma load of the non-pathogenic and highly prevalent torque teno virus (TTV) is associated with the immunosuppression of its host. Non-interventional studies suggest the use of TTV load to predict allograft rejection and infection. The primary objective of the current trial is to demonstrate the safety, tolerability and preliminary efficacy of TTV-guided immunosuppression. Methods For this purpose, a randomised, controlled, interventional, two-arm, non-inferiority, patient- and assessor-blinded, investigator-driven phase II trial was designed. A total of 260 stable, low-immunological-risk adult recipients of a kidney graft with tacrolimus-based immunosuppression and TTV infection after month 3 post-transplantation will be recruited in 13 academic centres in six European countries. Subjects will be randomised in a 1:1 ratio (allocation concealment) to receive tacrolimus either guided by TTV load or according to the local centre standard for 9 months. The primary composite endpoint includes the occurrence of infections, biopsy-proven allograft rejection, graft loss, or death. The main secondary endpoints include estimated glomerular filtration rate, graft rejection detected by protocol biopsy at month 12 post-transplantation (including molecular microscopy), development of de novo donor-specific antibodies, health-related quality of life, and drug adherence. In parallel, a comprehensive biobank will be established including plasma, serum, urine and whole blood. The date of the first enrolment was August 2022 and the planned end is April 2025. Discussion The assessment of individual kidney transplant recipient immune function might enable clinicians to personalise immunosuppression, thereby reducing infection and rejection. Moreover, the trial might act as a proof of principle for TTV-guided immunosuppression and thus pave the way for broader clinical applications, including as guidance for immune modulators or disease-modifying agents. Trial registration EU CT-Number: 2022-500024-30-00",mds,True,findable,0,0,0,0,0,2023-04-13T16:10:08.000Z,2023-04-13T17:26:49.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.5281/zenodo.10214410,Radiofrequency to Microwave Coherent Manipulation of an Organometallic Electronic Spin Qubit Coupled to a Nuclear Qudit,Zenodo,2021,,Dataset,Creative Commons Attribution 4.0 International,"Dataset containing ASCII files for Figures 2-8 of the paper +Radiofrequency to Microwave Coherent Manipulation of an Organometallic Electronic Spin Qubit Coupled to a Nuclear Qudit +Inorg. Chem. 2021, 60, 11273−11286",api,True,findable,0,0,0,0,0,2023-11-29T12:01:19.000Z,2023-11-29T12:01:19.000Z,cern.zenodo,cern,,,, +10.5061/dryad.bcc2fqz79,Data from: Unveiling the food webs of tetrapods across Europe through the prism of the Eltonian niche,Dryad,2020,en,Dataset,Creative Commons Zero v1.0 Universal,"Aim Despite the recent calls on integrating the interaction networks into the study of largeâ€scale biodiversity patterns, we still lack a basic understanding of the functional characteristics of large interaction networks and how they are structured across environments. Here, building on recent advances in network science around the Eltonian niche concept, we aim to characterize the trophic groups in a large food web, and understand how these trophic groups vary across space. Location Europe and Anatolia. Taxon Tetrapods (1,136 species). Methods We combined an expertâ€based metaweb of all European tetrapods with their spatial distributions and biological traits. To understand the functional structure of the metaweb, we first used a stochastic block model to group species with similar Eltonian niches, and then analysed these groups with species’ functional traits and network metrics. We then combined these groups with species distributions to understand how trophic diversity varies across space, in function of the environment, and between the European ecoregions. Results We summarized the 1,136 interacting species within the metaweb into 46 meaningful trophic groups of species with a similar role in the metaweb. Specific aspects of the ecology of species, such as their activity time, nesting habitat and diet explained these trophic groups. Across space, trophic diversity was driven by both biotic and abiotic factors (species richness, climate and primary productivity), and the representation of trophic groups differed among European ecoregions. Main conclusions We have characterized the Eltonian niche of species in a large food web, both in terms of species interactions and functional traits, and then using this to understand the spatial variation of food webs at a functional level, thus bringing together network science, functional ecology and biogeography. Our results highlight the need to integrate multiple aspects of species ecology in global change research. Further, our approach is strongly relevant for conservation biology as it could help predict the impact of species translocations on trophic diversity.",mds,True,findable,341,28,0,0,0,2019-12-06T17:21:08.000Z,2019-12-06T17:21:09.000Z,dryad.dryad,dryad,"metaweb,stochastic block model,Trophic diversity,trophic groups","[{'subject': 'metaweb'}, {'subject': 'stochastic block model'}, {'subject': 'Trophic diversity'}, {'subject': 'trophic groups'}]",['2823551 bytes'], +10.5281/zenodo.10436474,NeoGeographyToolkit/StereoPipeline: 2023-12-27-daily-build,Zenodo,2023,,Software,Creative Commons Attribution 4.0 International,Recent additions log: https://stereopipeline.readthedocs.io/en/latest/news.html,api,True,findable,0,0,0,0,0,2023-12-27T18:22:40.000Z,2023-12-27T18:22:40.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.23816832,Supplementary document for Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃ - 6551122.pdf,Optica Publishing Group,2023,,Text,Creative Commons Attribution 4.0 International,Supplemental document.,mds,True,findable,0,0,0,0,0,2023-08-01T16:29:43.000Z,2023-09-01T15:03:20.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],['11379174 Bytes'], +10.17632/s62jkk3fkt.1,ACTi graphs: Datasets of physiological experiments associated with measurement on stress and energy expenditure,Mendeley Data,2023,,Dataset,Creative Commons Attribution 4.0 International,"The database presented combines the data from the ActiGraphs worn by the test participants. During these tests, the participants wore three ActiGraphs placed on their ankle, waist and wrist. The published data is pre-processed data that has been processed in the ActiLife software. This database made it possible to compare energy expenditure with the number of mistakes made and with the participants' perception of stress. The data is divided into folders, with each folder referring to a participant. Within each participant folder there are three folders and a file. Each folder stores the pre-processed data from the ACTiGraphs and is divided by the body zones where the sensors are placed (ankle, waist and wrist). The ""performance.xlsx"" file details the participant's performance during the test. The pre-processed ACTiGraphs files show the counts of the sensor axis. These counts are calculated by the ACTiLife software, and the method of calculation is something that the company does not make public. There is also other information in these files, such as the indication of inclinometers and step counts, data that was not used in this study. The ""performace.xlsx"" file describes the conditions and results of the tasks that each participant had to carry out. It details the start and end time of each task, the number of errors made while performing the task, and the environmental and noise conditions (""Temperature"" and ""Noise""). This file also records the answers to a stress questionnaire that was applied at the end of each task. This questionnaire can be found in the attached documents under ""Stress Questionnaire.pdf"".",api,True,findable,0,0,0,0,0,2023-11-16T02:41:13.000Z,2023-11-16T02:41:14.000Z,bl.mendeley,elsevier,"Ergonomics,Occupational Stress,Physical Stress,Perceived Stress","[{'subject': 'Ergonomics'}, {'subject': 'Occupational Stress'}, {'subject': 'Physical Stress'}, {'subject': 'Perceived Stress'}]",, +10.5281/zenodo.10410541,The Arabidopsis Leaf Quantitative Atlas: a cellular and subcellular mapping through unified data integration,Zenodo,2023,,Dataset,Creative Commons Attribution 4.0 International,"Additional data accompanying Tolleter et. al. The Arabidopsis Leaf Quantitative Atlas: a cellular and subcellular mapping through unified data integration Quantitative Plant Biology. 2024. + +Quantitative analyses and models are required to connect a plant's cellular organization with its metabolism. However, quantitative data are often scattered over multiple studies, and finding such data and converting them into useful information is time consuming. Consequently, there is a need to centralize the available data and to highlight the remaining knowledge gaps. Here, we present a step-by-step approach to manually extract quantitative data from various information sources, and to unify the data format. First, data from Arabidopsis leaf were collated, checked for consistency and correctness, and curated by cross-checking sources. Second, quantitative data were combined by applying calculation rules. They were then integrated into a unique comprehensive, referenced, modifiable and reusable data compendium representing an Arabidopsis reference leaf. This atlas contains the metrics of the 15 cell types found in leaves at the cellular and subcellular levels. + +Table_S1_2023_12_12.xlsx: All supplementary data relating to the Arabidopsis Leaf Quantitative Atlas + +ChloroKB data export.ipynb: A jupyter notebook containing code to convert Quantitative_data_2023_12_13.xlsx (from http://umr5558-chlorokb.univ-lyon1.fr:8080/ChloroKB_Grails/static/images/csv/Quantitative_data.csv) into Table_S5_2023_12_13.xlsx. + +Variable_conversion_table.xlsx ,Localisation_conversion_table.xlsx, Localisation_conversion_table_isolated_organelles.xlsx: Conversion factors required by ChloroKB data export.ipynb for unit conversion. ",api,True,findable,0,0,0,0,0,2023-12-22T09:20:50.000Z,2023-12-22T09:20:50.000Z,cern.zenodo,cern,,,, +10.5061/dryad.ff138,Data from: Contrasting microbial biogeographical patterns between anthropogenic subalpine grasslands and natural alpine grasslands,Dryad,2016,en,Dataset,Creative Commons Zero v1.0 Universal,"The effect of plant species composition on soil microbial communities was studied at the multiregional level. We compared the soil microbial communities of alpine natural grasslands dominated by Carex curvula and anthropogenic subalpine pastures dominated by Nardus stricta. We conducted paired sampling across the Carpathians and the Alps and used Illumina sequencing to reveal the molecular diversity of soil microbes. We found that bacterial and fungal communities exhibited contrasting regional distributions and that the distribution in each grassland is well discriminated. Beta diversity of microbial communities was much higher in C. curvula grasslands due to a marked regional effect. The composition of grassland-type core microbiomes suggest that C. curvula, and N. stricta to a lesser extent, tend to select a cohort of microbes related to antibiosis/exclusion, pathogenesis and endophytism. We discuss these findings in light of the postglacial history of the studied grasslands, the habitat connectivity and the disturbance regimes. Human-induced disturbance in the subalpine belt of European mountains has led to homogeneous soil microbial communities at large biogeographical scales. Our results confirm the overarching role of the dominant grassland plant species in the distribution of microbial communities and highlight the relevance of biogeographical history.",mds,True,findable,340,77,1,1,0,2015-09-01T13:45:21.000Z,2015-09-01T13:45:23.000Z,dryad.dryad,dryad,"core-community,Post-glacial period,alpine ecosystems,bacterial and fungal soil diversity,mountain grasslands,microbial biogeography,biotrophic fungi,keystone species.","[{'subject': 'core-community'}, {'subject': 'Post-glacial period'}, {'subject': 'alpine ecosystems'}, {'subject': 'bacterial and fungal soil diversity'}, {'subject': 'mountain grasslands'}, {'subject': 'microbial biogeography'}, {'subject': 'biotrophic fungi'}, {'subject': 'keystone species.'}]",['103159872 bytes'], +10.5061/dryad.q573n5tm6,Data from: Energy and physiological tolerance explain multi-trophic soil diversity in temperate mountains,Dryad,2022,en,Dataset,Creative Commons Zero v1.0 Universal,"Aim – Although soil biodiversity is extremely rich and spatially variable, both in terms of species and trophic groups, we still know little about its main drivers. Here, we contrast four long-standing hypotheses to explain the spatial variation of soil multi-trophic diversity: energy, physiological tolerance, habitat heterogeneity, and resource heterogeneity. Location – French Alps Methods – We built on a large-scale observatory across the French Alps (Orchamp) made of seventeen elevational gradients (~90 plots) ranging from low to very high altitude (280 - 3160 m), and encompassing large variations in climate, vegetation and pedological conditions. Biodiversity measurements of 36 soil trophic groups were obtained through environmental DNA metabarcoding. Using a machine learning approach, we assessed 1) the relative importance of predictors linked to different ecological hypotheses in explaining overall multi-trophic soil biodiversity, and 2) the consistency of the response curves across trophic groups. Results – We showed that predictors associated with the four hypotheses had a statistically significant influence on soil multi-trophic diversity, with the strongest support for the energy and physiological tolerance hypotheses. Physiological tolerance explained spatial variation in soil diversity consistently across trophic groups, and was an especially strong predictor for bacteria, protists and microfauna. The effect of energy was more group-specific, with energy input through soil organic matter strongly affecting groups related to the detritus channel. Habitat and resource heterogeneity had overall weaker and more specific impacts on biodiversity with habitat heterogeneity affecting mostly autotrophs, and resource heterogeneity affecting bacterivores, phytophagous insects, enchytraeids and saprotrophic fungi. Main Conclusions – Despite the variability of responses to the environmental drivers found across soil trophic groups, major commonalities on the ecological processes structuring soil biodiversity emerged. We conclude that among the major ecological hypotheses traditionally applied to aboveground organisms, some are particularly relevant to predict the spatial variation in soil biodiversity across the major soil trophic groups.",mds,True,findable,137,14,0,0,0,2022-03-25T18:17:21.000Z,2022-03-25T18:17:22.000Z,dryad.dryad,dryad,"FOS: Biological sciences,FOS: Biological sciences","[{'subject': 'FOS: Biological sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['9894066 bytes'], +10.6084/m9.figshare.22620037.v1,"Additional file 3 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 3: Candidate homozygous variants identified in the 6 consanguineous probands.,mds,True,findable,0,0,0,0,0,2023-04-13T14:40:01.000Z,2023-04-13T15:25:49.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['28253 Bytes'], +10.6084/m9.figshare.22625623,"Additional file 6 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 6.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:19.000Z,2023-04-13T18:56:20.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['190912 Bytes'], +10.6084/m9.figshare.c.6424523.v1,Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃,Optica Publishing Group,2023,,Collection,Creative Commons Attribution 4.0 International,"By performing Bidirectionnal Reflectance Distribution Function (BRDF) measurements, we have identified back-scattering as the main phenomena involved in the appearance of dry nano-crystallized powders. We introduce an analytical and physically-based BRDF model that relies on the enhanced back-scattering theory to accurately reproduce BRDF measurements. These experimental data were performed on optically thick layers of dry powders with various grains’ morphologies. Our results are significantly better than the ones obtained with previous models. Our model has been validated against the BRDF measurements of multiple synthesized nano-crystallized and mono-disperse 𛼠− Fe2O3 hematite powders. Finally, we discuss the ability of our model to be extended to other materials or more complex powder morphologies.",mds,True,findable,0,0,0,0,0,2023-09-01T15:03:20.000Z,2023-09-01T15:03:21.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],, +10.6084/m9.figshare.c.6257914,Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery,figshare,2022,,Collection,Creative Commons Attribution 4.0 International,"Abstract Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09–0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains in the range of 50%. Early diagnosis and timely surgical intervention are the cornerstones of modern treatment to reduce the high mortality associated with this entity. The advent of endovascular approaches in parallel with modern imaging techniques is evolving and provides new treatment options. Lastly, a focused multidisciplinary approach based on early diagnosis and individualized treatment is essential. Thus, we believe that updated guidelines from World Society of Emergency Surgery are warranted, in order to provide the most recent and practical recommendations for diagnosis and treatment of AMI.",mds,True,findable,0,0,0,0,0,2022-10-20T06:32:09.000Z,2022-10-20T06:32:09.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Neuroscience,Biotechnology,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Neuroscience'}, {'subject': 'Biotechnology'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.21368764,Additional file 1 of Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Table S3. Summary of the updated 2022 guidelines for AMI: statements and recommendations.,mds,True,findable,0,0,0,0,0,2022-10-20T06:32:08.000Z,2022-10-20T06:32:09.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Neuroscience,Biotechnology,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Neuroscience'}, {'subject': 'Biotechnology'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['26216 Bytes'], +10.6084/m9.figshare.22075664.v2,Supplementary document for Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃ - 6292687.pdf,Optica Publishing Group,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary model information and results,mds,True,findable,0,0,0,0,0,2023-09-01T15:04:44.000Z,2023-09-01T15:04:45.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],['14116626 Bytes'], +10.6084/m9.figshare.22620031,"Additional file 1 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Genealogical trees of to the 6 consanguineous MMA probands.,mds,True,findable,0,0,0,0,0,2023-04-13T14:39:34.000Z,2023-04-13T14:40:09.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['134635 Bytes'], +10.6084/m9.figshare.c.6821914,Survey of adolescents’ needs and parents’ views on sexual health in juvenile idiopathic arthritis,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Although the advent of new therapeutics for juvenile idiopathic arthritis (JIA) patients has considerably lessened the impact of the disease and reduced its sequelae, the outcomes of JIA remain important in their lives. Disease repercussions and side effects of treatments may affect sexual health and cause psychological distress. This aim of the study was to determine the expectations of adolescent JIA patients and the perceptions of their parents regarding knowledge and communication with healthcare providers (HCPs) in the field of sexual health (SH). Methods In France, from September 2021 to April 2022, a survey was conducted, using anonymous self-administered questionnaires, among JIA patients (adults (aged 18–45 years) to provide insights from their recollection of their adolescence) and their parents in nine rheumatology centers and three patient associations. Results The responses to the 76 patient questionnaires and 43 parent questionnaires that were collected were analyzed. Half of the patients thought JIA impacted their romantic relationships, but the results were less clear-cut for their sexual activity; and 58.7% of the patients said they would be comfortable discussing the subject with HCPs, but only 26.3% had done so, mainly regarding biomedical issues. The patients and their parents thought that ideally, the topic should be addressed in an individual patient education session at the hospital (51.3% and 34.9%, respectively), in a regular consultation (47.4% and 53.5%), or in a dedicated consultation requested by the adolescent without the adolescent’s parents being informed (38.2% and 20.9%). Most of the respondents thought HCPs should be proactive in SH (77.6% of the patients and 69.8% of their parents). More patients than parents said the following digital information tools must be used: videos (29.0% vs. 9.3%, p = 0.0127) and smartphone applications (25.0% vs. 9.3%, p = 0.0372). Conclusion HCPs should consider addressing the unmet need for SH discussions during their patient encounters. To meet this need, we propose concrete actions in line with the wishes of patients and parents. Clinical trial registration number NCT04791189.",mds,True,findable,0,0,0,0,0,2023-09-06T17:22:59.000Z,2023-09-06T17:22:59.000Z,figshare.ars,otjm,"Medicine,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}]",, +10.6084/m9.figshare.20080019.v5,Views Evolution 5 Minutes Frequency,figshare,2022,,Dataset,Creative Commons Attribution 4.0 International,"This dataset contains 1934 videos posted between February 2, 2022 and February 16, 2022. For every video it records the amount of views every 5 minutes.",mds,True,findable,0,0,0,0,0,2022-11-24T11:54:59.000Z,2022-11-24T11:54:59.000Z,figshare.ars,otjm,"Applications in physical sciences,Complex physical systems","[{'subject': 'Applications in physical sciences'}, {'subject': 'Complex physical systems'}]",['352821547 Bytes'], +10.6084/m9.figshare.c.6910186,Cefoxitin versus carbapenems as definitive treatment for extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteremia in intensive care unit: a propensity-matched retrospective analysis,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Despite cefoxitin's in vitro resistance to hydrolysis by extended-spectrum beta-lactamases (ESBL), treatment of ESBL-producing Klebsiella pneumoniae (KP) infections with cefoxitin remains controversial. The aim of our study was to compare the clinical efficacy of cefoxitin as definitive antibiotic therapy for patients with ESBL-KP bacteremia in intensive care unit, versus carbapenem therapy. Methods This retrospective study included all patients with monomicrobial bacteremia hospitalized in intensive care unit between January 2013 and January 2023 at the University Hospital of Guadeloupe. The primary outcome was the 30-day clinical success defined as a composite endpoint: 30-day survival, absence of relapse and no change of antibiotic therapy. Cox regression including a propensity score (PS) and PS-based matched analysis were performed for endpoint analysis. Results A total of 110 patients with bloodstream infections were enrolled. Sixty-three patients (57%) received definitive antibiotic therapy with cefoxitin, while forty-seven (43%) were treated with carbapenems. 30-day clinical success was not significantly different between patients treated with cefoxitin (57%) and carbapenems (53%, p = 0.823). PS-adjusted and PS-matched analysis confirmed these findings. Change of definitive antibiotic therapy was more frequent in the cefoxitin group (17% vs. 0%, p = 0.002). No significant differences were observed for the other secondary endpoints. The acquisition of carbapenem-resistant Pseudomonas aeruginosa was significantly higher in patients receiving carbapenem therapy (5% vs. 23%, p = 0.007). Conclusions Our results suggest that cefoxitin as definitive antibiotic therapy could be a therapeutic option for some ESBL-KP bacteremia, sparing carbapenems and reducing the selection of carbapenem-resistant Pseudomonas aeruginosa strains.",mds,True,findable,0,0,0,0,0,2023-11-02T05:00:07.000Z,2023-11-02T05:00:08.000Z,figshare.ars,otjm,"Space Science,Medicine,Microbiology,FOS: Biological sciences,Cancer,Infectious Diseases,FOS: Health sciences","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Microbiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.5061/dryad.03mn0,Data from: Conserved G-matrices of morphological and life-history traits among continental and island blue tit populations,Dryad,2017,en,Dataset,Creative Commons Zero v1.0 Universal,"The genetic variance–covariance matrix (G-matrix) summarizes the genetic architecture of multiple traits. It has a central role in the understanding of phenotypic divergence and the quantification of the evolutionary potential of populations. Laboratory experiments have shown that G-matrices can vary rapidly under divergent selective pressures. However, because of the demanding nature of G-matrix estimation and comparison in wild populations, the extent of its spatial variability remains largely unknown. In this study, we investigate spatial variation in G-matrices for morphological and life-history traits using long-term data sets from one continental and three island populations of blue tit (Cyanistes caeruleus) that have experienced contrasting population history and selective environment. We found no evidence for differences in G-matrices among populations. Interestingly, the phenotypic variance–covariance matrices (P) were divergent across populations, suggesting that using P as a substitute for G may be inadequate. These analyses also provide the first evidence in wild populations for additive genetic variation in the incubation period (that is, the period between last egg laid and hatching) in all four populations. Altogether, our results suggest that G-matrices may be stable across populations inhabiting contrasted environments, therefore challenging the results of previous simulation studies and laboratory experiments.",mds,True,findable,266,19,1,2,0,2017-02-20T14:31:25.000Z,2017-02-20T14:31:26.000Z,dryad.dryad,dryad,,,['605722 bytes'], +10.6084/m9.figshare.22620034,"Additional file 2 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 2: 3D structural analysis of the functional consequences of the eNOS p.C648R variant and sGC alpha1 subunit p.R593H variant.,mds,True,findable,0,0,0,0,0,2023-04-13T14:39:41.000Z,2023-04-13T16:07:53.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['36825 Bytes'], +10.48380/dggv-jsn0-1k58,Crust and upper mantle structure of the Ligurian Sea revealed by ambient noise tomography and receiver function analysis,Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV),2020,en,Text,,"GEOMAR Helmholtz Centre for Ocean Research Kiel, Germany (1); Kiel University (2); Institut de physique du globe de Paris, Paris, France (3); ISTerre - Institut des Sciences de la Terre, Grenoble, France (4); AlpArray Working Group: http://www.alparray.ethz.ch (5); <br> <br> The Liguro-Provencal-basin was formed as a back-arc basin of the retreating Calabrian-Apennines subduction zone during the Oligocene and Miocene. The resulting rotation of the Corsica-Sardinia block is associated with rifting, shaping the Ligurian Sea. It is debated though, whether oceanic or atypical oceanic crust was formed or if the crust is continental and experienced extreme thinning during the opening of the basin. We contribute to the debate by surveying the type of crust and lithosphere flooring the Ligurian Sea using 29 broadband Ocean Bottom Seismometer (OBS). The instruments were installed in the Ligurian Sea for eight months between June 2017 and February 2018, as part of the AlpArray seismic network. Because of additional noise sources in the ocean, OBS data are rarely used for ambient noise studies. However, we extensively pre-process the data, including corrections for instrument tilt and seafloor compliance, to improve the signal-to-noise ratio. We calculate daily cross-correlation functions for the LOBSTER array and surrounding land stations. Additionally, we correlate short time windows that include strong earthquake events that allow us to derive surface wave group velocities for longer periods than using ambient noise only. Group velocity maps are obtained by inverting Green’s functions derived from the cross-correlation of ambient noise and teleseismic events, respectively. Our group velocity maps show strong heterogeneities for short periods (5-15 s, corresponding to shallow depths). In general, the velocities increase with depth and the velocity anomalies can be related to varying sediment thickness and magmatism. The longer periods (20-90 s) show a smoother velocity structure that reveals mantle velocities in the vicinity of the Ligurian margin, north of the basin centre. However, resolution at greater depth is limited along the Corsican margin due to less station coverage. Our results do not indicate an oceanic spreading centre, however, may hint to an asymmetric opening of the Ligurian Basin.",fabricaForm,True,findable,0,0,0,0,0,2021-01-11T09:10:54.000Z,2021-04-15T11:44:22.000Z,mcdy.dohrmi,mcdy,,,, +10.6084/m9.figshare.22735399,"Additional file 1 of Multiple trauma in pregnant women: injury assessment, fetal radiation exposure and mortality. A multicentre observational study",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary Material 1,mds,True,findable,0,0,0,0,0,2023-05-03T03:19:15.000Z,2023-05-03T03:19:15.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Biotechnology,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Developmental Biology,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Biotechnology'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Developmental Biology'}, {'subject': 'Science Policy'}]",['675112 Bytes'], +10.6084/m9.figshare.22625635.v1,"Additional file 10 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 10.,mds,True,findable,0,0,0,0,0,2023-04-13T18:47:59.000Z,2023-04-13T18:48:00.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['184741 Bytes'], +10.6084/m9.figshare.22625611,"Additional file 2 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 2.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:31.000Z,2023-04-13T18:56:31.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['374370 Bytes'], +10.5061/dryad.t8534,Data from: Long-lasting modification of soil fungal diversity associated with the introduction of rabbits to a remote sub-Antarctic archipelago,Dryad,2015,en,Dataset,Creative Commons Zero v1.0 Universal,"During the late nineteenth century, Europeans introduced rabbits to many of the sub-Antarctic islands, environments that prior to this had been devoid of mammalian herbivores. The impacts of rabbits on indigenous ecosystems are well studied; notably, they cause dramatic changes in plant communities and promote soil erosion. However, the responses of fungal communities to such biotic disturbances remain unexplored. We used metabarcoding of soil extracellular DNA to assess the diversity of plant and fungal communities at sites on the sub-Antarctic Kerguelen Islands with contrasting histories of disturbance by rabbits. Our results suggest that on these islands, the simplification of plant communities and increased erosion resulting from the introduction of rabbits have driven compositional changes, including diversity reductions, in indigenous soil fungal communities. Moreover, there is no indication of recovery at sites from which rabbits were removed 20 years ago. These results imply that introduced herbivores have long-lasting and multifaceted effects on fungal biodiversity as well as highlight the low resiliency of sub-Antarctic ecosystems.",mds,True,findable,363,58,1,1,0,2015-07-28T13:41:40.000Z,2015-07-28T13:41:41.000Z,dryad.dryad,dryad,"Embryophyta,Soil communities","[{'subject': 'Embryophyta'}, {'subject': 'Soil communities'}]",['18033276 bytes'], +10.6084/m9.figshare.c.6596467.v1,"A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Immunosuppression after kidney transplantation is mainly guided via plasma tacrolimus trough level, which cannot sufficiently predict allograft rejection and infection. The plasma load of the non-pathogenic and highly prevalent torque teno virus (TTV) is associated with the immunosuppression of its host. Non-interventional studies suggest the use of TTV load to predict allograft rejection and infection. The primary objective of the current trial is to demonstrate the safety, tolerability and preliminary efficacy of TTV-guided immunosuppression. Methods For this purpose, a randomised, controlled, interventional, two-arm, non-inferiority, patient- and assessor-blinded, investigator-driven phase II trial was designed. A total of 260 stable, low-immunological-risk adult recipients of a kidney graft with tacrolimus-based immunosuppression and TTV infection after month 3 post-transplantation will be recruited in 13 academic centres in six European countries. Subjects will be randomised in a 1:1 ratio (allocation concealment) to receive tacrolimus either guided by TTV load or according to the local centre standard for 9 months. The primary composite endpoint includes the occurrence of infections, biopsy-proven allograft rejection, graft loss, or death. The main secondary endpoints include estimated glomerular filtration rate, graft rejection detected by protocol biopsy at month 12 post-transplantation (including molecular microscopy), development of de novo donor-specific antibodies, health-related quality of life, and drug adherence. In parallel, a comprehensive biobank will be established including plasma, serum, urine and whole blood. The date of the first enrolment was August 2022 and the planned end is April 2025. Discussion The assessment of individual kidney transplant recipient immune function might enable clinicians to personalise immunosuppression, thereby reducing infection and rejection. Moreover, the trial might act as a proof of principle for TTV-guided immunosuppression and thus pave the way for broader clinical applications, including as guidance for immune modulators or disease-modifying agents. Trial registration EU CT-Number: 2022-500024-30-00",mds,True,findable,0,0,0,0,0,2023-04-13T17:22:29.000Z,2023-04-13T17:22:29.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.22625620,"Additional file 5 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 5.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:21.000Z,2023-04-13T18:56:21.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['182300 Bytes'], +10.5061/dryad.qv9s4mwgb,"Root traits, root diameter distribution and soil parameters at the community level along a mediterranean successional gradient",Dryad,2022,en,Dataset,Creative Commons Zero v1.0 Universal,"The data correspond to average root traits at the community level, and parameters describing the root diameter distribution at the community level. Soil parameters are also indicated. All measurements were conducted along a successional gradient on roadsides in the Mediterranean region (Montpellier, France, 43°6′N, 3°8′E). These data were used in the article entitled ""Dissecting fine root diameter distribution at the community level captures root morpological diversity"" from Erktan, A., Roumet, C., Munoz, F (in press) in Oikos (2022).",mds,True,findable,129,4,0,1,0,2022-02-02T03:29:45.000Z,2022-02-02T03:29:47.000Z,dryad.dryad,dryad,"FOS: Biological sciences,FOS: Biological sciences","[{'subject': 'FOS: Biological sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['15071 bytes'], +10.6084/m9.figshare.21285662.v1,Additional file 2 of Prognosis of lasso-like penalized Cox models with tumor profiling improves prediction over clinical data alone and benefits from bi-dimensional pre-screening,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 2. A document containing supplementary Table 1 with TCGA cancer abbreviations.,mds,True,findable,0,0,0,0,0,2022-10-06T07:36:17.000Z,2022-10-06T07:36:17.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Pharmacology,Immunology,FOS: Clinical medicine,69999 Biological Sciences not elsewhere classified,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Cancer","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",['450424 Bytes'], +10.5061/dryad.m7m72,Data from: Loss of connectivity among island-dwelling Peary caribou following sea ice decline,Dryad,2016,en,Dataset,Creative Commons Zero v1.0 Universal,"Global warming threatens to reduce population connectivity for terrestrial wildlife through significant and rapid changes to sea ice. Using genetic fingerprinting, we contrasted extant connectivity in island-dwelling Peary caribou in northern Canada with continental-migratory caribou. We next examined if sea-ice contractions in the last decades modulated population connectivity and explored the possible impact of future climate change on long-term connectivity among island caribou. We found a strong correlation between genetic and geodesic distances for both continental and Peary caribou, even after accounting for the possible effect of sea surface. Sea ice has thus been an effective corridor for Peary caribou, promoting inter-island connectivity and population mixing. Using a time series of remote sensing sea-ice data, we show that landscape resistance in the Canadian Arctic Archipelago has increased by approximately 15% since 1979 and may further increase by 20–77% by 2086 under a high-emission scenario (RCP8.5). Under the persistent increase in greenhouse gas concentrations, reduced connectivity may isolate island-dwelling caribou with potentially significant consequences for population viability.",mds,True,findable,276,26,1,1,0,2016-08-24T16:45:38.000Z,2016-08-24T16:45:39.000Z,dryad.dryad,dryad,"Canadian Arctic Archipelago,isolation by distance,Rangifer tarandus","[{'subject': 'Canadian Arctic Archipelago'}, {'subject': 'isolation by distance'}, {'subject': 'Rangifer tarandus'}]",['50097 bytes'], +10.57757/iugg23-4610,Site-specific seismic hazard assessment of sensible facilities: The importance of local seismological instrumentation,GFZ German Research Centre for Geosciences,2023,en,ConferencePaper,Creative Commons Attribution 4.0 International,"<!--!introduction!--><b></b><p>The installation of seismic instrumentation (broadband seismometers and/or accelerometers) in the immediate vicinity of a sensitive facility (e.g., nuclear site) may be considered a significant investment, but it provides important information to improve the reliability of site-specific seismic hazard studies. Beyond the use of these data to estimate the amplification between a local reference station and a station subject to site effect (classical SSR approach), the introduction of these local records in regional or national databases allows an analysis of the soil-response of these sensitive sites with respect to more global references. In the case of a generalized inversion technique (GIT), it is possible to determine the response of the sites of interest with respect to the same reference as the one used to constrain the inversion. Similarly, in the case of a ground motion models (GMM) derivation, it is possible to analyse the dS2S terms in order to estimate the response of sites of interest relative to the median of the prediction model. This work shows the results obtained using these approaches for two sensitive industrial sites with local instrumentation implemented over a period of about ten years, located in the South-East of France (low to moderate seismicity zone). We discuss the advantages and disadvantages of these approaches with respect to other methods used in site-specific seismic hazard estimation, as well as the minimum deployment duration required.</p>",fabricaForm,True,findable,0,0,0,0,0,2023-07-03T19:58:22.000Z,2023-07-04T18:43:39.000Z,gfz.iugg2023,gfz,,,, +10.57757/iugg23-4598,Towards a reduction of the high-frequency uncertainty of ground-motion-models: Inventory of insufficiently taken into account phenomena that disturb seismic record,GFZ German Research Centre for Geosciences,2023,en,ConferencePaper,Creative Commons Attribution 4.0 International,"<!--!introduction!--><b></b><p>Reducing the standard deviation of ground motion models (GMMs) is a challenge that has engaged the seismic hazard scientific community for many years with results that unfortunately do not match the dedicated efforts. The work of the last few years, allowing the processing of an ever-increasing amount of data with machine learning approaches, has allowed great progress towards the reduction of these uncertainties, nevertheless, the high frequency uncertainty remains large, especially for GMMs developed in the Fourier domain.</p>While these machine learning approaches are particularly promising, it is nevertheless necessary for the seismologist to provide them with the relevant parameters to test. In this work, we inventory a set of phenomena that disturb high frequency signals and that are not or rarely taken into account. We present a synthesis of recent results on different phenomena: small-scale soil-structure interaction generated by slabs or pillars often used to couple seismometers and accelerometers, depth effect, small-scale topography effect, seasonal variations. We discuss the interest of a better documentation of the installation conditions within the metadata associated to seismic motion databases.",fabricaForm,True,findable,0,0,0,0,0,2023-07-03T19:58:18.000Z,2023-07-07T12:36:25.000Z,gfz.iugg2023,gfz,,,, +10.6084/m9.figshare.22075664,Supplementary document for Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃ - 6292687.pdf,Optica Publishing Group,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary model information and results,mds,True,findable,0,0,0,0,0,2023-07-26T13:41:37.000Z,2023-09-01T15:03:20.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],['14116626 Bytes'], +10.6084/m9.figshare.22625608.v1,"Additional file 1 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:19.000Z,2023-04-13T18:48:19.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['1508179 Bytes'], +10.5061/dryad.qrfj6q5fk,Derivation of the functional response of a foraging herbivore,Dryad,2021,en,Dataset,Creative Commons Zero v1.0 Universal,"The actual rate of food intake of a consumer depends on the way this animal shares its time between its different activities. Using a mathematical approach, we show how the proportions of time an herbivore spends searching for food, cropping food, and handling food, determine its feeding rate. We also show how this feeding rate is affected by the animal's ability to detect food and to handle it. The equation we finally get corresponds to the herbivore's functional response.",mds,True,findable,141,8,0,1,0,2021-05-06T12:45:00.000Z,2021-05-06T12:45:01.000Z,dryad.dryad,dryad,,,['552842 bytes'], +10.5061/dryad.pf420,Data from: Onset of autumn shapes the timing of birth in Pyrenean chamois more than onset of spring,Dryad,2016,en,Dataset,Creative Commons Zero v1.0 Universal,"1. In seasonal environments, birth dates are a central component for a species’ life history, with potential long-term fitness consequences. Yet our understanding of selective pressures of environmental changes on birth dates is limited in wild mammals due to the difficulty of data collection. In a context of rapid climate change, the question of a possible mismatch between plant phenology and birth phenology also remains unanswered for most species. 2. We assessed whether and how the timing of birth in a mountain mammal (isard, Rupicapra pyrenaica) tracked changes in plant growing season, accounting for maternal traits, individual heterogeneity, and population density. We not only focused on spring conditions but also assessed to what extent onset of autumn can be a driver of phenological biological events and compared the magnitude of the response to the magnitude of the environmental changes. We relied on a 22-year study based on intensively monitored marked individuals of known age. 3. Births were highly synchronized (80% of kids born within 25 days) and highly repeatable (84%; among-females variation of 9.6 days, withinfemale variation of 4.2 days). Individual phenotypic plasticity allows females to respond rapidly to inter-annual changes in plant phenology but did not prevent the existence of a mismatch: a 10-day advance in the autumn or spring plant phenology led to 3.9 and 1.3 days advance in birth dates, respectively. 4. Our findings suggest that plant phenology may act as a cue to induce important stages of the reproductive cycle (e.g., conception and gestation length), subsequently affecting parturition dates, and stressed the importance of focusing on long-term changes during spring for which females may show much lower adaptive potential than during autumn. These results also question the extent to which individual plasticity along with high heterogeneity among individuals will allow species to cope with demographic consequences of climate changes.",mds,True,findable,216,17,1,1,0,2015-09-29T14:57:08.000Z,2015-09-29T14:57:09.000Z,dryad.dryad,dryad,"Pyrenean chamois,onsets of spring and autumn,Rupicapra pyrenaica,birth phenology,marked animals","[{'subject': 'Pyrenean chamois'}, {'subject': 'onsets of spring and autumn'}, {'subject': 'Rupicapra pyrenaica'}, {'subject': 'birth phenology'}, {'subject': 'marked animals'}]",['34973 bytes'], +10.6084/m9.figshare.22625626.v1,"Additional file 7 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 7.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:06.000Z,2023-04-13T18:48:06.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['122896 Bytes'], +10.6084/m9.figshare.22625632.v1,"Additional file 9 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 9.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:02.000Z,2023-04-13T18:48:03.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['1022601 Bytes'], +10.5281/zenodo.10048444,Spring snow albedo feedback in daily data over Russia: Comparing in-situ measurements with reanalysis products,Zenodo,2023,,Text,Creative Commons Attribution 4.0 International,"Poster for the ASSW 2017 and AGU 2016 conference showing results from Wegmann et al. 2018. + +Wegmann, M., Dutra, E., Jacobi, H.W. & Zolina, O. (2018). Spring snow albedo feedback over Northern Eurasia: Comparing in-situ measurements with reanalysis products. The Cryosphere, 12(6), 1887-1898",api,True,findable,0,0,0,0,0,2023-10-27T18:27:29.000Z,2023-10-27T18:27:29.000Z,cern.zenodo,cern,"snow,albedo,reanalysis,climate,observations,russia","[{'subject': 'snow'}, {'subject': 'albedo'}, {'subject': 'reanalysis'}, {'subject': 'climate'}, {'subject': 'observations'}, {'subject': 'russia'}]",, +10.6084/m9.figshare.21285659.v1,Additional file 1 of Prognosis of lasso-like penalized Cox models with tumor profiling improves prediction over clinical data alone and benefits from bi-dimensional pre-screening,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 1. A document containing supplementary materials.,mds,True,findable,0,0,0,0,0,2022-10-06T07:36:16.000Z,2022-10-06T07:36:16.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Pharmacology,Immunology,FOS: Clinical medicine,69999 Biological Sciences not elsewhere classified,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Cancer","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",['112261 Bytes'], +10.48649/asmn.632,Sur les traces du mémorial. Chronologie des actes d’appropriation et de dégradation du Mémorial de l’abolition de l’esclavage de Nantes,Espaces et Sociétés - UMR 6590,2021,fr,JournalArticle,Creative Commons Attribution Non Commercial Share Alike 4.0 International,"En juin 2020, plusieurs sculptures de figures coloniales et esclavagistes ont été vandalisées dans différentes villes. Ce phénomène n’est pas récent. Depuis des siècles, des artefacts mémoriels sont édifiés, encensés, ravagés. Ces dégradations rappellent que les mémoires de l’esclavage restent conflictuelles et montrent que la simple présence d’édifices dans l’espace public soulève des questions de l’ordre du symbole, de la représentation et de la commémoration. Le Mémorial de l’abolition de l’esclavage nantais n’échappe pas à ces contestations.",fabricaForm,True,findable,0,0,0,0,0,2021-10-01T08:29:08.000Z,2021-10-01T09:19:04.000Z,jbru.eso,jbru,"esclavage,association,mémoire,migrants,dégradation","[{'subject': 'esclavage', 'valueUri': 'http://skos.um.es/unescothes/C03660', 'schemeUri': 'http://skos.um.es/unescothes', 'subjectScheme': 'skos', 'classificationCode': 'C03660'}, {'subject': 'association', 'valueUri': 'http://skos.um.es/unescothes/C00279', 'schemeUri': 'http://skos.um.es/unescothes', 'subjectScheme': 'skos', 'classificationCode': 'C00279'}, {'subject': 'mémoire', 'valueUri': 'http://skos.um.es/unescothes/C00656', 'schemeUri': 'http://skos.um.es/unescothes', 'subjectScheme': 'skos', 'classificationCode': 'C00656'}, {'subject': 'migrants'}, {'subject': 'dégradation'}]",, +10.6084/m9.figshare.c.6272697.v1,Synchronization of small-scale seismic clusters reveals large-scale plate deformation,figshare,2022,,Collection,Creative Commons Attribution 4.0 International,"Abstract It has long been observed that periods of intense seismic activity in a region alternate with periods of relative quiescence, but establishing whether or not this intermittency is driven by broad-scale physical processes occurring in the Earth, remains a challenge. Here, we address this question of long-range triggering by a large-scale analysis of evolution of the seismicity between 2003 and 2017 in the Anatolia region. Two multi-year periods of synchronous high seismicity rate in 27 seismicity clusters across the Anatolian plate are evidenced before a relatively uniform quiescence period. We argue that two remote tectonic processes are important for the timing of these activities: the 2004 M9.2 Sumatra earthquake and the 2008–2011 episode of slab rollback/deformation in the Hellenic subduction, even if a clear causal mechanism is still lacking. Graphical Abstract",mds,True,findable,0,0,0,0,0,2022-10-30T04:22:22.000Z,2022-10-30T04:22:23.000Z,figshare.ars,otjm,"Geology,FOS: Earth and related environmental sciences","[{'subject': 'Geology'}, {'subject': 'FOS: Earth and related environmental sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.5061/dryad.dc25730,Data from: Unlocking biodiversity and conservation studies in highâ€diversity environments using environmental DNA (eDNA): a test with Guianese freshwater fishes,Dryad,2018,en,Dataset,Creative Commons Zero v1.0 Universal,"Determining the species compositions of local assemblages is a prerequisite to understanding how anthropogenic disturbances affect biodiversity. However, biodiversity measurements often remain incomplete due to the limited efficiency of sampling methods. This is particularly true in freshwater tropical environments that host rich fish assemblages, for which assessments are uncertain and often rely on destructive methods. Developing an efficient and non-destructive method to assess biodiversity in tropical freshwaters is highly important. In this study, we tested the efficiency of environmental DNA (eDNA) metabarcoding to assess the fish diversity of 39 Guianese sites. We compared the diversity and composition of assemblages obtained using traditional and metabarcoding methods. More than 7,000 individual fish belonging to 203 Guianese fish species were collected by traditional sampling methods, and ~17 million reads were produced by metabarcoding, among which ~8 million reads were assigned to 148 fish taxonomic units, including 132 fish species. The two methods detected a similar number of species at each site, but the species identities partially matched. The assemblage compositions from the different drainage basins were better discriminated using metabarcoding, revealing that while traditional methods provide a more complete but spatially limited inventory of fish assemblages, metabarcoding provides a more partial but spatially extensive inventory. eDNA metabarcoding can therefore be used for rapid and large-scale biodiversity assessments, while at a local scale, the two approaches are complementary and enable an understanding of realistic fish biodiversity.",mds,True,findable,361,72,1,1,0,2018-05-09T18:32:17.000Z,2018-05-09T18:32:18.000Z,dryad.dryad,dryad,"fish assemblage,reference database,Teleostei","[{'subject': 'fish assemblage'}, {'subject': 'reference database'}, {'subject': 'Teleostei'}]",['5186813450 bytes'], +10.6084/m9.figshare.22807641.v1,Additional file 2 of Phenotype and imaging features associated with APP duplications,figshare,2023,,Image,Creative Commons Attribution 4.0 International,Additional file 2: Supp Figure 2. MRI scans of three patients from the BES_262 family showing the large heterogeneity of cerebral imaging. A: MRI of 262-001; B: MRI of 262-003; C: MRI of 262-004.,mds,True,findable,0,0,0,0,0,2023-05-12T03:40:50.000Z,2023-05-12T03:40:51.000Z,figshare.ars,otjm,"Biochemistry,Medicine,Cell Biology,Neuroscience,Science Policy","[{'subject': 'Biochemistry'}, {'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Neuroscience'}, {'subject': 'Science Policy'}]",['779176 Bytes'], +10.5061/dryad.4mj8gg0,"Data from: Genetic, morphological and ecological variation across a sharp hybrid zone between two alpine butterflies species",Dryad,2019,en,Dataset,Creative Commons Zero v1.0 Universal,"Identifying the mechanisms involved in the formation and maintenance of species is a central question in evolutionary biology and distinguishing the selective drivers of populations’ divergence from demographic processes is of particular interest to better understand the speciation process. Hybrid zones are recognized to provide ideal places to investigate the genetic architecture of speciation and to identify the mechanisms allowing diverging species to maintain their integrity in the face of gene flow. Here, we studied two alpine butterfly species in the genus Coenonympha: C. macromma and C. gardetta, which can be found flying together and hybridizing in narrow contact zones in the southern French Alps. We characterised the genomic composition of individuals, their morphology and their local habitat requirements, within and around a hybrid zone. Cline analysis showed that a significant portion of the genomic regions analysed were impermeable to introgression across a sharp hybrid zone (9 km wide), despite ongoing hybridisation between the species. We also found concordance between genetic, morphological and environmental variation across the hybrid zone, suggesting a coupling of different reproductive barriers. Habitat characteristics such as the presence of trees and shrubs and the start of the growing season were strongly associated with the genetic variation and we found evidence of genetic divergence at genetic markers associated with morphology and physiology, putatively involved in visual or environmental reproductive isolation. We discuss the various behavioural and ecological factors that might interplay to maintain current levels of divergence and gene flow between this species pair.",mds,True,findable,146,11,0,0,0,2020-01-17T17:43:48.000Z,2020-01-17T17:43:49.000Z,dryad.dryad,dryad,"genetic cline,Coenonympha,Alps,allopatric/geographic speciation","[{'subject': 'genetic cline'}, {'subject': 'Coenonympha'}, {'subject': 'Alps'}, {'subject': 'allopatric/geographic speciation'}]",['220159829 bytes'], +10.6084/m9.figshare.24483508.v1,Additional file 1 of Cefoxitin versus carbapenems as definitive treatment for extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteremia in intensive care unit: a propensity-matched retrospective analysis,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1. Table S1: Analysis of risk factors for 30-day clinical failure in patients with ESBL-KP bacteremia. Table S2: Matching graph of the propensity score.,mds,True,findable,0,0,0,0,0,2023-11-02T05:00:05.000Z,2023-11-02T05:00:06.000Z,figshare.ars,otjm,"Space Science,Medicine,Microbiology,FOS: Biological sciences,Cancer,Infectious Diseases,FOS: Health sciences","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Microbiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['61375 Bytes'], +10.6084/m9.figshare.22620043,"Additional file 5 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 5: Quantitative PCR results comparing relative expression of NOS3 mRNA in cells transfected with the wild type and with the M035 mutated cDNA.,mds,True,findable,0,0,0,0,0,2023-04-13T14:39:35.000Z,2023-04-13T14:44:39.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['14233 Bytes'], +10.6084/m9.figshare.c.6606032,ICU admission for solid cancer patients treated with immune checkpoint inhibitors,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Immune checkpoint inhibitors (ICI) have revolutionized the management of cancer. They can induce immune-related adverse events (irAE) leading to intensive care unit (ICU) admission. We aimed to describe irAEs for ICU admissions in solid cancer patients treated with ICIs. Methods This prospective multicenter study was conducted in France and Belgium. Adult patients with solid tumor and treated with systemic ICIs within the last 6 months, requiring non-programmed ICU admission were included. Patients admitted for microbiologically documented sepsis were excluded. Imputability of irAEs in ICU admissions was described according to the WHO-UMC classification system at ICU admission and at ICU discharge. The use of immunosuppressant treatment was reported. Results 115 patients were eligible. Solid tumor was mainly lung cancer (n = 76, 66%) and melanoma (n = 18, 16%). They were mainly treated with an anti-PD-(L)1 alone (n = 110, 96%). Main ICU admission reasons were acute respiratory failure (n = 66, 57%), colitis (n = 14, 13%), and cardiovascular disease (n = 13, 11%). ICU admission was considered “likely†associated with irAE for 48% (n = 55) of patients. Factors independently associated with irAE were a good ECOG performance status (PS) (ECOG-PS of 0 or 1 vs. ECOG-PS of 2–3, odds ratio [OR] = 6.34, 95% confidence interval [95% CI] 2.13–18.90, and OR = 3.66, 95% CI 1.33–10.03, respectively), and a history of irAE (OR = 3.28, 95% CI 1.19–9.01). Steroids were prescribed for 41/55 (75%) patients with ICU admission “likely†related to irAE. Three patients were subsequently treated with immunosuppressants. Conclusion IrAEs accounted for half of ICU admissions in cancer patients receiving ICIs. They could be treated with steroids. Identifying the imputability of irAEs in ICU admissions remains a challenge.",mds,True,findable,0,0,0,0,0,2023-04-19T03:54:42.000Z,2023-04-19T03:54:43.000Z,figshare.ars,otjm,"Medicine,Pharmacology,Biotechnology,39999 Chemical Sciences not elsewhere classified,FOS: Chemical sciences,Immunology,FOS: Clinical medicine,Cancer","[{'subject': 'Medicine'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': '39999 Chemical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Chemical sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",, +10.6084/m9.figshare.22735399.v1,"Additional file 1 of Multiple trauma in pregnant women: injury assessment, fetal radiation exposure and mortality. A multicentre observational study",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary Material 1,mds,True,findable,0,0,0,0,0,2023-05-03T03:19:15.000Z,2023-05-03T03:19:15.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Biotechnology,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Developmental Biology,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Biotechnology'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Developmental Biology'}, {'subject': 'Science Policy'}]",['675112 Bytes'], +10.6084/m9.figshare.22735402,"Additional file 2 of Multiple trauma in pregnant women: injury assessment, fetal radiation exposure and mortality. A multicentre observational study",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary Material 2,mds,True,findable,0,0,0,0,0,2023-05-03T03:19:16.000Z,2023-05-03T03:19:17.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Biotechnology,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Developmental Biology,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Biotechnology'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Developmental Biology'}, {'subject': 'Science Policy'}]",['22640 Bytes'], +10.6084/m9.figshare.21351214.v1,Additional file 1 of Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Fig. S1. Study flowchart. Table S1. Baseline characteristics and mortality in the groups with vs. without mild-to-moderate postresuscitation shock (PRS) at intensive-care-unit (ICU) admission. Table S2. Multivariate logistic regression modelling to identify admission variables associated with a favourable outcome on day 90 in the overall population (n = 532).,mds,True,findable,0,0,0,0,0,2022-10-18T03:24:06.000Z,2022-10-18T03:24:07.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Physiology,FOS: Biological sciences,Pharmacology,Biotechnology,Cancer,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Physiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}]",['78458 Bytes'], +10.5281/zenodo.10000776,Metallic nickel pillar X-ray spectral ptychographic dataset,Zenodo,2023,,Dataset,Creative Commons Attribution 4.0 International,"This dataset was acquired at the SWING beamline at the French synchrotron SOLEIL. The dataset was obtained by conducting spectral 2D X-ray ptychography on a 7-micron diameter metallic nickel pillar. An energy scan was performed from 8.3 KeV to 8.4 KeV with a 1 eV step, including the resonant energy of nickel at 8.333 KeV. For each energy acquisition, the ptychographic scanning parameters consisted of 242 diffraction patterns from a field of view of 14x12 mm², with an exposure time of 100 ms per point. The ptychographic reconstruction was carried out using the PtychoShelves Matlab software package, involving 200 iterations of the difference map (DM) algorithm, followed by 100 iterations of the maximum likelihood (ML) algorithm.",api,True,findable,0,0,0,0,0,2023-10-13T14:05:21.000Z,2023-10-13T14:05:21.000Z,cern.zenodo,cern,,,, +10.25384/sage.c.6377642.v1,Validation of a screening algorithm for hepatic fibrosis by Doppler ultrasound and elastography in a general population,SAGE Journals,2023,,Collection,Creative Commons Attribution 4.0 International,"BackgroundEarly detection can prevent the initial stages of fibrosis from progressing to cirrhosis.PurposeTo evaluate an algorithm combining three echographic indicators and elastographic measurements to screen for hepatic fibrosis in an unselected population.Material and MethodsFrom May 2017 to June 2018, all patients with no history and no known chronic liver disease who were referred for an ultrasound (US) were prospectively included in eight hospitals. The indicators being sought were liver surface irregularity, demodulation of hepatic veins, and spleen length >110 mm. Patients presenting at least one of these underwent elastography measurements with virtual touch quantification (VTQ) or supersonic shear imaging (SSI). If elastography was positive, patients were referred to hepatologist for fibrosis evaluation. Reference standard was obtained by FibroMeter<sup>VCTE</sup> or biopsy. A FibroMeter<sup>VCTE</sup> result >0.384 indicated a “necessary referral†to a hepatologist.ResultsOf the 1501 patients included, 504 (33.6%) were positive for at least one US indicator. All of them underwent US elastography, with 85 being positive. Of the patients, 58 (3.6%) had a consultation with a liver specialist: 21 had positive FibroMeter<sup>VCTE</sup> and nine had an indication of biopsy for suspicion of fibrosis. This screening algorithm made it possible to diagnose 1.6% of patients in our population with unknown fibrosis. Of the patients, 50% referred to the liver specialist were “necessary referrals.â€ConclusionOur study suggests that three simple US indicators with no systematic elastographic measurement could be applied in day-to-day practice to look for hepatic fibrosis in an unsuspected population allowing relevant referrals to a hepatologist.",mds,True,findable,0,0,0,0,0,2023-01-10T01:14:28.000Z,2023-01-10T01:14:28.000Z,figshare.sage,sage,"110320 Radiology and Organ Imaging,FOS: Clinical medicine","[{'subject': '110320 Radiology and Organ Imaging', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.20080019.v4,Views Evolution 5 Minutes Frequency,figshare,2022,,Dataset,Creative Commons Attribution 4.0 International,"This dataset contains 1012 videos posted between February 2, 2022 and February 16, 2022. For every video it records the amount of views every 5 minutes.",mds,True,findable,0,0,0,0,0,2022-11-24T11:47:40.000Z,2022-11-24T11:47:41.000Z,figshare.ars,otjm,"Applications in physical sciences,Complex physical systems","[{'subject': 'Applications in physical sciences'}, {'subject': 'Complex physical systems'}]",['552808145 Bytes'], +10.6084/m9.figshare.22599661,Additional file 1 of Procalcitonin to reduce exposure to antibiotics and individualise treatment in hospitalised old patients with pneumonia: a randomised study,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1.,mds,True,findable,0,0,0,0,0,2023-04-13T09:42:54.000Z,2023-04-13T09:42:55.000Z,figshare.ars,otjm,"Space Science,Medicine,Immunology,FOS: Clinical medicine,Cancer,111714 Mental Health,FOS: Health sciences,110309 Infectious Diseases","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '110309 Infectious Diseases', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}]",['317731 Bytes'], +10.6084/m9.figshare.c.6804540.v1,Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Pneumocystis jirovecii pneumonia (PJP) is an opportunistic, life-threatening disease commonly affecting immunocompromised patients. The distribution of predisposing diseases or conditions in critically ill patients admitted to intensive care unit (ICU) and subjected to diagnostic work-up for PJP has seldom been explored. Materials and methods The primary objective of the study was to describe the characteristics of ICU patients subjected to diagnostic workup for PJP. The secondary objectives were: (i) to assess demographic and clinical variables associated with PJP; (ii) to assess the performance of Pneumocystis PCR on respiratory specimens and serum BDG for the diagnosis of PJP; (iii) to describe 30-day and 90-day mortality in the study population. Results Overall, 600 patients were included in the study, of whom 115 had presumptive/proven PJP (19.2%). Only 8.8% of ICU patients subjected to diagnostic workup for PJP had HIV infection, whereas hematological malignancy, solid tumor, inflammatory diseases, and solid organ transplants were present in 23.2%, 16.2%, 15.5%, and 10.0% of tested patients, respectively. In multivariable analysis, AIDS (odds ratio [OR] 3.31; 95% confidence interval [CI] 1.13–9.64, p = 0.029), non-Hodgkin lymphoma (OR 3.71; 95% CI 1.23–11.18, p = 0.020), vasculitis (OR 5.95; 95% CI 1.07–33.22, p = 0.042), metastatic solid tumor (OR 4.31; 95% CI 1.76–10.53, p = 0.001), and bilateral ground glass on CT scan (OR 2.19; 95% CI 1.01–4.78, p = 0.048) were associated with PJP, whereas an inverse association was observed for increasing lymphocyte cell count (OR 0.64; 95% CI 0.42–1.00, p = 0.049). For the diagnosis of PJP, higher positive predictive value (PPV) was observed when both respiratory Pneumocystis PCR and serum BDG were positive compared to individual assay positivity (72% for the combination vs. 63% for PCR and 39% for BDG). Cumulative 30-day mortality and 90-day mortality in patients with presumptive/proven PJP were 52% and 67%, respectively. Conclusion PJP in critically ill patients admitted to ICU is nowadays most encountered in non-HIV patients. Serum BDG when used in combination with respiratory Pneumocystis PCR could help improve the certainty of PJP diagnosis.",mds,True,findable,0,0,0,0,0,2023-08-25T03:21:17.000Z,2023-08-25T03:21:17.000Z,figshare.ars,otjm,"Medicine,Biotechnology,Immunology,FOS: Clinical medicine,Biological Sciences not elsewhere classified,Cancer,Science Policy,Mental Health,Infectious Diseases,FOS: Health sciences,Virology","[{'subject': 'Medicine'}, {'subject': 'Biotechnology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}, {'subject': 'Mental Health'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Virology'}]",, +10.6084/m9.figshare.22625611.v1,"Additional file 2 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 2.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:18.000Z,2023-04-13T18:48:18.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['374370 Bytes'], +10.6084/m9.figshare.22807638.v1,Additional file 1 of Phenotype and imaging features associated with APP duplications,figshare,2023,,Image,Creative Commons Attribution 4.0 International,Additional file 1: Supp Figure 1. MRI scans of two APP duplication carriers showing deep microbleeds (orange arrows). A: EXT_814 carrying a 5.7Mb duplication and B: EXT_1516 carrying a 0.95Mb duplication.,mds,True,findable,0,0,0,0,0,2023-05-12T03:40:49.000Z,2023-05-12T03:40:49.000Z,figshare.ars,otjm,"Biochemistry,Medicine,Cell Biology,Neuroscience,Science Policy","[{'subject': 'Biochemistry'}, {'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Neuroscience'}, {'subject': 'Science Policy'}]",['568868 Bytes'], +10.6084/m9.figshare.c.6590285,"Individual and environmental determinants associated with longer times to access pediatric rheumatology centers for patients with juvenile idiopathic arthritis, a JIR cohort study",figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Despite guidelines, poor access to appropriate care for juvenile idiopathic arthritis (JIA) patients remains a global issue. Prompt referral to a pediatric rheumatology (PR) center and effective care is known to be critical for changing the natural history of the disease and improving long-term prognosis. This project assesses socio-economic factors of delayed referral to a pediatric rheumatologist (PRst) for JIA patients in France and Switzerland within the Juvenile Inflammatory Rheumatism (JIR) Cohort. Methods All patients diagnosed with JIA, presenting at one center of the JIRcohort in France or Switzerland with additional data on referral pathway were included. Patient characteristics at first visit to the PR center, dates of visits to healthcare providers during referral, and parent characteristics were extracted from the JIRcohort database. Results Two hundred fifty children were included. The overall median time to first PR assessment was 2.4 months [1.3; 6.9] and ranged widely across the JIA subtypes, from 1.4 months [0.6; 3.8] for children with systemic juvenile idiopathic arthritis (sJIA) to 5.3 months [2.0; 19.1] for children with enthesitis-related arthritis (ERA). A diagnosis of ERA and an appointment with an orthopedist during the referral pathway were significantly associated with a longer time before the first PR visit (hazard ratio HR 0.50 [95% CI: 0.29; 0.84]) and HR 0.68 [95% CI: 0.49; 0.93], respectively) in multivariable analysis. Having a mother with a post-graduate educational attainment level was tendentially associated with a shorter time before the first PR visit, (HR 1.32 [95% CI: 0.99; 1.78]). Conclusions Time to first PRst visit was most often short compared to other studies and close to the British recommendations. However, this time remained too long for many patients. We observed no social inequities in access to a PRst, but we show the need to improve effective pathway and access to a PR center for JIA patients.",mds,True,findable,0,0,0,0,0,2023-04-13T13:55:20.000Z,2023-04-13T13:55:20.000Z,figshare.ars,otjm,"Medicine,Biotechnology,Ecology,FOS: Biological sciences,Immunology,FOS: Clinical medicine,Cancer,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Biotechnology'}, {'subject': 'Ecology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}]",, +10.6084/m9.figshare.c.6650322,Digital undergraduate medical education and patient and carer involvement: a rapid systematic review of current practice,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Involving patients and carers in medical students’ learning aims to centralise the perspective of healthcare users and supports our future medical workforce in the development of key skills. Medical schools are increasingly using digital technology for teaching and it is timely to understand how to maintain patient and carer involvement in this context. Methods Ovid MEDLINE, Ovid EMBASE and medRxiv were searched in October 2020 and reference lists of key articles were hand searched. Eligible studies reported authentic patient or carer involvement in undergraduate medical education where technology was also used. Study quality was assessed by the Mixed Methods Appraisal Tool (MMAT). Levels of patient or carer involvement were assessed using Towle et al.’s (2010) taxonomy, from Level 1 (lowest level) to Level 6 (highest level). Results Twenty studies were included in this systematic review. In 70% of studies, patients and carers featured in video or web-based case scenarios with no interaction between healthcare users and students. The remaining 30% of studies reported real-time interactions between students and patients via remote clinical encounters. Digital teaching sessions involving patients or carers were perceived to be valuable by students and educators, and increased student engagement, patient-centred attitudes, clinical knowledge, and communication skills. No studies reported the perspective of patients or carers. Discussion Digital technology has not yet driven higher levels of patient and carer involvement in medical training. “Live†interactions between students and patients are becoming more common but challenges need addressing to ensure positive experiences for all involved. Future teaching should enhance the role of patients and carers in medical education and support them to overcome any potential barriers to doing so remotely.",mds,True,findable,0,0,0,0,0,2023-05-17T03:24:27.000Z,2023-05-17T03:24:27.000Z,figshare.ars,otjm,"Medicine,Science Policy,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,111714 Mental Health,FOS: Health sciences","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.22617740.v1,"Additional file 1 of Individual and environmental determinants associated with longer times to access pediatric rheumatology centers for patients with juvenile idiopathic arthritis, a JIR cohort study",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1. Location of the 20 pediatric rheumatology centers (using Google Maps).,mds,True,findable,0,0,0,0,0,2023-04-13T15:53:31.000Z,2023-04-13T15:53:32.000Z,figshare.ars,otjm,"Medicine,Biotechnology,Ecology,FOS: Biological sciences,Immunology,FOS: Clinical medicine,Cancer,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Biotechnology'}, {'subject': 'Ecology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}]",['99200 Bytes'], +10.25384/sage.c.6377642,Validation of a screening algorithm for hepatic fibrosis by Doppler ultrasound and elastography in a general population,SAGE Journals,2023,,Collection,Creative Commons Attribution 4.0 International,"BackgroundEarly detection can prevent the initial stages of fibrosis from progressing to cirrhosis.PurposeTo evaluate an algorithm combining three echographic indicators and elastographic measurements to screen for hepatic fibrosis in an unselected population.Material and MethodsFrom May 2017 to June 2018, all patients with no history and no known chronic liver disease who were referred for an ultrasound (US) were prospectively included in eight hospitals. The indicators being sought were liver surface irregularity, demodulation of hepatic veins, and spleen length >110 mm. Patients presenting at least one of these underwent elastography measurements with virtual touch quantification (VTQ) or supersonic shear imaging (SSI). If elastography was positive, patients were referred to hepatologist for fibrosis evaluation. Reference standard was obtained by FibroMeter<sup>VCTE</sup> or biopsy. A FibroMeter<sup>VCTE</sup> result >0.384 indicated a “necessary referral†to a hepatologist.ResultsOf the 1501 patients included, 504 (33.6%) were positive for at least one US indicator. All of them underwent US elastography, with 85 being positive. Of the patients, 58 (3.6%) had a consultation with a liver specialist: 21 had positive FibroMeter<sup>VCTE</sup> and nine had an indication of biopsy for suspicion of fibrosis. This screening algorithm made it possible to diagnose 1.6% of patients in our population with unknown fibrosis. Of the patients, 50% referred to the liver specialist were “necessary referrals.â€ConclusionOur study suggests that three simple US indicators with no systematic elastographic measurement could be applied in day-to-day practice to look for hepatic fibrosis in an unsuspected population allowing relevant referrals to a hepatologist.",mds,True,findable,0,0,0,0,0,2023-01-10T01:14:28.000Z,2023-01-10T01:14:28.000Z,figshare.sage,sage,"110320 Radiology and Organ Imaging,FOS: Clinical medicine","[{'subject': '110320 Radiology and Organ Imaging', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.21432228,Additional file 1 of Synchronization of small-scale seismic clusters reveals large-scale plate deformation,figshare,2022,,Text,Creative Commons Attribution 4.0 International,"Additional file 1: Text S1. Normalized cumulative distributions of the magnitude and 9 magnitude completeness of each seismic cluster. Text S2. Cumulative Seismicity. Text S3. Seismicity Rates. Text S4. Singular Value Decomposition. Figure S1. Normalized cumulative distributions of the magnitude of earthquakes 75 for each cluster using the same color coding as in Fig.2. Magnitude completeness 76 of the clusters for 4 different time windows a) 2003 – 2008 (Mc=2.9) b) 2003 – 77 2017 (Mc=2.7) c) 2004 – 2006 (Mc=2.9) d) 2007-2017 (Mc=2.7). Figure S2. Gaussian smoothing function. Figure S3. Processing steps for the seismicity time series. (a) Cumulative 88 number of earthquakes (blue) and daily seismic activity (red) for the Simav 89 cluster (b) after declustering. All plots are normalized by their maximum values. 90 The daily seismic activity is smoothed using the Gaussian function of Figure S2. Figure S4. Singular values of the matrix constructed from daily seismicity time series of the clusters. They are normalized by the first singular value. Figure S5-1. Top: Cumulative seismicity time series of 27 clusters. Bottom: Reconstructed daily seismicity rates using only the first singular value. Figure S5-2. Top: Cumulative seismicity time series of 27 clusters. Bottom: Reconstructed daily seismicity rates using only 3 largest singular values. Figure S6. Top : a) Cumulative seismicity time series of 27 clusters. Bottom: b) Reconstructed time series after removing largest 12 singular values. Figure S7. Comparison of the cumulative seismicity of 27 clusters and the seismicity rates from 2006 to 2017 using a) Kandilli Observatory and earthquake Research Institute (KOERI) ( https://koeri.boun.edu.tr/ ) b) Disaster and Emergency Management Authority of Turkey (AFAD) ( https://deprem.afad.gov.tr/ ) and c) International Seismological Center (ISC) ( http://www.isc.ac.uk/ ) catalogs. Figure S8. Top: The locations of the seismic stations of which the continuous recordings are displayed in the following figures. Middle: 24 hour recordings of NS components of 5 seismic stations (red) and filtered with 1-9Hz bandpass filter (blue). Notice the occurrence of several moderate seismic events at the selected stations in addition to smaller events. Bottom: 6 days long NS component recording of DALT station (red) and filtered with 1-9Hz bandpass filter (blue). Beneath is the spectrogram of the seismic trace. The traces are normalized by maximum values and saturated for small-magnitude events. The seismic activity is not confined to the passage of seismic waves due to Sumatra earthquake. Figure S9. Cumulative number of events of selected clusters in central and eastern Anatolia for the time period of 2004 Sumatra Mw9.2 earthquake (see Figure 1 for the locations of the clusters). Figure S10. Cumulative number of events of selected clusters in the western Anatolia for time period of Hellenic subduction earthquakes (see Figure 1 for the locations of the western clusters). Figure S11. The diagram shows cumulative seismicity of 27 clusters (a) and the seismicity rate color coded for all clusters as in Figure 2 but from 1998 to 2017 (b). The occurrence times of giant earthquakes worldwide and of large regional earthquakes are shown. The color scale is shown on the lower right corner. Figure S12. Cumulative number of earthquakes in Anatolia between 36.80N-41.00N latitudes and 25.5E-44.0E longitudes (includes all clusters in Figure 1) for varying lower magnitude cut-offs between 2.8 (‘ml28’ blue curve) and 5.8 (‘ml58’ red curve). The displayed time period is starting 4 years after the 1999 Izmit earthquake and ending with the occurrence of 2011 Van earthquake. The red curve (5.8 magnitude threshold) is showing a sharp increase during the 2004 episode and a plateau during the 2008 episode. On the contrary, the blue curve (2.8 magnitude threshold) exhibits a similar increase between both periods. Figure S13. Broadband N-S component recordings of 2004 Sumatra earthquake at seismic stations shown on top of the traces. The traces are normalized by maximum values (see the map in Figure A8 for station locations.). The period of large amplitude S wave exceeds 100sec. Figure S14. Evolution of the cumulative number of events of the clusters in the two easternmost clusters of Anatolia (see Figure 1 for the locations of the clusters).",mds,True,findable,0,0,0,0,0,2022-10-30T04:22:21.000Z,2022-10-30T04:22:22.000Z,figshare.ars,otjm,"Geology,FOS: Earth and related environmental sciences","[{'subject': 'Geology'}, {'subject': 'FOS: Earth and related environmental sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['5315032 Bytes'], +10.6084/m9.figshare.22877643,Additional file 1 of Digital undergraduate medical education and patient and carer involvement: a rapid systematic review of current practice,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1. Sample Search Strategy (Ovid MEDLINE).,mds,True,findable,0,0,0,0,0,2023-05-17T03:24:26.000Z,2023-05-17T03:24:27.000Z,figshare.ars,otjm,"Medicine,Science Policy,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,111714 Mental Health,FOS: Health sciences","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['14508 Bytes'], +10.6084/m9.figshare.23551874.v1,A systematic review of pharmacotherapy for attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders,Taylor & Francis,2023,,Text,Creative Commons Attribution 4.0 International,"The data suggests that in children and adolescents, bipolar disorder (BD) and attention deficit hyperactivity disorder (ADHD) may be strongly correlated. Even though drugs for ADHD and BD are largely accepted, there is relatively little research on the management of comorbidity in children and adolescents, particularly in terms of safety. We provide a synthesis of these findings because one hasn’t been made yet. As a primary outcome, we wanted to determine whether stimulant or non-stimulant treatment of children and adolescents with ADHD and comorbid BD was effective. As a secondary outcome, we wanted to determine tolerability, especially the risk of mood switch. The findings of this systematic review suggest that methylphenidate, when used with a mood stabilizer, may be safe and not significantly increase the risk of a manic switch or psychotic symptoms when used to treat ADHD that co-occurs with a BD. In situations where stimulants are ineffective or have low tolerance, atomoxetine also seems to be a good alternative, and also in cases of co-morbid anxiety, oppositional defiant disorder, conduct disorders, ICT disorders, and substance use disorders. Additional research with a higher level of evidence is necessary to corroborate these preliminary findings.",mds,True,findable,0,0,0,0,0,2023-06-21T07:40:07.000Z,2023-06-21T07:40:08.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Neuroscience,Physiology,FOS: Biological sciences,Pharmacology,Biotechnology,Science Policy,Mental Health","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Neuroscience'}, {'subject': 'Physiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': 'Science Policy'}, {'subject': 'Mental Health'}]",['27108 Bytes'], +10.25384/sage.21845348,sj-doc-1-acr-10.1177_02841851221138519 - Supplemental material for Validation of a screening algorithm for hepatic fibrosis by Doppler ultrasound and elastography in a general population,SAGE Journals,2023,,Text,In Copyright,"Supplemental material, sj-doc-1-acr-10.1177_02841851221138519 for Validation of a screening algorithm for hepatic fibrosis by Doppler ultrasound and elastography in a general population by Anne-Sophie Renard, Anita Paisant, Victoire Cartier, Paul Calès, Mirela Goyet-Prelipcean, Edmond Geagea, Jean-Pierre Tasu, Christine Silvain, Mathilde Wagner, Aline Le Cleach, Valérie Vilgrain, Laurent Castera, Ivan Bricault, Thomas Decaens, Céline Savoye-Collet, Hélène Montialoux, Jean-Michel Correas, Anaïs Vallet-Pichard, Jérôme Boursier and Christophe Aubé in Acta Radiologica",mds,True,findable,0,0,0,0,0,2023-01-10T01:14:28.000Z,2023-01-10T01:14:28.000Z,figshare.sage,sage,"110320 Radiology and Organ Imaging,FOS: Clinical medicine","[{'subject': '110320 Radiology and Organ Imaging', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['36864 Bytes'], +10.6084/m9.figshare.21432228.v1,Additional file 1 of Synchronization of small-scale seismic clusters reveals large-scale plate deformation,figshare,2022,,Text,Creative Commons Attribution 4.0 International,"Additional file 1: Text S1. Normalized cumulative distributions of the magnitude and 9 magnitude completeness of each seismic cluster. Text S2. Cumulative Seismicity. Text S3. Seismicity Rates. Text S4. Singular Value Decomposition. Figure S1. Normalized cumulative distributions of the magnitude of earthquakes 75 for each cluster using the same color coding as in Fig.2. Magnitude completeness 76 of the clusters for 4 different time windows a) 2003 – 2008 (Mc=2.9) b) 2003 – 77 2017 (Mc=2.7) c) 2004 – 2006 (Mc=2.9) d) 2007-2017 (Mc=2.7). Figure S2. Gaussian smoothing function. Figure S3. Processing steps for the seismicity time series. (a) Cumulative 88 number of earthquakes (blue) and daily seismic activity (red) for the Simav 89 cluster (b) after declustering. All plots are normalized by their maximum values. 90 The daily seismic activity is smoothed using the Gaussian function of Figure S2. Figure S4. Singular values of the matrix constructed from daily seismicity time series of the clusters. They are normalized by the first singular value. Figure S5-1. Top: Cumulative seismicity time series of 27 clusters. Bottom: Reconstructed daily seismicity rates using only the first singular value. Figure S5-2. Top: Cumulative seismicity time series of 27 clusters. Bottom: Reconstructed daily seismicity rates using only 3 largest singular values. Figure S6. Top : a) Cumulative seismicity time series of 27 clusters. Bottom: b) Reconstructed time series after removing largest 12 singular values. Figure S7. Comparison of the cumulative seismicity of 27 clusters and the seismicity rates from 2006 to 2017 using a) Kandilli Observatory and earthquake Research Institute (KOERI) ( https://koeri.boun.edu.tr/ ) b) Disaster and Emergency Management Authority of Turkey (AFAD) ( https://deprem.afad.gov.tr/ ) and c) International Seismological Center (ISC) ( http://www.isc.ac.uk/ ) catalogs. Figure S8. Top: The locations of the seismic stations of which the continuous recordings are displayed in the following figures. Middle: 24 hour recordings of NS components of 5 seismic stations (red) and filtered with 1-9Hz bandpass filter (blue). Notice the occurrence of several moderate seismic events at the selected stations in addition to smaller events. Bottom: 6 days long NS component recording of DALT station (red) and filtered with 1-9Hz bandpass filter (blue). Beneath is the spectrogram of the seismic trace. The traces are normalized by maximum values and saturated for small-magnitude events. The seismic activity is not confined to the passage of seismic waves due to Sumatra earthquake. Figure S9. Cumulative number of events of selected clusters in central and eastern Anatolia for the time period of 2004 Sumatra Mw9.2 earthquake (see Figure 1 for the locations of the clusters). Figure S10. Cumulative number of events of selected clusters in the western Anatolia for time period of Hellenic subduction earthquakes (see Figure 1 for the locations of the western clusters). Figure S11. The diagram shows cumulative seismicity of 27 clusters (a) and the seismicity rate color coded for all clusters as in Figure 2 but from 1998 to 2017 (b). The occurrence times of giant earthquakes worldwide and of large regional earthquakes are shown. The color scale is shown on the lower right corner. Figure S12. Cumulative number of earthquakes in Anatolia between 36.80N-41.00N latitudes and 25.5E-44.0E longitudes (includes all clusters in Figure 1) for varying lower magnitude cut-offs between 2.8 (‘ml28’ blue curve) and 5.8 (‘ml58’ red curve). The displayed time period is starting 4 years after the 1999 Izmit earthquake and ending with the occurrence of 2011 Van earthquake. The red curve (5.8 magnitude threshold) is showing a sharp increase during the 2004 episode and a plateau during the 2008 episode. On the contrary, the blue curve (2.8 magnitude threshold) exhibits a similar increase between both periods. Figure S13. Broadband N-S component recordings of 2004 Sumatra earthquake at seismic stations shown on top of the traces. The traces are normalized by maximum values (see the map in Figure A8 for station locations.). The period of large amplitude S wave exceeds 100sec. Figure S14. Evolution of the cumulative number of events of the clusters in the two easternmost clusters of Anatolia (see Figure 1 for the locations of the clusters).",mds,True,findable,0,0,0,0,0,2022-10-30T04:22:21.000Z,2022-10-30T04:22:21.000Z,figshare.ars,otjm,"Geology,FOS: Earth and related environmental sciences","[{'subject': 'Geology'}, {'subject': 'FOS: Earth and related environmental sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['5315032 Bytes'], +10.6084/m9.figshare.c.6650322.v1,Digital undergraduate medical education and patient and carer involvement: a rapid systematic review of current practice,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Involving patients and carers in medical students’ learning aims to centralise the perspective of healthcare users and supports our future medical workforce in the development of key skills. Medical schools are increasingly using digital technology for teaching and it is timely to understand how to maintain patient and carer involvement in this context. Methods Ovid MEDLINE, Ovid EMBASE and medRxiv were searched in October 2020 and reference lists of key articles were hand searched. Eligible studies reported authentic patient or carer involvement in undergraduate medical education where technology was also used. Study quality was assessed by the Mixed Methods Appraisal Tool (MMAT). Levels of patient or carer involvement were assessed using Towle et al.’s (2010) taxonomy, from Level 1 (lowest level) to Level 6 (highest level). Results Twenty studies were included in this systematic review. In 70% of studies, patients and carers featured in video or web-based case scenarios with no interaction between healthcare users and students. The remaining 30% of studies reported real-time interactions between students and patients via remote clinical encounters. Digital teaching sessions involving patients or carers were perceived to be valuable by students and educators, and increased student engagement, patient-centred attitudes, clinical knowledge, and communication skills. No studies reported the perspective of patients or carers. Discussion Digital technology has not yet driven higher levels of patient and carer involvement in medical training. “Live†interactions between students and patients are becoming more common but challenges need addressing to ensure positive experiences for all involved. Future teaching should enhance the role of patients and carers in medical education and support them to overcome any potential barriers to doing so remotely.",mds,True,findable,0,0,0,0,0,2023-05-17T03:24:27.000Z,2023-05-17T03:24:27.000Z,figshare.ars,otjm,"Medicine,Science Policy,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,111714 Mental Health,FOS: Health sciences","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.24483508,Additional file 1 of Cefoxitin versus carbapenems as definitive treatment for extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteremia in intensive care unit: a propensity-matched retrospective analysis,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1. Table S1: Analysis of risk factors for 30-day clinical failure in patients with ESBL-KP bacteremia. Table S2: Matching graph of the propensity score.,mds,True,findable,0,0,0,0,0,2023-11-02T05:00:06.000Z,2023-11-02T05:00:06.000Z,figshare.ars,otjm,"Space Science,Medicine,Microbiology,FOS: Biological sciences,Cancer,Infectious Diseases,FOS: Health sciences","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Microbiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['61375 Bytes'], +10.6084/m9.figshare.c.6252814,Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data,figshare,2022,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Outcomes of postresuscitation shock after cardiac arrest can be affected by targeted temperature management (TTM). A post hoc analysis of the “TTM1 trial†suggested higher mortality with hypothermia at 33 °C. We performed a post hoc analysis of HYPERION trial data to assess potential associations linking postresuscitation shock after non-shockable cardiac arrest to hypothermia at 33 °C on favourable functional outcome. Methods We divided the patients into groups with vs. without postresuscitation (defined as the need for vasoactive drugs) shock then assessed the proportion of patients with a favourable functional outcome (day-90 Cerebral Performance Category [CPC] 1 or 2) after hypothermia (33 °C) vs. controlled normothermia (37 °C) in each group. Patients with norepinephrine or epinephrine > 1 µg/kg/min were not included. Results Of the 581 patients included in 25 ICUs in France and who did not withdraw consent, 339 had a postresuscitation shock and 242 did not. In the postresuscitation-shock group, 159 received hypothermia, including 14 with a day-90 CPC of 1–2, and 180 normothermia, including 10 with a day-90 CPC of 1–2 (8.81% vs. 5.56%, respectively; P = 0.24). After adjustment, the proportion of patients with CPC 1–2 also did not differ significantly between the hypothermia and normothermia groups (adjusted hazards ratio, 1.99; 95% confidence interval, 0.72–5.50; P = 0.18). Day-90 mortality was comparable in these two groups (83% vs. 86%, respectively; P = 0.43). Conclusions After non-shockable cardiac arrest, mild-to-moderate postresuscitation shock at intensive-care-unit admission did not seem associated with day-90 functional outcome or survival. Therapeutic hypothermia at 33 °C was not associated with worse outcomes compared to controlled normothermia in patients with postresuscitation shock. Trial registration ClinicalTrials.gov, NCT01994772",mds,True,findable,0,0,0,0,0,2022-10-18T03:24:07.000Z,2022-10-18T03:24:07.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Physiology,FOS: Biological sciences,Pharmacology,Biotechnology,Cancer,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Physiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}]",, +10.6084/m9.figshare.23551874,A systematic review of pharmacotherapy for attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders,Taylor & Francis,2023,,Text,Creative Commons Attribution 4.0 International,"The data suggests that in children and adolescents, bipolar disorder (BD) and attention deficit hyperactivity disorder (ADHD) may be strongly correlated. Even though drugs for ADHD and BD are largely accepted, there is relatively little research on the management of comorbidity in children and adolescents, particularly in terms of safety. We provide a synthesis of these findings because one hasn’t been made yet. As a primary outcome, we wanted to determine whether stimulant or non-stimulant treatment of children and adolescents with ADHD and comorbid BD was effective. As a secondary outcome, we wanted to determine tolerability, especially the risk of mood switch. The findings of this systematic review suggest that methylphenidate, when used with a mood stabilizer, may be safe and not significantly increase the risk of a manic switch or psychotic symptoms when used to treat ADHD that co-occurs with a BD. In situations where stimulants are ineffective or have low tolerance, atomoxetine also seems to be a good alternative, and also in cases of co-morbid anxiety, oppositional defiant disorder, conduct disorders, ICT disorders, and substance use disorders. Additional research with a higher level of evidence is necessary to corroborate these preliminary findings.",mds,True,findable,0,0,0,0,0,2023-06-21T07:40:07.000Z,2023-06-21T07:40:08.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Neuroscience,Physiology,FOS: Biological sciences,Pharmacology,Biotechnology,Science Policy,Mental Health","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Neuroscience'}, {'subject': 'Physiology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': 'Science Policy'}, {'subject': 'Mental Health'}]",['27108 Bytes'], +10.48380/5662-yk90,From Struggle to Solutions: Understanding the Concerns of People's Groundwater Usage Habits and Environmental Awareness for Sustainable Water Management in Ca Mau Province,Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV),2023,en,Text,,"<p>The Mekong Delta, including Ca Mau province in the south, faces severe land subsidence, attributed in part to the excessive groundwater extraction. Addressing this issue requires finding alternative water sources while considering technical, environmental and social challenges. This study aims to understand the significance of groundwater to the people of Ca Mau, their water usage habits and awareness with environmental issues. Supported by local Provincial People's Committees, a comprehensive survey and group interviews were conducted across 9 districts of Ca Mau province. The research aimed to identify the spatial distribution of the required water management solutions and acceptance levels of alternative water resources. Water samples were collected and analyzed to establish the connection between water quality and people's water usage habits. Groundwater plays a vital role in people’s life, serving various purposes such as washing, cooking, drinking, and other activities. Groundwater usage depends on people's perceptions of its quality. For activities requiring higher levels of hygiene, additional water treatment or alternative water sources are preferred. The analytical approach from general viewpoints to details in this study investigates deeper into the story behind their water usage habits. It emphasizes the need to inform people about environmental challenges and raise awareness of cause-effect relationships. Evaluating alternative water resources and designing new water utilization concepts is based on local demands and willingness to change water-related habits. This research sheds light on people's awareness and concern while providing valuable insights for sustainable water management strategies in the Mekong Delta, specifically in Ca Mau province.</p> +",api,True,findable,0,0,0,0,0,2023-12-11T21:16:02.000Z,2023-12-11T21:16:02.000Z,mcdy.dohrmi,mcdy,,,, +10.6084/m9.figshare.c.6575881.v1,Procalcitonin to reduce exposure to antibiotics and individualise treatment in hospitalised old patients with pneumonia: a randomised study,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Treating pneumonia in old patients remains challenging for clinicians. Moreover, bacterial antimicrobial resistance is a major public health threat. Objective The PROPAGE study evaluated the interest of a strategy using serial measurements of procalcitonin (PCT) to reduce the duration of antibiotic therapy in old patients with pneumonia. Methods PROPAGE took place from Dec.-2013 to Jun.-2016 in eight French geriatric units. It was a prospective, comparative, randomised, open-label study involving old patients (≥ 80 years) who had initiated antibiotic treatment for pneumonia in the previous 48 h. PCT was monitored in all patients and two decision-making PCT-based algorithms guided antibiotic therapy in patients from the PCT group. Results 107 patients were randomised (PCT, n = 50; Control, n = 57). Antibiotic therapy exposure was reduced in the PCT group as compared to the Control group (median duration of antibiotic therapy, 8 vs. 10 days [rank-test, p = 0.001]; antibiotic persistence rates on Days 6 and 8, 54% and 44% vs. 91% and 72%) and no significant difference was found in recovery rate (84% vs. 89.5%; Pearson Chi² test, p = 0.402). Conclusion Although, the superiority of the strategy was not tested using a composite criterion combining antibiotic therapy duration and recovery rate was not tested due to the small sample size, the present study showed that monitoring associated with PCT-guided algorithm could help shorten antibiotic treatment duration in the very old patients without detrimental effects. Measuring PCT levels between Day 4 and Day 6 could be helpful when making the decision regarding antibiotic discontinuation. Trial registration NCT02173613. This study was first registered on 25/06/2014.",mds,True,findable,0,0,0,0,0,2023-04-13T09:42:57.000Z,2023-04-13T09:42:57.000Z,figshare.ars,otjm,"Space Science,Medicine,Immunology,FOS: Clinical medicine,Cancer,111714 Mental Health,FOS: Health sciences,110309 Infectious Diseases","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '110309 Infectious Diseases', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}]",, +10.5061/dryad.rm2n41j,"Data from: Diet shifts by adult flightless dung beetles Circellium bacchus, revealed using DNA metabarcoding, reflect complex life histories",Dryad,2018,en,Dataset,Creative Commons Zero v1.0 Universal,"Life history changes may change resource use. Such shifts are not well understood in the dung beetles, despite recognized differences in larval and adult feeding ability. We use the flightless dung beetle Circellium bacchus to explore such shifts, identifying dung sources of adults using DNA metabarcoding, and comparing these with published accounts of larval dung sources. C. bacchus is traditionally considered to specialise on the dung of large herbivores for both larval and adult feeding. We successfully extracted mammal DNA from 151 adult C. bacchus fecal samples, representing 16 mammal species (ranging from elephants to small rodents), many of which are hitherto undescribed in the diet. Adult C. bacchus showed clear dung source preferences, especially for large herbivores inhabiting dense-cover vegetation. Our approach also confirmed the presence of cryptic taxa in the study area, and we propose this may be used for biodiversity survey and monitoring purposes. Murid rodent feces were the most commonly fed-upon dung source (77.5%) for adult C. bacchus, differing markedly from the large and megaherbivore dung sources used for larval rearing. These findings support the hypothesis of life history-specific shifts in resource use in dung beetles, and reveal a hitherto unsuspected, but ecologically important, role of these dung beetles in consuming rodent feces. The differences in feeding abilities of the larval and adult life history stages have profound consequences for their resource use and foraging strategies, and hence the ecological role of dung beetles. This principle and its ecological consequences should be explored in other scarabaeids.",mds,True,findable,185,15,1,1,0,2018-07-02T15:51:09.000Z,2018-07-02T15:51:16.000Z,dryad.dryad,dryad,"Equus burchellii,Rhabdomys pumilio,Cephalophus sp.,biodiversity survey,Next Generation Sequencing,Tragelaphus strepsiceros,Canis mesomelas,rodent feces,Loxodonta africana,Circellium bacchus,Potamochoerus larvatus,Modern data,Syncerus caffer,Michaelamys sp.,Phacochoerus africanus,Otomys sp.,Philantomba monticola,Holocene,Tragelaphus scriptus,Hystrix africaeaustralis","[{'subject': 'Equus burchellii'}, {'subject': 'Rhabdomys pumilio'}, {'subject': 'Cephalophus sp.'}, {'subject': 'biodiversity survey'}, {'subject': 'Next Generation Sequencing'}, {'subject': 'Tragelaphus strepsiceros'}, {'subject': 'Canis mesomelas'}, {'subject': 'rodent feces'}, {'subject': 'Loxodonta africana'}, {'subject': 'Circellium bacchus'}, {'subject': 'Potamochoerus larvatus'}, {'subject': 'Modern data'}, {'subject': 'Syncerus caffer'}, {'subject': 'Michaelamys sp.'}, {'subject': 'Phacochoerus africanus'}, {'subject': 'Otomys sp.'}, {'subject': 'Philantomba monticola'}, {'subject': 'Holocene'}, {'subject': 'Tragelaphus scriptus'}, {'subject': 'Hystrix africaeaustralis'}]",['9074554 bytes'], +10.25502/synk-yv41/d,CSAT projects Exploratory Survey,International Institute of Tropical Agriculture (IITA),2022,en,Dataset,CC-By 4.0,"The West African Sahel and dry savannahs cover a large northern sector of the sub-region from Nigeria through Benin, Niger, Burkina Faso, Mali, to Senegal where natural resource limitations, especially water scarcity and land degradation, are expected to be exacerbated by climate change. The main goal of the proposed project is to introduce climate smart agricultural technologies and innovations in the Sahel and dry savannah regions of Mali and Niger that will improve rural livelihoods and food security. In the first of the two components of the project, we will use innovation platforms (IPs) to scale out exisitng technologies along the value chain of key commodities. In Niger the delivery mechanisms that the current Norwegian project (RED/SAACC-Niger) is applying will also be adopted. In the second project component we will conduct research to develop and adapt additional technological options to expand the pool from which farmers and other value chain actors get to choose from. ",fabricaForm,True,findable,0,0,0,0,0,2022-08-18T14:38:51.000Z,2022-08-18T14:38:52.000Z,bl.iita,ainb,,,,['CSV'] +10.6084/m9.figshare.c.6797383,Determination of different social groups’ level of knowledge about malaria in a multicultural Amazonian cross-border context,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background A steady decline in the number of cases of malaria was observed in the 2000s in French Guiana. This enabled regional health policies to shift their public health goal from control to elimination. To include inhabitants in this strategy, the main objective of this study was to describe knowledge about malaria, and related attitudes and practices in persons living in the French Guiana border. Methods We conducted a survey in people over 15 years old living in the twelve neighbourhoods of Saint-Georges de l’Oyapock with the highest malaria incidence. It comprised a 147-item questionnaire which collected data on socio-demographic characteristics and included a Knowledge Attitude and Practices survey on malaria. Knowledge-related data were studied using exploratory statistical methods to derive summary variables. A binary variable assessing level of knowledge was proposed and then assessed using exploratory approaches. Results The mean age of the 844 participants was 37.2 years [15.8], the male/female sex ratio was 0.8. In terms of nationality, 485 (57.5%) participants were Brazilian and 352 (41.7%) French. One third (305, 36.1%) spoke Brazilian Portuguese as their native language, 295 (34.9%) the Amerindian language Palikur, 36 (4.3%) French. The symptoms of malaria and prevention means were poorly known by 213 (25.2%) and 378 (44.8%) respondents, respectively. A quarter (206, 24.4%) did not know that malaria can be fatal. Overall, 251 people (29.7%) had an overall poor level of knowledge about malaria. Being under 25 years old, living in a native Amerindian neighbourhood, having an Amerindian mother tongue language, having risk behaviours related to gold mining were significantly associated with a poor level of knowledge. Conclusions This study is the first to describe the poor level of knowledge about malaria in populations living in the malaria endemic border area along the Oyapock river in French Guiana. Results will allow to reinforce, to diversify and to culturally adapt prevention messages and health promotion to increase their effectiveness with a view to quickly reaching the goal of malaria elimination through empowerment.",mds,True,findable,0,0,0,0,0,2023-08-20T03:11:04.000Z,2023-08-20T03:11:04.000Z,figshare.ars,otjm,"Biological Sciences not elsewhere classified,Science Policy","[{'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Science Policy'}]",, +10.6084/m9.figshare.22625626,"Additional file 7 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 7.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:18.000Z,2023-04-13T18:56:18.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['122896 Bytes'], +10.6084/m9.figshare.22617740,"Additional file 1 of Individual and environmental determinants associated with longer times to access pediatric rheumatology centers for patients with juvenile idiopathic arthritis, a JIR cohort study",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1. Location of the 20 pediatric rheumatology centers (using Google Maps).,mds,True,findable,0,0,0,0,0,2023-04-13T16:35:35.000Z,2023-04-13T16:35:36.000Z,figshare.ars,otjm,"Medicine,Biotechnology,Ecology,FOS: Biological sciences,Immunology,FOS: Clinical medicine,Cancer,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Biotechnology'}, {'subject': 'Ecology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}]",['99200 Bytes'], +10.6084/m9.figshare.24091564.v1,Additional file 1 of Survey of adolescents’ needs and parents’ views on sexual health in juvenile idiopathic arthritis,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary Material 1,mds,True,findable,0,0,0,0,0,2023-09-06T17:23:03.000Z,2023-09-06T17:23:03.000Z,figshare.ars,otjm,"Medicine,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}]",['309248 Bytes'], +10.6084/m9.figshare.22625608,"Additional file 1 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:32.000Z,2023-04-13T18:56:32.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['1508179 Bytes'], +10.6084/m9.figshare.22735402.v1,"Additional file 2 of Multiple trauma in pregnant women: injury assessment, fetal radiation exposure and mortality. A multicentre observational study",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary Material 2,mds,True,findable,0,0,0,0,0,2023-05-03T03:19:16.000Z,2023-05-03T03:19:17.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Biotechnology,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Developmental Biology,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Biotechnology'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Developmental Biology'}, {'subject': 'Science Policy'}]",['22640 Bytes'], +10.5281/zenodo.10200549,Design and optimization of a Chloride Molten Salt Fast Reactor,Zenodo,2023,en,ConferenceProceeding,Creative Commons Attribution 4.0 International,"This paper presents several studies for the design and optimization of a 3GWth breeder Molten Salt Fast Reactor using chloride salts and the uranium cycle (Cl-MSFR). Results lead to a configuration of 45m3 of NaCl-depUCl3-(spent UOX fuel TRUs)Cl3 for the fuel salt, along with a fertile blanket of 80cm of width filled with NaCl-depUCl3 in which a small amount of spent MOX fuel TRUs is dissolved for spent MOX reuse and proliferation resistance. A reprocessing scheme dedicated to the cleaning of these chloride salts is proposed. Finally, preliminary studies on Cl-MSFR deployment don't show any constraints on matter availability and present a good synergy with PWRs.",api,True,findable,0,0,0,0,0,2023-11-23T11:24:14.000Z,2023-11-23T11:24:14.000Z,cern.zenodo,cern,,,, +10.5061/dryad.dh478,"Data from: Paying for conservation: a bioeconomic analysis of the effects of land management options on the viability of an endangered species, Eryngium alpinum",Dryad,2019,en,Dataset,Creative Commons Zero v1.0 Universal,"1. Land management is critical for biodiversity conservation in mountain grasslands. It should be both ecologically effective and economically efficient. We provide an economic analysis of different options (spring and autumn grazing, mowing and abandonment) and their effects on population viability of a rare plant species, Eryngium alpinum (Apiaceae), in two French mountain grassland sites (Fournel and Pralognan). 2. Using data collected in a ten-year, individual-based demographic study, we estimated the effects of land management options on the population growth rate and simulated the effect of combinations of options. Income earned through each option was estimated using data on associated costs (price of consumables, working time, wages) and benefits (forage production, quality and price), and we assessed the economic effects of agri-enviro nment subsidies (AESs). We also simulated the effects of increased frequencies of extreme climatic events (such as the 2003 heatwave). 3. Spring grazing was the worst option for E. alpinum demography but the best in economic terms, as it provided net positive incomes. Autumn grazing was the best option, resulting in positive growth rates and incomes, even if the latter were lower than for spring grazing. Mowing was the second best option for demography but resulted in economic losses for farmers. Abandonment provided zero income and was not favourable to population growth. 4. In Fournel, AESs allowed for economically and ecologically near-optimal combinations of management options. In Pralognan, alternating years of grazing with mowing resulted in an acceptable compromise, with positive growth rates and incomes, but AESs were not sufficient to cover the opportunity cost of spring and autumn grazing. Mowing was also unattractive because of the inaccessibility of the site and impossibility to recover the hay to make forage. 5. Simulations with increased frequency of extreme climatic events resulted in negative growth rates in Pralognan, questioning the continuation of AESs in extinction-prone populations. 6. Synthesis and applications. The conservation effectiveness and economic efficiency of grassland management could be improved by alternating practices over several years. However, existing agri-environment subsidies would barely be sufficient to increase uptake of the most favourable land management options for biodiversity.",mds,True,findable,165,10,1,1,0,2018-01-17T15:48:18.000Z,2018-01-17T15:48:19.000Z,dryad.dryad,dryad,"Eryngium alpinum,mowing,heatwave effects,agri-encironmental measures","[{'subject': 'Eryngium alpinum'}, {'subject': 'mowing'}, {'subject': 'heatwave effects'}, {'subject': 'agri-encironmental measures'}]",['17600 bytes'], +10.6084/m9.figshare.c.6642960.v1,Phenotype and imaging features associated with APP duplications,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background APP duplication is a rare genetic cause of Alzheimer disease and cerebral amyloid angiopathy (CAA). We aimed to evaluate the phenotypes of APP duplications carriers. Methods Clinical, radiological, and neuropathological features of 43 APP duplication carriers from 24 French families were retrospectively analyzed, and MRI features and cerebrospinal fluid (CSF) biomarkers were compared to 40 APP-negative CAA controls. Results Major neurocognitive disorders were found in 90.2% symptomatic APP duplication carriers, with prominent behavioral impairment in 9.7%. Symptomatic intracerebral hemorrhages were reported in 29.2% and seizures in 51.2%. CSF Aβ42 levels were abnormal in 18/19 patients and 14/19 patients fulfilled MRI radiological criteria for CAA, while only 5 displayed no hemorrhagic features. We found no correlation between CAA radiological signs and duplication size. Compared to CAA controls, APP duplication carriers showed less disseminated cortical superficial siderosis (0% vs 37.5%, p = 0.004 adjusted for the delay between symptoms onset and MRI). Deep microbleeds were found in two APP duplication carriers. In addition to neurofibrillary tangles and senile plaques, CAA was diffuse and severe with thickening of leptomeningeal vessels in all 9 autopsies. Lewy bodies were found in substantia nigra, locus coeruleus, and cortical structures of 2/9 patients, and one presented vascular amyloid deposits in basal ganglia. Discussion Phenotypes associated with APP duplications were heterogeneous with different clinical presentations including dementia, hemorrhage, and seizure and different radiological presentations, even within families. No apparent correlation with duplication size was found. Amyloid burden was severe and widely extended to cerebral vessels as suggested by hemorrhagic features on MRI and neuropathological data, making APP duplication an interesting model of CAA.",mds,True,findable,0,0,0,0,0,2023-05-12T03:40:51.000Z,2023-05-12T03:40:51.000Z,figshare.ars,otjm,"Biochemistry,Medicine,Cell Biology,Neuroscience,Science Policy","[{'subject': 'Biochemistry'}, {'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Neuroscience'}, {'subject': 'Science Policy'}]",, +10.6084/m9.figshare.c.6235037.v1,Prognosis of lasso-like penalized Cox models with tumor profiling improves prediction over clinical data alone and benefits from bi-dimensional pre-screening,figshare,2022,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Prediction of patient survival from tumor molecular ‘-omics’ data is a key step toward personalized medicine. Cox models performed on RNA profiling datasets are popular for clinical outcome predictions. But these models are applied in the context of “high dimensionâ€, as the number p of covariates (gene expressions) greatly exceeds the number n of patients and e of events. Thus, pre-screening together with penalization methods are widely used for dimensional reduction. Methods In the present paper, (i) we benchmark the performance of the lasso penalization and three variants (i.e., ridge, elastic net, adaptive elastic net) on 16 cancers from TCGA after pre-screening, (ii) we propose a bi-dimensional pre-screening procedure based on both gene variability and p-values from single variable Cox models to predict survival, and (iii) we compare our results with iterative sure independence screening (ISIS). Results First, we show that integration of mRNA-seq data with clinical data improves predictions over clinical data alone. Second, our bi-dimensional pre-screening procedure can only improve, in moderation, the C-index and/or the integrated Brier score, while excluding irrelevant genes for prediction. We demonstrate that the different penalization methods reached comparable prediction performances, with slight differences among datasets. Finally, we provide advice in the case of multi-omics data integration. Conclusions Tumor profiles convey more prognostic information than clinical variables such as stage for many cancer subtypes. Lasso and Ridge penalizations perform similarly than Elastic Net penalizations for Cox models in high-dimension. Pre-screening of the top 200 genes in term of single variable Cox model p-values is a practical way to reduce dimension, which may be particularly useful when integrating multi-omics.",mds,True,findable,0,0,0,0,0,2022-10-06T07:36:19.000Z,2022-10-06T07:36:20.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Pharmacology,Immunology,FOS: Clinical medicine,69999 Biological Sciences not elsewhere classified,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Cancer","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",, +10.6084/m9.figshare.22027566.v1,Students’ and tutors’ experiences of remote ‘student–patient’ consultations,Taylor & Francis,2023,,Text,Creative Commons Attribution 4.0 International,"Remote consulting has become part of the medical student clinical experience in primary care, but little research exists regarding the impact on learning. To describe the experiences of General Practitioner (GP) educators and medical students in using student-led remote consultations as an educational tool. A qualitative, explorative study conducted at four UK medical schools. GP educators and medical students were purposively sampled and interviewed. Nine themes arose: practical application, autonomy, heuristics, safety, triage of undifferentiated patients, clinical reasoning, patient inclusion in student education, student–patient interaction, and student–doctor interaction. Remote consulting has become part of the clinical placement experience. This has been found to expose students to a wider variety of clinical presentations. Verbal communication, history-taking, triage, and clinical reasoning skills were practised through remote consulting, but examination skills development was lacking. Students found building rapport more challenging, although this was mitigated by having more time with patients. Greater clinical risk was perceived in remote consulting, which had potential to negatively impact students’ psychological safety. Frequent debriefs could ameliorate this risk and positively impact student–doctor relationships. Student autonomy and independence increased due to greater participation and responsibility. Pre-selection of patients could be helpful but had potential to expose students to lower complexity patients. Practice pointsRemote consulting confers unique educational benefits.Remote consulting can help develop history-taking and communication skills, as well as clinical reasoning skills.The psychological safety of the student and the supervisory risk of the tutor can be impacted by remote consulting, but frequent debriefs between the student and tutor can help mitigate this risk.Learning how to conduct remote, and face-to-face consultations is important in medical education. Practice points Remote consulting confers unique educational benefits. Remote consulting can help develop history-taking and communication skills, as well as clinical reasoning skills. The psychological safety of the student and the supervisory risk of the tutor can be impacted by remote consulting, but frequent debriefs between the student and tutor can help mitigate this risk. Learning how to conduct remote, and face-to-face consultations is important in medical education.",mds,True,findable,0,0,0,1,0,2023-02-06T19:20:05.000Z,2023-02-06T19:20:05.000Z,figshare.ars,otjm,"Medicine,Neuroscience,Biotechnology,Science Policy,Mental Health,Hematology,Plant Biology,FOS: Biological sciences","[{'subject': 'Medicine'}, {'subject': 'Neuroscience'}, {'subject': 'Biotechnology'}, {'subject': 'Science Policy'}, {'subject': 'Mental Health'}, {'subject': 'Hematology'}, {'subject': 'Plant Biology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['17511 Bytes'], +10.5061/dryad.9kd51c5q1,Raw sequencing data and ngsfilters for snow track eDNA samples,Dryad,2023,en,Dataset,Creative Commons Zero v1.0 Universal,"Continued advancements in environmental DNA (eDNA) research have made it possible to access intraspecific variation from eDNA samples, opening new opportunities to expand non-invasive genetic studies of wildlife populations. However, the use of eDNA samples for individual genotyping, as typically performed in non-invasive genetics, still remains elusive. We present the first successful individual genotyping of eDNA obtained from snow tracks of three large carnivores: brown bear (Ursus arctos), European lynx (Lynx lynx) and wolf (Canis lupus). DNA was extracted using a protocol for isolating water eDNA and genotyped using amplicon sequencing of short tandem repeats (STR) and, for brown bear, a sex marker, on a high-throughput sequencing platform. Individual genotypes were obtained for all species, but genotyping performance differed among samples and species. The proportion of samples genotyped to individuals was higher for brown bear samples (5/7) than for wolf (7/10) and lynx (4/9), but locus genotyping success was greater for brown bear (0.88). Results for three species show that reliable individual genotyping, including sex identification, is now possible from eDNA in snow tracks, underlining its vast potential to complement the non-invasive genetic methods used for wildlife. To fully leverage the application of snow track eDNA, improved understanding of the ideal species- and site-specific sampling conditions, as well as laboratory methods promoting genotyping success are needed. This will also inform efforts to retrieve and type nuclear DNA from other eDNA samples, thereby advancing eDNA–based individual and population-level studies.",mds,True,findable,52,5,0,0,0,2023-11-09T18:55:11.000Z,2023-11-09T18:55:12.000Z,dryad.dryad,dryad,"FOS: Biological sciences,FOS: Biological sciences,eDNA-based population studies,high-throughput STR genotyping by sequencing,individual identification,large carnivores,non-invasive genetics,snow track sampling","[{'subject': 'FOS: Biological sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'eDNA-based population studies'}, {'subject': 'high-throughput STR genotyping by sequencing'}, {'subject': 'individual identification'}, {'subject': 'large carnivores'}, {'subject': 'non-invasive genetics'}, {'subject': 'snow track sampling'}]",['10743439525 bytes'], +10.6084/m9.figshare.c.6592129,"Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Moyamoya angiopathy (MMA) is a rare cerebrovascular condition leading to stroke. Mutations in 15 genes have been identified in Mendelian forms of MMA, but they explain only a very small proportion of cases. Our aim was to investigate the genetic basis of MMA in consanguineous patients having unaffected parents in order to identify genes involved in autosomal recessive MMA. Methods Exome sequencing (ES) was performed in 6 consecutive consanguineous probands having MMA of unknown etiology. Functional consequences of variants were assessed using western blot and protein 3D structure analyses. Results Causative homozygous variants of NOS3, the gene encoding the endothelial nitric oxide synthase (eNOS), and GUCY1A3, the gene encoding the alpha1 subunit of the soluble guanylate cyclase (sGC) which is the major nitric oxide (NO) receptor in the vascular wall, were identified in 3 of the 6 probands. One NOS3 variant (c.1502 + 1G > C) involves a splice donor site causing a premature termination codon and leads to a total lack of eNOS in endothelial progenitor cells of the affected proband. The other NOS3 variant (c.1942 T > C) is a missense variant located into the flavodoxine reductase domain; it is predicted to be destabilizing and shown to be associated with a reduction of eNOS expression. The GUCY1A3 missense variant (c.1778G > A), located in the catalytic domain of the sGC, is predicted to disrupt the tridimensional structure of this domain and to lead to a loss of function of the enzyme. Both NOS3 mutated probands suffered from an infant-onset and severe MMA associated with posterior cerebral artery steno-occlusive lesions. The GUCY1A3 mutated proband presented an adult-onset MMA associated with an early-onset arterial hypertension and a stenosis of the superior mesenteric artery. None of the 3 probands had achalasia. Conclusions We show for the first time that biallelic loss of function variants in NOS3 is responsible for MMA and that mutations in NOS3 and GUCY1A3 are causing fifty per cent of MMA in consanguineous patients. These data pinpoint the essential role of the NO pathway in MMA pathophysiology.",mds,True,findable,0,0,0,0,0,2023-04-13T14:39:37.000Z,2023-04-13T14:47:59.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.c.6424523,Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃,Optica Publishing Group,2023,,Collection,Creative Commons Attribution 4.0 International,"By performing Bidirectionnal Reflectance Distribution Function (BRDF) measurements, we have identified back-scattering as the main phenomena involved in the appearance of dry nano-crystallized powders. We introduce an analytical and physically-based BRDF model that relies on the enhanced back-scattering theory to accurately reproduce BRDF measurements. These experimental data were performed on optically thick layers of dry powders with various grains’ morphologies. Our results are significantly better than the ones obtained with previous models. Our model has been validated against the BRDF measurements of multiple synthesized nano-crystallized and mono-disperse 𛼠− Fe2O3 hematite powders. Finally, we discuss the ability of our model to be extended to other materials or more complex powder morphologies.",mds,True,findable,0,0,0,0,0,2023-09-01T15:03:20.000Z,2023-09-01T15:03:21.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],, +10.5061/dryad.b2rbnzsfw,Dataset: Inverse responses of species richness and niche specialization to human development,Dryad,2021,en,Dataset,Creative Commons Zero v1.0 Universal,"Humans impact biodiversity by altering land use and introducing nonnative species. Yet the extent to which coexistence processes, such as competition and niche shifts, mediate these relationships is not clear. This dataset was used in a study that aims to compare how human development influences wetland plant diversity by examining patterns of species richness, niche specialization, and nonnative species occurrences along a human development gradient. This dataset can be used to analyzed species richness and niche specialization (a measure of the range of human development extents over which a species occurs) patterns from species occurrence data across 1582 wetlands in Alberta, Canada. Associations between human development extent and species richness, niche specialization, and nonnative species can be tested using linear mixed models. Also, nonmetric multidimensional scaling ordination can be applied from raw data (see usage notes) to examine whether community composition differed among wetlands surrounded by different human development extents. Note that human development data are accessible only through a data sharing agreement with ABMI. See the readme document for more details on how to obtain assess to these data. Results of these analyses can be found in the corresponding publication: Inverse responses of species richness and niche specialization to human development, Journal of Biogeography. https://doi.org/10.1111/jbi.14240",mds,True,findable,183,26,0,1,0,2021-07-26T20:01:07.000Z,2021-07-26T20:01:08.000Z,dryad.dryad,dryad,"Ecology,FOS: Biological sciences,ABMI,alien / exotic / non-native species,Richness,Alberta,Canada,Diversity patterns,communities,assembly rules,peatlands","[{'subject': 'Ecology', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'ABMI'}, {'subject': 'alien / exotic / non-native species'}, {'subject': 'Richness'}, {'subject': 'Alberta', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}, {'subject': 'Canada', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}, {'subject': 'Diversity patterns'}, {'subject': 'communities'}, {'subject': 'assembly rules'}, {'subject': 'peatlands'}]",['273198 bytes'], +10.57757/iugg23-4587,"Perturbations of free-field seismic recordings caused by coupling slabs, short wavelength topography and soil-structure interaction: Preliminary results from empirical studies",GFZ German Research Centre for Geosciences,2023,en,ConferencePaper,Creative Commons Attribution 4.0 International,"<!--!introduction!--><b></b><p>Recording ground motions is essential to estimate the seismic hazard. Signals from the databases are often considered to be in free-field, i.e. at the natural surface of the ground, without disturbances due to buildings or neighbouring structures. Nevertheless, the analysis of seismological networks has highlighted many installation modalities, including the coupling of seismometers, coexist. Recent studies have also shown that the installation conditions of these seismological stations can have a significant impact on the recorded motion, compared to true free-field measurements. Similarly, the effects of topography on a metric or decametric scale are poorly studied but also impact on the measurement at high frequency.</p>This study focuses on a qualification of the effects of installation of seismometers, through several experiments that have been set up in Greece, mainly in Cephalonia Island, chosen for its high seismicity. The influence of the coupling methods of the seismometers is studied using the experiment called ""ArgoSlab"", where around thirty seismometers have been installed on slab or on seismic pillar of different size and shape, outdoor or sheltered, and compared to the recordings obtained by free-field sensors. The effect of topography at the metric and decametric scale is addressed by the analysis of about fifteen seismometers installed in the hill of Krani, near Argostoli (« ArgoScarp » experiment). Finally, the analysis of soil-structure interaction is carried out by the comparison of sets of sensors in free-field (several tens of metres from the building), very close to buildings and inside buildings (basement and top floor).",fabricaForm,True,findable,0,0,0,0,0,2023-07-03T19:58:15.000Z,2023-07-11T17:11:05.000Z,gfz.iugg2023,gfz,,,, +10.6084/m9.figshare.22625623.v1,"Additional file 6 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 6.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:08.000Z,2023-04-13T18:48:08.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['190912 Bytes'], +10.6084/m9.figshare.23994604.v1,Additional file 2 of Determination of different social groups’ level of knowledge about malaria in a multicultural Amazonian cross-border context,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 2: Appendix 2. Factor analyses of multiple-choice variables assessing knowledge of malaria prevention methods,mds,True,findable,0,0,0,0,0,2023-08-20T03:11:03.000Z,2023-08-20T03:11:03.000Z,figshare.ars,otjm,"Biological Sciences not elsewhere classified,Science Policy","[{'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Science Policy'}]",['20317 Bytes'], +10.5061/dryad.0rxwdbrv7,Through the taste buds of a large herbivore: foodscape modeling contributes to an understanding of forage selection processes,Dryad,2019,en,Dataset,Creative Commons Zero v1.0 Universal,"How large herbivores track resource quantity and quality through time has formed the core of an abundance of literature on migratory populations in recent decades. Yet, relating foraging processes and habitat selection patterns in resident populations, where spatial heterogeneity of food resources is fineâ€grained and/or where the portion of edible plants (i.e. the foodscape) is low, is challenging. We addressed this issue in a mountain population of chamois Rupicapra rupicapra, an intermediate feeder, whose individuals do not migrate. We relied on a rare combination of data on habitat use of 50 GPSâ€collared females and data on the quantity (biomass) and quality (phenology) of edible resources in their landscape, derived from field sampling of vegetation, remote sensing, and diet (DNA barcoding). The foodscape of the chamois was composed of a low proportion of the available biomass (<17%), including relatively highâ€quality plants, with low spatial covariation between plant phenology and biomass. Chamois avoided areas with a low edible biomass (where the intake rate may be too low) and focused on areas with plants at approximately the flowering stage, whatever the average plant phenological stage available. Due to this constant preference for flowering plants, home range selection ratios therefore shifted during the summer from a selection of more advanced plants in June to their avoidance in August. When the phenology scores of all plants available, rather than edible plants only, were considered, areas with relatively more advanced plants were selected all summer long. This exemplifies that, when traits from edible plants are different from those of all plants available, it is crucial to consider the actual foodscape to decipher forage and habitat selection processes. By integrating speciesâ€specific dimensions of resources in habitat selection studies, we believe understanding of the foraging processes will be improved.",mds,True,findable,144,12,0,1,0,2019-10-24T22:32:39.000Z,2019-10-24T22:32:39.000Z,dryad.dryad,dryad,"chamois,rupicapra rupicapra,quality-quantity trade-off","[{'subject': 'chamois'}, {'subject': 'rupicapra rupicapra'}, {'subject': 'quality-quantity trade-off'}]",['63172 bytes'], +10.6084/m9.figshare.22625617.v1,"Additional file 4 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 4.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:12.000Z,2023-04-13T18:48:12.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['139801 Bytes'], +10.6084/m9.figshare.22625629.v1,"Additional file 8 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 8.,mds,True,findable,0,0,0,0,0,2023-04-13T18:48:04.000Z,2023-04-13T18:48:04.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['984563 Bytes'], +10.6084/m9.figshare.24188536.v1,Transformative learning in clinical reasoning: a meta-synthesis in undergraduate primary care medical education,Taylor & Francis,2023,,Text,Creative Commons Attribution 4.0 International,"Clinical reasoning is a vital medical education skill, yet its nuances in undergraduate primary care settings remain debated. This systematic review explores clinical reasoning teaching and learning intricacies within primary care. We redefine clinical reasoning as dynamically assimilating and prioritising synthesised patient, significant other, or healthcare professional information for diagnoses or non-diagnoses. This focused meta-synthesis applies transformative learning theory to primary care clinical reasoning education. A comprehensive analysis of 29 selected studies encompassing various designs made insights into clinical reasoning learning dimensions visible. Primary care placements in varying duration and settings foster diverse instructional methods like bedside teaching, clinical consultations, simulated clinics, virtual case libraries, and more. This review highlights the interplay between disease-oriented and patient-centred orientations in clinical reasoning learning. Transformative learning theory provides an innovative lens, revealing stages of initiation, persistence, time and space, and competence and confidence in students’ clinical reasoning evolution. Clinical teachers guide this transformation, adopting roles as fortifiers, connoisseurs, mediators, and monitors. Patient engagement spans passive to active involvement, co-constructing clinical reasoning. The review underscores theoretical underpinnings’ significance in shaping clinical reasoning pedagogy, advocating broader diversity. Intentional student guidance amid primary care complexities is vital. Utilising transformative learning, interventions bridging cognitive boundaries enhance meaningful clinical reasoning learning experiences. This study contributes insights for refining pedagogy, encouraging diverse research, and fostering holistic clinical reasoning development.",mds,True,findable,0,0,0,1,0,2023-09-24T15:20:05.000Z,2023-09-24T15:20:06.000Z,figshare.ars,otjm,"Medicine,Neuroscience,Biotechnology,Cancer,Mental Health,Hematology,Infectious Diseases,FOS: Health sciences","[{'subject': 'Medicine'}, {'subject': 'Neuroscience'}, {'subject': 'Biotechnology'}, {'subject': 'Cancer'}, {'subject': 'Mental Health'}, {'subject': 'Hematology'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['44790 Bytes'], +10.6084/m9.figshare.22075664.v1,Supplementary document for Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃ - 6292687.pdf,Optica Publishing Group,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary model information and results,mds,True,findable,0,0,0,0,0,2023-09-01T15:03:20.000Z,2023-09-01T15:03:20.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],['13982355 Bytes'], +10.5061/dryad.zkh189382,Effects of soil preservation for biodiversity monitoring using environmental DNA,Dryad,2020,en,Dataset,Creative Commons Zero v1.0 Universal,"Environmental DNA metabarcoding is becoming a key tool for biodiversity monitoring over large geographical or taxonomic scales and for elusive taxa like soil organisms. Increasing sample sizes and interest in remote or extreme areas often require the preservation of soil samples and thus deviations from optimal standardized protocols. However, we still ignore the impact of different methods of soil sample preservation on the results of metabarcoding studies and there is no guidelines for best practices so far. Here, we assessed the impact of four methods of soil sample preservation commonly used in metabarcoding studies (preservation at room temperature for 6h, preservation at 4°C for three days, desiccation immediately after sampling and preservation for 21 days, and desiccation after 6h at room temperature and preservation for 21 days). For each preservation method, we benchmarked resulting estimates of taxon diversity and community composition of three different taxonomic groups (bacteria, fungi and eukaryotes) in three different habitats (forest, river bank and grassland) against results obtained under optimal conditions (i.e. extraction of eDNA right after sampling). Overall, the different preservation methods only marginally impaired results and only under certain conditions. When rare taxa were considered, we detected small but significant changes in MOTU richness of bacteria, fungi and eukaryotes across treatments, while the exclusion of rare taxa led to robust results across preservation methods. The differences in community structure among habitats were evident for all treatments, and the communities retrieved using the different preservation conditions were extremely similar. We propose guidelines on the selection of the optimal soil sample preservation conditions for metabarcoding studies, depending on the practical constraints, costs and ultimate research goals.",mds,True,findable,213,22,0,1,0,2020-09-24T04:54:08.000Z,2020-09-24T04:54:09.000Z,dryad.dryad,dryad,"sample storage,MOTU richness,α and β diversity,microbial communities","[{'subject': 'sample storage'}, {'subject': 'MOTU richness'}, {'subject': 'α and β diversity'}, {'subject': 'microbial communities'}]",['7014998982 bytes'], +10.5061/dryad.2547d7wr9,Demographic inferences and climatic niche modeling shed light on the evolutionary history of the emblematic cold-adapted Apollo butterfly at regional scale,Dryad,2021,en,Dataset,Creative Commons Zero v1.0 Universal,"Cold-adapted species escape climate warming by latitudinal and/or altitudinal range shifts, and currently occur in Southern Europe in isolated mountain ranges within ‘sky islands. Here we studied the genetic structure of the Apollo butterfly in five such alpine islands (above 1000 m) in France, and infer its demographic history since the last interglacial, using single nucleotide polymorphisms (ddRADseq SNPs). The Auvergne and Alps populations show strong genetic differentiation but not alpine massifs, although separated by deep valleys. Combining three complementary demographic inference methods and species distribution models (SDMs) we show that the LIG period was highly defavorable for Apollo that probably survived in small population in the highest summits of Auvergne. The population shifted downslope and expanded eastward between LIG and LGM throughout the large climatically suitable Rhône valley between the glaciated summits of Auvergne and Alps. The Auvergne and Alps populations started diverging before the LGM but remained largely connected till the mid-Holocene. Population decline in Auvergne was more gradual but started before (~7 kya versus 800 ya), and was much stronger with current population size ten times lower than in the Alps. In the Alps, the low genetic structure and limited evidence for isolation by distance suggest a non-equilibrium metapopulation functioning. The core Apollo population experienced cycles of contraction-expansion with climate fluctuations with largely inter-connected populations over time according to a ‘metapopulation-pulsar’ functioning. This study demonstrates the power of combining demographic inferences and SDMs to determine past and future evolutionary trajectories of an endangered species at a regional scale.",mds,True,findable,116,12,0,0,0,2021-10-18T06:05:50.000Z,2021-10-18T06:05:51.000Z,dryad.dryad,dryad,"FOS: Biological sciences,FOS: Biological sciences","[{'subject': 'FOS: Biological sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['1369000 bytes'], +10.6084/m9.figshare.23816832.v1,Supplementary document for Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃ - 6551122.pdf,Optica Publishing Group,2023,,Text,Creative Commons Attribution 4.0 International,Supplemental document.,mds,True,findable,0,0,0,0,0,2023-09-01T15:03:20.000Z,2023-09-01T15:03:20.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],['11241094 Bytes'], +10.5061/dryad.cv45n3b,"Data from: Circadian periodicity in space use by ungulates of temperate regions: how much, when, and why?",Dryad,2019,en,Dataset,Creative Commons Zero v1.0 Universal,"1. When they visit and revisit specific areas, animals may reveal what they need from their home range and how they acquire information. The temporal dimension of such movement recursions, i.e., periodicity, is however rarely studied, yet potentially bears a species, population, or individual-specific signature. 2. A recent method allows estimating the contribution of periodic patterns to the variance in a movement path. We applied it to 709 individuals from 5 ungulate species, looking for species signatures in the form of seasonal variation in the intensity of circadian patterns. 3. Circadian patterns were commonplace in the movement tracks, but the amount of variance they explained was highly variable among individuals. It increased in intensity during spring and summer, when key resources were spatially segregated, and decreased during winter, when food availability was more uniformly low. Other periodicity-inducing mechanisms supported by our comparison of species- and sex-specific patterns involve young anti-predator behavior, territoriality, and behavioral thermoregulation. 4. Model-based continuous-time movement metrics represent a new avenue for researchers interested in finding individual-, population-, or species-specific signatures in heterogeneous movement databases featuring various study designs and sampling resolutions. However, we observed large amounts of individual variation, so comparative analyses should ideally use both GPS and animal-borne loggers to augment the discriminatory power; and be based on large samples. We briefly outline potential uses of the intensity of circadian patterns as a metric for the study of animal personality and community ecology.",mds,True,findable,204,16,1,1,0,2018-05-11T13:19:14.000Z,2018-05-11T13:19:15.000Z,dryad.dryad,dryad,"Capra ibex,Environmental cycles,ovis musimon,Cervus elaphus,spectral analysis,rupicapra rupicapra,Capreolus capreolus","[{'subject': 'Capra ibex'}, {'subject': 'Environmental cycles'}, {'subject': 'ovis musimon'}, {'subject': 'Cervus elaphus'}, {'subject': 'spectral analysis'}, {'subject': 'rupicapra rupicapra'}, {'subject': 'Capreolus capreolus'}]",['393636 bytes'], +10.5281/zenodo.10428215,Artifacts of the CGO 2024 Paper: EasyTracker: A Python Library for Controlling and Inspecting Program Execution,Zenodo,2023,en,Dataset,Creative Commons Attribution 4.0 International,"This is the archive of the artifacts for the CGO 2024 Paper ""EasyTracker: A Python Library for Controlling and Inspecting Program Execution"" + +The EasyTracker library is an open source project, refer to the Home page and Gitlab repository for up-to-date versions: + + + +Home Page: https://corse.gitlabpages.inria.fr/easytracker + +Repository: https://gitlab.inria.fr/CORSE/easytracker + + +The details of the artifacts generation are described in the paper appendix or in the README.md file included in the main artifacts archive easytracker-artifacts-cgo-2024-v1.2.0.tar.gz. + +Summary of artifacts construction steps (execution in a Docker container): + + + +ensure Docker is installed with docker --version, + +download the artifacts archive easytracker-artifacts-cgo-2024-v1.2.0.tar.gz, + +extract with tar xvzf easytracker-artifacts-cgo-2024-v1.2.0.tar.gz, + +change dir with cd eastracker-artifacts-cgo-2024, + +download the EasyTracker sources archive easytracker-archive-dfe8aa888f.tar.gz, + +extract with tar xvzf easytracker-archive-dfe8aa888f.tar.gz, + +download the docker image docker-image-easytracker-1.2.0.tar, + +load the Docker image with docker load -i docker-image-easytracker-1.2.0.tar, + +generate all artifacts with ./in-docker.sh ./run-all.sh, + +all artifacts are generated in figure-*/ directories, + +refer to the artifacts archive README.md file for more details, or refer to the paper artifacts appendix. + + +Note that this artifacts archive is extracted from the artifacts repository at tag v1.2.0:  https://gitlab.inria.fr/CORSE/easytracker-artifacts-cgo-2024/-/tree/v1.2.0 ",api,True,findable,0,0,0,0,0,2023-12-23T19:10:07.000Z,2023-12-23T19:10:07.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.23994604,Additional file 2 of Determination of different social groups’ level of knowledge about malaria in a multicultural Amazonian cross-border context,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 2: Appendix 2. Factor analyses of multiple-choice variables assessing knowledge of malaria prevention methods,mds,True,findable,0,0,0,0,0,2023-08-20T03:11:03.000Z,2023-08-20T03:11:03.000Z,figshare.ars,otjm,"Biological Sciences not elsewhere classified,Science Policy","[{'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Science Policy'}]",['20317 Bytes'], +10.6084/m9.figshare.22655339.v1,Additional file 1 of ICU admission for solid cancer patients treated with immune checkpoint inhibitors,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Table S1. World Health Organization-Uppsala Monitoring Centre (WHO-UMC) causality categories. Table S2. Diagnosis at ICU admission according to proposed IrAE causality at ICU discharge (n = 110 patients).,mds,True,findable,0,0,0,0,0,2023-04-19T03:54:41.000Z,2023-04-19T03:54:42.000Z,figshare.ars,otjm,"Medicine,Pharmacology,Biotechnology,39999 Chemical Sciences not elsewhere classified,FOS: Chemical sciences,Immunology,FOS: Clinical medicine,Cancer","[{'subject': 'Medicine'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': '39999 Chemical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Chemical sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",['16958 Bytes'], +10.6084/m9.figshare.20080019,Views Evolution 5 Minutes Frequency,figshare,2022,,Dataset,Creative Commons Attribution 4.0 International,"This dataset contains 1934 videos posted between February 2, 2022 and February 16, 2022. For every video it records the amount of views every 5 minutes.",mds,True,findable,0,0,0,0,0,2022-06-16T13:46:14.000Z,2022-06-16T13:46:28.000Z,figshare.ars,otjm,"Applications in physical sciences,Complex physical systems","[{'subject': 'Applications in physical sciences'}, {'subject': 'Complex physical systems'}]",['352821547 Bytes'], +10.6084/m9.figshare.22620031.v1,"Additional file 1 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Genealogical trees of to the 6 consanguineous MMA probands.,mds,True,findable,0,0,0,0,0,2023-04-13T14:39:41.000Z,2023-04-13T14:44:38.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['134635 Bytes'], +10.6084/m9.figshare.c.6797383.v1,Determination of different social groups’ level of knowledge about malaria in a multicultural Amazonian cross-border context,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background A steady decline in the number of cases of malaria was observed in the 2000s in French Guiana. This enabled regional health policies to shift their public health goal from control to elimination. To include inhabitants in this strategy, the main objective of this study was to describe knowledge about malaria, and related attitudes and practices in persons living in the French Guiana border. Methods We conducted a survey in people over 15 years old living in the twelve neighbourhoods of Saint-Georges de l’Oyapock with the highest malaria incidence. It comprised a 147-item questionnaire which collected data on socio-demographic characteristics and included a Knowledge Attitude and Practices survey on malaria. Knowledge-related data were studied using exploratory statistical methods to derive summary variables. A binary variable assessing level of knowledge was proposed and then assessed using exploratory approaches. Results The mean age of the 844 participants was 37.2 years [15.8], the male/female sex ratio was 0.8. In terms of nationality, 485 (57.5%) participants were Brazilian and 352 (41.7%) French. One third (305, 36.1%) spoke Brazilian Portuguese as their native language, 295 (34.9%) the Amerindian language Palikur, 36 (4.3%) French. The symptoms of malaria and prevention means were poorly known by 213 (25.2%) and 378 (44.8%) respondents, respectively. A quarter (206, 24.4%) did not know that malaria can be fatal. Overall, 251 people (29.7%) had an overall poor level of knowledge about malaria. Being under 25 years old, living in a native Amerindian neighbourhood, having an Amerindian mother tongue language, having risk behaviours related to gold mining were significantly associated with a poor level of knowledge. Conclusions This study is the first to describe the poor level of knowledge about malaria in populations living in the malaria endemic border area along the Oyapock river in French Guiana. Results will allow to reinforce, to diversify and to culturally adapt prevention messages and health promotion to increase their effectiveness with a view to quickly reaching the goal of malaria elimination through empowerment.",mds,True,findable,0,0,0,0,0,2023-08-20T03:11:03.000Z,2023-08-20T03:11:04.000Z,figshare.ars,otjm,"Biological Sciences not elsewhere classified,Science Policy","[{'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Science Policy'}]",, +10.5281/zenodo.10022526,Analogue Memristive Devices based on La2NiO4+δ as Synapses for Spiking Neural Networks,Zenodo,2023,,Dataset,Creative Commons Attribution 4.0 International,,api,True,findable,0,0,0,0,0,2023-11-30T09:16:36.000Z,2023-11-30T09:16:36.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.21285665,Additional file 3 of Prognosis of lasso-like penalized Cox models with tumor profiling improves prediction over clinical data alone and benefits from bi-dimensional pre-screening,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 3. A document containing supplementary Figures 1-23 including the corresponding legends.,mds,True,findable,0,0,0,0,0,2022-10-06T07:36:18.000Z,2022-10-06T07:36:18.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Pharmacology,Immunology,FOS: Clinical medicine,69999 Biological Sciences not elsewhere classified,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Cancer","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",['3843262 Bytes'], +10.6084/m9.figshare.24030816,Additional file 1 of Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1. Supplementary tables S1-S6 and supplemtary figures S1-S6.,mds,True,findable,0,0,0,0,0,2023-08-25T03:21:16.000Z,2023-08-25T03:21:17.000Z,figshare.ars,otjm,"Medicine,Biotechnology,Immunology,FOS: Clinical medicine,Biological Sciences not elsewhere classified,Cancer,Science Policy,Mental Health,Infectious Diseases,FOS: Health sciences,Virology","[{'subject': 'Medicine'}, {'subject': 'Biotechnology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Biological Sciences not elsewhere classified'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}, {'subject': 'Mental Health'}, {'subject': 'Infectious Diseases'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Virology'}]",['680816 Bytes'], +10.5061/dryad.n8v4m,Data from: Functional trait differences and trait plasticity mediate biotic resistance to potential plant invaders,Dryad,2018,en,Dataset,Creative Commons Zero v1.0 Universal,"1. Biotic resistance represents an important natural barrier to potential invaders throughout the world, yet the underlying mechanisms that drive such resistance are still debated. In theory, native communities should repel both functionally similar invaders which compete for the same resources, and invaders which possess less competitive traits. However, environmental stress, trade-offs across vital rates and competition-induced plastic trait shifts may modify expected competitive outcomes, thereby influencing invasion dynamics. 2. In order to test these theoretical links between trait distributions and biotic resistance, we performed a mesocosm experiment with 25 non-native ornamental species invading native plant communities. Each non-native species was grown with and without the native community under two watering treatments (regular and reduced). We measured biotic resistance as the difference in performance of non-native individuals grown with and without the community in terms of their survival, growth and reproduction. We quantified overall functional dissimilarity between non-native ornamental individuals and native communities based on the combination of plant height, specific leaf area and seed mass. Then, assuming each of these traits is also potentially linked to competitive ability, we measured the position of non-natives on trait hierarchies. While height is positively correlated with competitive ability for light interception, conservative leaf and seed characteristics provide greater tolerance to competition for other resources. Finally, we quantified plastic trait shifts of non-native individuals induced by competition. 3. Indeed, the native community repelled functionally similar individuals by lowering their survival rate. Simultaneously, shorter ornamental individuals with larger specific leaf areas were less tolerant to biotic resistance from the community across vital rates, although the effect of trait hierarchies often depended on watering conditions. Finally, non-natives responded to competition by shifting their traits. Most importantly, individuals with more competitive traits were able to overcome biotic resistance also through competition-induced plastic trait shifts. 4. Synthesis. Our results highlight that both functional dissimilarity and trait hierarchies mediate biotic resistance to ornamental plant invaders. Nevertheless, environmental stress as well as opposing trends across vital rates are also influential. Furthermore, plastic trait shifts can reinforce potential invaders’ competitive superiority, determining a positive feedback.",mds,True,findable,232,18,1,1,0,2017-12-05T17:25:43.000Z,2017-12-05T17:25:44.000Z,dryad.dryad,dryad,"vital rates,Darwin’s Naturalization Hypothesis,mesocosm experiment,Invasion ecology,fitness differences","[{'subject': 'vital rates'}, {'subject': 'Darwin’s Naturalization Hypothesis'}, {'subject': 'mesocosm experiment'}, {'subject': 'Invasion ecology'}, {'subject': 'fitness differences'}]",['151315 bytes'], +10.5061/dryad.dq444fr,"Data from: Speciation with gene flow: evidence from a complex of alpine butterflies (Coenonympha, Satyridae)",Dryad,2019,en,Dataset,Creative Commons Zero v1.0 Universal,"Until complete reproductive isolation is achieved, the extent of differentiation between two diverging lineages is the result of a dynamic equilibrium between genetic isolation and mixing. This is especially true for hybrid taxa, for which the degree of isolation in regard to their parental species is decisive in their capacity to rise as a new and stable entity. In this work, we explored the past and current patterns of hybridization and divergence within a complex of closely related butterflies in the genus Coenonympha in which two alpine species, C. darwiniana and C. macromma, have been shown to result from hybridization between the also alpine C. gardetta and the lowland C. arcania. By testing alternative scenarios of divergence among species, we show that gene flow has been uninterrupted throughout the speciation process, although leading to different degrees of current genetic isolation between species in contact zones depending on the pair considered. Nonetheless, at broader geographic scale, analyses reveal a clear genetic differentiation between hybrid lineages and their parental species, pointing out to an advanced stage of the hybrid speciation process. Finally, the positive correlation observed between ecological divergence and genetic isolation among these butterflies suggests a potential role for ecological drivers during their speciation processes.",mds,True,findable,187,12,1,1,0,2019-05-17T14:36:53.000Z,2019-05-17T14:36:53.000Z,dryad.dryad,dryad,"Coenonympha,evolutionary history,HINDEX","[{'subject': 'Coenonympha'}, {'subject': 'evolutionary history'}, {'subject': 'HINDEX'}]",['2022537 bytes'], +10.6084/m9.figshare.c.6642960,Phenotype and imaging features associated with APP duplications,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background APP duplication is a rare genetic cause of Alzheimer disease and cerebral amyloid angiopathy (CAA). We aimed to evaluate the phenotypes of APP duplications carriers. Methods Clinical, radiological, and neuropathological features of 43 APP duplication carriers from 24 French families were retrospectively analyzed, and MRI features and cerebrospinal fluid (CSF) biomarkers were compared to 40 APP-negative CAA controls. Results Major neurocognitive disorders were found in 90.2% symptomatic APP duplication carriers, with prominent behavioral impairment in 9.7%. Symptomatic intracerebral hemorrhages were reported in 29.2% and seizures in 51.2%. CSF Aβ42 levels were abnormal in 18/19 patients and 14/19 patients fulfilled MRI radiological criteria for CAA, while only 5 displayed no hemorrhagic features. We found no correlation between CAA radiological signs and duplication size. Compared to CAA controls, APP duplication carriers showed less disseminated cortical superficial siderosis (0% vs 37.5%, p = 0.004 adjusted for the delay between symptoms onset and MRI). Deep microbleeds were found in two APP duplication carriers. In addition to neurofibrillary tangles and senile plaques, CAA was diffuse and severe with thickening of leptomeningeal vessels in all 9 autopsies. Lewy bodies were found in substantia nigra, locus coeruleus, and cortical structures of 2/9 patients, and one presented vascular amyloid deposits in basal ganglia. Discussion Phenotypes associated with APP duplications were heterogeneous with different clinical presentations including dementia, hemorrhage, and seizure and different radiological presentations, even within families. No apparent correlation with duplication size was found. Amyloid burden was severe and widely extended to cerebral vessels as suggested by hemorrhagic features on MRI and neuropathological data, making APP duplication an interesting model of CAA.",mds,True,findable,0,0,0,0,0,2023-05-12T03:40:51.000Z,2023-05-12T03:40:51.000Z,figshare.ars,otjm,"Biochemistry,Medicine,Cell Biology,Neuroscience,Science Policy","[{'subject': 'Biochemistry'}, {'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Neuroscience'}, {'subject': 'Science Policy'}]",, +10.25384/sage.23826552.v1,sj-docx-1-tam-10.1177_17588359231189425 – Supplemental material for Beyond atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma: overall efficacy and safety of tyrosine kinase inhibitors in a real-world setting,SAGE Journals,2023,,Text,Creative Commons Attribution Non Commercial 4.0 International,"Supplemental material, sj-docx-1-tam-10.1177_17588359231189425 for Beyond atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma: overall efficacy and safety of tyrosine kinase inhibitors in a real-world setting by Manon Falette-Puisieux, Jean-Charles Nault, Mohamed Bouattour, Marie Lequoy, Giuliana Amaddeo, Thomas Decaens, Frederic Di Fiore, Sylvain Manfredi, Philippe Merle, Aurore Baron, Christophe Locher, Anna Pellat and Romain Coriat in Therapeutic Advances in Medical Oncology",mds,True,findable,0,0,0,0,0,2023-08-03T00:08:51.000Z,2023-08-03T00:08:52.000Z,figshare.sage,sage,"Oncology and Carcinogenesis not elsewhere classified,Aged Health Care,Pharmacology and Pharmaceutical Sciences not elsewhere classified,Respiratory Diseases","[{'subject': 'Oncology and Carcinogenesis not elsewhere classified'}, {'subject': 'Aged Health Care'}, {'subject': 'Pharmacology and Pharmaceutical Sciences not elsewhere classified'}, {'subject': 'Respiratory Diseases'}]",['13476 Bytes'], +10.5281/zenodo.10419097,"Sliding velocity, water discharge, water pressure, and rainfall time series at Argentière Glacier between 2019 and 2021",Zenodo,2023,,Dataset,Creative Commons Attribution 4.0 International,"Files Description: + +==================================cavitometer_2019-2021.dat:================================== + +Contains 30-min sampled values of recorded sliding velocities at the cavitometer. + +Column 1 = DateColumn 2 = Velocity (mm/hour) + +================================water_discharge_2019-2021.dat:================================ + +Contains 15-min sampled values of recorded water discharge at the glacier outlet. + +Column 1 = DateColumn 2 = Water discharge (m3/s) + +================================water_pressure_2019-2021.dat:================================ + +Contains 30-min sampled values of recorded water pressure at the borehole BH2. + +Column 1 = DateColumn 2 = Water pressure (bar) + +================================rainfall_2019-2021.dat:================================ + +Contains 30-min sampled values of recorded rainfall at the meteo station. + +Column 1 = DateColumn 2 = Rainfall (mm w.eq./hour)",api,True,findable,0,0,0,0,0,2023-12-22T13:03:53.000Z,2023-12-22T13:03:53.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.22625617,"Additional file 4 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 4.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:25.000Z,2023-04-13T18:56:26.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['139801 Bytes'], +10.5061/dryad.s3015,Data from: Extreme climate events counteract the effects of climate and land-use changes in Alpine treelines,Dryad,2017,en,Dataset,Creative Commons Zero v1.0 Universal,"Climate change and extreme events, such as drought, threaten ecosystems world-wide and in particular mountain ecosystems, where species often live at their environmental tolerance limits. In the European Alps, plant communities are also influenced by land-use abandonment leading to woody encroachment of subalpine and alpine grasslands. In this study, we explored how the forest–grassland ecotone of Alpine tree lines will respond to gradual climate warming, drought events and land-use change in terms of forest expansion rates, taxonomic diversity and functional composition. We used a previously validated dynamic vegetation model, FATE-HD, parameterized for plant communities in the Ecrins National Park in the French Alps. Our results showed that intense drought counteracted the forest expansion at higher elevations driven by land-use abandonment and climate change, especially when combined with high drought frequency (occurring every 2 or less than 2 years). Furthermore, intense and frequent drought accelerated the rates of taxonomic change and resulted in overall higher taxonomic spatial heterogeneity of the ecotone than would be expected under gradual climate and land-use changes only. Synthesis and applications. The results from our model show that intense and frequent drought counteracts forest expansion driven by climate and land-use changes in the forest–grassland ecotone of Alpine tree lines. We argue that land-use planning must consider the effects of extreme events, such as drought, as well as climate and land-use changes, since extreme events might interfere with trends predicted under gradual climate warming and agricultural abandonment.",mds,True,findable,264,28,1,1,0,2016-06-28T18:41:06.000Z,2016-06-28T18:41:07.000Z,dryad.dryad,dryad,,,['3287641109 bytes'], +10.6084/m9.figshare.c.6592129.v1,"Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Moyamoya angiopathy (MMA) is a rare cerebrovascular condition leading to stroke. Mutations in 15 genes have been identified in Mendelian forms of MMA, but they explain only a very small proportion of cases. Our aim was to investigate the genetic basis of MMA in consanguineous patients having unaffected parents in order to identify genes involved in autosomal recessive MMA. Methods Exome sequencing (ES) was performed in 6 consecutive consanguineous probands having MMA of unknown etiology. Functional consequences of variants were assessed using western blot and protein 3D structure analyses. Results Causative homozygous variants of NOS3, the gene encoding the endothelial nitric oxide synthase (eNOS), and GUCY1A3, the gene encoding the alpha1 subunit of the soluble guanylate cyclase (sGC) which is the major nitric oxide (NO) receptor in the vascular wall, were identified in 3 of the 6 probands. One NOS3 variant (c.1502 + 1G > C) involves a splice donor site causing a premature termination codon and leads to a total lack of eNOS in endothelial progenitor cells of the affected proband. The other NOS3 variant (c.1942 T > C) is a missense variant located into the flavodoxine reductase domain; it is predicted to be destabilizing and shown to be associated with a reduction of eNOS expression. The GUCY1A3 missense variant (c.1778G > A), located in the catalytic domain of the sGC, is predicted to disrupt the tridimensional structure of this domain and to lead to a loss of function of the enzyme. Both NOS3 mutated probands suffered from an infant-onset and severe MMA associated with posterior cerebral artery steno-occlusive lesions. The GUCY1A3 mutated proband presented an adult-onset MMA associated with an early-onset arterial hypertension and a stenosis of the superior mesenteric artery. None of the 3 probands had achalasia. Conclusions We show for the first time that biallelic loss of function variants in NOS3 is responsible for MMA and that mutations in NOS3 and GUCY1A3 are causing fifty per cent of MMA in consanguineous patients. These data pinpoint the essential role of the NO pathway in MMA pathophysiology.",mds,True,findable,0,0,0,0,0,2023-04-13T14:39:41.000Z,2023-04-13T14:46:27.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.6084/m9.figshare.22620034.v1,"Additional file 2 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 2: 3D structural analysis of the functional consequences of the eNOS p.C648R variant and sGC alpha1 subunit p.R593H variant.,mds,True,findable,0,0,0,0,0,2023-04-13T14:42:15.000Z,2023-04-13T14:44:31.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['36825 Bytes'], +10.6084/m9.figshare.21285662,Additional file 2 of Prognosis of lasso-like penalized Cox models with tumor profiling improves prediction over clinical data alone and benefits from bi-dimensional pre-screening,figshare,2022,,Text,Creative Commons Attribution 4.0 International,Additional file 2. A document containing supplementary Table 1 with TCGA cancer abbreviations.,mds,True,findable,0,0,0,0,0,2022-10-06T07:36:17.000Z,2022-10-06T07:36:17.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Pharmacology,Immunology,FOS: Clinical medicine,69999 Biological Sciences not elsewhere classified,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Cancer","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",['450424 Bytes'], +10.5061/dryad.cjsxksn63,Strong links between plant traits and microbial activities but different abiotic drivers in mountain grasslands,Dryad,2021,en,Dataset,Creative Commons Zero v1.0 Universal,"This dataset contains data and code that support the results in Weil, S.-S., Martinez-Almoyna, C., Piton, G., Renaud, J., Boulangeat, L., Foulquier, A., ... & Thuiller, W. (2021) Strong links between plant traits and microbial activities but different abiotic drivers in mountain grasslands. Journal of Biogeography, 48(11), 2755-2770. We used an extensive plant-soil dataset that covers 14 elevational gradients (between 1500 and 2800 m of elevation) distributed over the whole French Alps to analyse the spatial co-dependencies between the plant and soil compartments. We ran a Graphical Lasso that extracts the direct and indirect linkages between plant functional composition, soil microbial activities, and environmental conditions (local climate and soil properties). Our main results are 1) that plant traits are tightly associated with microbial activities, the former being driven by climate and the latter by soil properties; 2) that the dominance of specific plant traits was more important than their diversity to determine plant-soil linkages; and 3) that soil microbes invested strongly in nutrient acquisition in sites with conservative plant traits and reduced organic matter quality.",mds,True,findable,190,7,0,1,0,2021-07-13T00:11:18.000Z,2021-07-13T00:11:19.000Z,dryad.dryad,dryad,"FOS: Biological sciences,FOS: Biological sciences,graphical lasso,ORCHAMP,partial correlation networks,plant-soil (aboveground-belowground) interactions,soil enzymatic activities","[{'subject': 'FOS: Biological sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'graphical lasso'}, {'subject': 'ORCHAMP'}, {'subject': 'partial correlation networks'}, {'subject': 'plant-soil (aboveground-belowground) interactions'}, {'subject': 'soil enzymatic activities'}]",['24344 bytes'], +10.7914/sn/xq_2020,CHAUVET,International Federation of Digital Seismograph Networks,2020,,Dataset,,3 stations sismob,mds,True,findable,0,0,0,0,0,2020-06-12T17:34:42.000Z,2020-06-12T17:34:44.000Z,iris.iris,iris,,,,['SEED data'] +10.6084/m9.figshare.c.6235037,Prognosis of lasso-like penalized Cox models with tumor profiling improves prediction over clinical data alone and benefits from bi-dimensional pre-screening,figshare,2022,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Prediction of patient survival from tumor molecular ‘-omics’ data is a key step toward personalized medicine. Cox models performed on RNA profiling datasets are popular for clinical outcome predictions. But these models are applied in the context of “high dimensionâ€, as the number p of covariates (gene expressions) greatly exceeds the number n of patients and e of events. Thus, pre-screening together with penalization methods are widely used for dimensional reduction. Methods In the present paper, (i) we benchmark the performance of the lasso penalization and three variants (i.e., ridge, elastic net, adaptive elastic net) on 16 cancers from TCGA after pre-screening, (ii) we propose a bi-dimensional pre-screening procedure based on both gene variability and p-values from single variable Cox models to predict survival, and (iii) we compare our results with iterative sure independence screening (ISIS). Results First, we show that integration of mRNA-seq data with clinical data improves predictions over clinical data alone. Second, our bi-dimensional pre-screening procedure can only improve, in moderation, the C-index and/or the integrated Brier score, while excluding irrelevant genes for prediction. We demonstrate that the different penalization methods reached comparable prediction performances, with slight differences among datasets. Finally, we provide advice in the case of multi-omics data integration. Conclusions Tumor profiles convey more prognostic information than clinical variables such as stage for many cancer subtypes. Lasso and Ridge penalizations perform similarly than Elastic Net penalizations for Cox models in high-dimension. Pre-screening of the top 200 genes in term of single variable Cox model p-values is a practical way to reduce dimension, which may be particularly useful when integrating multi-omics.",mds,True,findable,0,0,0,0,0,2022-10-06T07:36:19.000Z,2022-10-06T07:36:20.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Pharmacology,Immunology,FOS: Clinical medicine,69999 Biological Sciences not elsewhere classified,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Cancer","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Pharmacology'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",, +10.5281/zenodo.10200548,Design and optimization of a Chloride Molten Salt Fast Reactor,Zenodo,2023,en,ConferenceProceeding,Creative Commons Attribution 4.0 International,"This paper presents several studies for the design and optimization of a 3GWth breeder Molten Salt Fast Reactor using chloride salts and the uranium cycle (Cl-MSFR). Results lead to a configuration of 45m3 of NaCl-depUCl3-(spent UOX fuel TRUs)Cl3 for the fuel salt, along with a fertile blanket of 80cm of width filled with NaCl-depUCl3 in which a small amount of spent MOX fuel TRUs is dissolved for spent MOX reuse and proliferation resistance. A reprocessing scheme dedicated to the cleaning of these chloride salts is proposed. Finally, preliminary studies on Cl-MSFR deployment don't show any constraints on matter availability and present a good synergy with PWRs.",api,True,findable,0,0,0,0,0,2023-11-23T11:24:15.000Z,2023-11-23T11:24:15.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.c.6257914.v1,Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery,figshare,2022,,Collection,Creative Commons Attribution 4.0 International,"Abstract Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09–0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains in the range of 50%. Early diagnosis and timely surgical intervention are the cornerstones of modern treatment to reduce the high mortality associated with this entity. The advent of endovascular approaches in parallel with modern imaging techniques is evolving and provides new treatment options. Lastly, a focused multidisciplinary approach based on early diagnosis and individualized treatment is essential. Thus, we believe that updated guidelines from World Society of Emergency Surgery are warranted, in order to provide the most recent and practical recommendations for diagnosis and treatment of AMI.",mds,True,findable,0,0,0,0,0,2022-10-20T06:32:09.000Z,2022-10-20T06:32:09.000Z,figshare.ars,otjm,"Medicine,Genetics,FOS: Biological sciences,Neuroscience,Biotechnology,80699 Information Systems not elsewhere classified,FOS: Computer and information sciences","[{'subject': 'Medicine'}, {'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Neuroscience'}, {'subject': 'Biotechnology'}, {'subject': '80699 Information Systems not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Computer and information sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",, +10.25349/d9vw3d,"Holocene earthquake rupture of the XEOLXELEK–Elk Lake fault in the Greater Victoria area, British Columbia, Canada",Dryad,2023,en,Dataset,Creative Commons Zero v1.0 Universal,"Subduction forearcs are subject to seismic hazard from upper plate faults that are often invisible to instrumental monitoring networks. Identifying active faults in forearcs therefore requires integration of geomorphic, geologic, and paleoseismic data. We demonstrate the utility of these approaches in a highly populated region of Vancouver Island, Canada, by combining lidar remote sensing, historical imagery, field investigations, and shallow geophysical surveys to identify a previously unrecognized active fault, the XEOLXELEK - Elk Lake fault, in the northern Cascadia forearc, ~ 10 km north of the city of Victoria. Lidar-derived bare-earth digital terrain models and historical air photos show a ~ 2.5 m-high scarp along the surface of a Quaternary drumlinoid ridge. Paleoseismic trenching and electrical resistivity tomography surveys across the scarp reveal a single reverse-slip earthquake produced a fault-propagation fold above a blind southwest-dipping fault. Five geologically plausible OxCal models of radiocarbon-dated charcoal from deformed deposits and one colluvial wedge constrain the likely earthquake age to between 4.7 and 2.3 ka (68% confidence interval). Fault-propagation fold modeling indicates ~ 3.2 m of reverse slip on a blind, 50° southwest-dipping fault can reproduce the observed deformation. Fault scaling relations suggest a M 6.1–7.6 earthquake with a 13 to 73 km long surface rupture and 2.3 to 3.2 m of dip-slip may be responsible for the deformation observed in the paleoseismic trench. An earthquake near this magnitude in Greater Victoria could result in major damage, and the results of this study highlight the importance of using both remote sensing and field studies to identify and characterize active faults in forearcs and regions with recent glaciation.",mds,True,findable,220,12,0,1,0,2023-05-20T01:22:09.000Z,2023-05-20T01:22:10.000Z,dryad.dryad,dryad,"FOS: Earth and related environmental sciences,FOS: Earth and related environmental sciences,Paleoseismic trench,Cascadia,Active fault,Vancouver Island,Fault-propagation fold,radiocarbon dates,Seismic Hazard,Electrical resistivity tomography","[{'subject': 'FOS: Earth and related environmental sciences', 'subjectScheme': 'fos'}, {'subject': 'FOS: Earth and related environmental sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Paleoseismic trench'}, {'subject': 'Cascadia'}, {'subject': 'Active fault'}, {'subject': 'Vancouver Island'}, {'subject': 'Fault-propagation fold'}, {'subject': 'radiocarbon dates'}, {'subject': 'Seismic Hazard'}, {'subject': 'Electrical resistivity tomography'}]",['159972 bytes'], +10.5061/dryad.mc50c,Data from: Riders in the sky (islands): using a mega-phylogenetic approach to understand plant species distribution and coexistence at the altitudinal limits of angiosperm plant life,Dryad,2017,en,Dataset,Creative Commons Zero v1.0 Universal,"Aim: Plants occurring on high-alpine summits are generally expected to persist due to adaptations to extreme selective forces caused by the harshest climates where angiosperm life is known to thrive. We assessed the relative effects of this strong environmental filter and of other historical and stochastic factors driving plant community structure in very high-alpine conditions. Location: European Alps, Écrins National Park, France. Methods: Using species occurrence data collected from floristic surveys on 15 summits (2,791–4,102 m a.s.l.) throughout the Écrins range, along with existing molecular sequence data obtained from GenBank, we used a mega-phylogenetic approach to evaluate the phylogenetic structure of high-alpine plant species assemblages. We used three nested species pools and two null models to address the importance of species-specific and species-neutral processes for driving coexistence. Results: Compared with the entire species pool of the study region, alpine summits exhibited a strong signal of phylogenetic clustering. Restricting statistical sampling to environmentally and historically defined species pools reduced the significance of this pattern. However, we could not reject a model that explicitly incorporates neutral colonization and local extinction in shaping community structure for dominant plant orders. Between summits, phylogenetic turnover was generally lower than expected. Environmental drivers did not explain overall phylogenetic patterns, but we found significant geographical and climatic structure in phylogenetic diversity at finer taxonomic scales. Main conclusions: Although we found evidence for strong phylogenetic clustering within alpine summits, we were not able to reject models of species-neutral processes to explain patterns of floristic diversity. Our results suggest that plant community structure in high-alpine regions can also be shaped by neutral processes, and not through the sole action of environmental selection as traditionally assumed for harsh and stressful environments.",mds,True,findable,357,46,1,1,0,2017-07-26T17:14:59.000Z,2017-07-26T17:15:00.000Z,dryad.dryad,dryad,"Spermatophyta,alpine flora,mega-phylogeny","[{'subject': 'Spermatophyta'}, {'subject': 'alpine flora'}, {'subject': 'mega-phylogeny'}]",['1167890 bytes'], +10.5061/dryad.s4q6s,Data from: Genetic diversity in widespread species is not congruent with species richness in alpine plant communities,Dryad,2013,en,Dataset,Creative Commons Zero v1.0 Universal,"The Convention on Biological Diversity (CBD) aims at the conservation of all three levels of biodiversity, i.e. ecosystems, species and genes. Genetic diversity represents evolutionary potential and is important for ecosystem functioning. Unfortunately, genetic diversity in natural populations is hardly considered in conservation strategies because it is difficult to measure and has been hypothesized to co-vary with species richness. This means that species richness is taken as a surrogate of genetic diversity in conservation planning, though their relationship has not been properly evaluated. We tested whether the genetic and species levels of biodiversity co-vary, using a large-scale and multi-species approach. We chose the high-mountain flora of the Alps and the Carpathians as study systems and demonstrate that species richness and genetic diversity are not correlated. Species richness thus cannot act as a surrogate for genetic diversity. Our results have important consequences for implementing the CBD when designing conservation strategies.",mds,True,findable,519,100,1,2,0,2012-09-06T20:49:41.000Z,2012-09-06T20:49:41.000Z,dryad.dryad,dryad,"Arabis alpina L.,Saxifraga stellaris L.,Saxifraga wahlenbergii Ball,Hedysarum hedysaroides Schinz & Thell. s.l.,Androsace obtusifolia All.,Festuca supina (= F. airoides) Schur,Festuca carpathica F. Dietr.,Gentiana nivalis L.,Soldanella pusilla Baum.,Gypsophila repens L.,Festuca versicolor Tausch s.l.,Cerastium uniflorum Clairv.,Loiseleuria procumbens (L.) Desv.,Juncus trifidus L.,Phyteuma betonicifolium Vill. s.l.,Geum reptans L.,Sempervivum montanum L. s.l.,Luzula alpinopilosa (Chaix) Breist.,Sesleria caerulea (L.) Ard.,Carex sempervirens Vill.,Primula minima L.,Hornungia alpina (L.) Appel s.l.,Ranunculus alpestris L. s.l.,Campanula barbata L.,Peucedanum ostruthium (L.) W.D. Koch,Rhododendron myrthifolium Schott & Kotschy,Quaternary,alpine vascular plants,Trifolium alpinum L.,Campanula alpina Jacq.,Phyteuma hemisphaericum L.,Phyteuma confusum A. Kern.,Veronica baumgartenii Roem. & Schult.,Dryas octopetala L.,Geum montanum L.,Carex firma Mygind,Ligusticum mutellinoides (Cr.) Vill.,Hypochaeris uniflora Vill.,Campanula serrata (Kit.) Hendrych,Rhododendron ferrugineum L.,Cirsium spinosissimum (L.) Scop.","[{'subject': 'Arabis alpina L.'}, {'subject': 'Saxifraga stellaris L.'}, {'subject': 'Saxifraga wahlenbergii Ball'}, {'subject': 'Hedysarum hedysaroides Schinz & Thell. s.l.'}, {'subject': 'Androsace obtusifolia All.'}, {'subject': 'Festuca supina (= F. airoides) Schur'}, {'subject': 'Festuca carpathica F. Dietr.'}, {'subject': 'Gentiana nivalis L.'}, {'subject': 'Soldanella pusilla Baum.'}, {'subject': 'Gypsophila repens L.'}, {'subject': 'Festuca versicolor Tausch s.l.'}, {'subject': 'Cerastium uniflorum Clairv.'}, {'subject': 'Loiseleuria procumbens (L.) Desv.'}, {'subject': 'Juncus trifidus L.'}, {'subject': 'Phyteuma betonicifolium Vill. s.l.'}, {'subject': 'Geum reptans L.'}, {'subject': 'Sempervivum montanum L. s.l.'}, {'subject': 'Luzula alpinopilosa (Chaix) Breist.'}, {'subject': 'Sesleria caerulea (L.) Ard.'}, {'subject': 'Carex sempervirens Vill.'}, {'subject': 'Primula minima L.'}, {'subject': 'Hornungia alpina (L.) Appel s.l.'}, {'subject': 'Ranunculus alpestris L. s.l.'}, {'subject': 'Campanula barbata L.'}, {'subject': 'Peucedanum ostruthium (L.) W.D. Koch'}, {'subject': 'Rhododendron myrthifolium Schott & Kotschy'}, {'subject': 'Quaternary'}, {'subject': 'alpine vascular plants'}, {'subject': 'Trifolium alpinum L.'}, {'subject': 'Campanula alpina Jacq.'}, {'subject': 'Phyteuma hemisphaericum L.'}, {'subject': 'Phyteuma confusum A. Kern.'}, {'subject': 'Veronica baumgartenii Roem. & Schult.'}, {'subject': 'Dryas octopetala L.'}, {'subject': 'Geum montanum L.'}, {'subject': 'Carex firma Mygind'}, {'subject': 'Ligusticum mutellinoides (Cr.) Vill.'}, {'subject': 'Hypochaeris uniflora Vill.'}, {'subject': 'Campanula serrata (Kit.) Hendrych'}, {'subject': 'Rhododendron ferrugineum L.'}, {'subject': 'Cirsium spinosissimum (L.) Scop.'}]",['1242012 bytes'], +10.5061/dryad.xksn02vn4,Data for: A novel and enhanced calibration of the tilting weir as a flow measurement structure,Dryad,2023,en,Dataset,Creative Commons Zero v1.0 Universal,"To achieve reliable and equitable water distribution it is necessary to + accurately estimate the volumetric discharge of water flow through rivers + and canals. One such method of accomplishing this is by using hydraulic + structures, such as the tilting weir. This structure not only can be used + to measure the discharge of water on a continuous basis, but also allows + for regulating the water level upstream of the structure. Presently, + tilting weirs are often used to control water levels, but the literature + on their utilization as flow measurement structures has remained sparse. + This study presents a thorough analysis of laboratory experiments on + scaled models of tilting weirs, where the flow depth upstream of the + structure (i.e., head) and the inclination angle are used to calibrate an + equation to estimate the discharge to a high degree of accuracy. + Operational guidelines to ensure minimum uncertainty in measurement are + also given. The data published here include head and discharge + measurements for all experiments conducted, including information on the + experimental location, date, and model dimensions. Publication of this + data is intended to allow other researchers to verify the calibration + procedure laid out in the primary article, and as a comparative dataset + for future calibrations.",mds,True,findable,0,0,0,0,0,2023-12-26T04:45:45.000Z,2023-12-26T04:45:46.000Z,dryad.dryad,dryad,"Discharge,Head,Water management,Civil engineering,FOS: Civil engineering,FOS: Civil engineering","[{'subject': 'Discharge'}, {'subject': 'Head', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}, {'subject': 'Water management', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}, {'subject': 'Civil engineering', 'schemeUri': 'https://github.com/PLOS/plos-thesaurus', 'subjectScheme': 'PLOS Subject Area Thesaurus'}, {'subject': 'FOS: Civil engineering', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'FOS: Civil engineering', 'subjectScheme': 'fos'}]",['23068 bytes'], +10.6084/m9.figshare.c.6590285.v1,"Individual and environmental determinants associated with longer times to access pediatric rheumatology centers for patients with juvenile idiopathic arthritis, a JIR cohort study",figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Despite guidelines, poor access to appropriate care for juvenile idiopathic arthritis (JIA) patients remains a global issue. Prompt referral to a pediatric rheumatology (PR) center and effective care is known to be critical for changing the natural history of the disease and improving long-term prognosis. This project assesses socio-economic factors of delayed referral to a pediatric rheumatologist (PRst) for JIA patients in France and Switzerland within the Juvenile Inflammatory Rheumatism (JIR) Cohort. Methods All patients diagnosed with JIA, presenting at one center of the JIRcohort in France or Switzerland with additional data on referral pathway were included. Patient characteristics at first visit to the PR center, dates of visits to healthcare providers during referral, and parent characteristics were extracted from the JIRcohort database. Results Two hundred fifty children were included. The overall median time to first PR assessment was 2.4 months [1.3; 6.9] and ranged widely across the JIA subtypes, from 1.4 months [0.6; 3.8] for children with systemic juvenile idiopathic arthritis (sJIA) to 5.3 months [2.0; 19.1] for children with enthesitis-related arthritis (ERA). A diagnosis of ERA and an appointment with an orthopedist during the referral pathway were significantly associated with a longer time before the first PR visit (hazard ratio HR 0.50 [95% CI: 0.29; 0.84]) and HR 0.68 [95% CI: 0.49; 0.93], respectively) in multivariable analysis. Having a mother with a post-graduate educational attainment level was tendentially associated with a shorter time before the first PR visit, (HR 1.32 [95% CI: 0.99; 1.78]). Conclusions Time to first PRst visit was most often short compared to other studies and close to the British recommendations. However, this time remained too long for many patients. We observed no social inequities in access to a PRst, but we show the need to improve effective pathway and access to a PR center for JIA patients.",mds,True,findable,0,0,0,0,0,2023-04-13T13:55:20.000Z,2023-04-13T13:55:20.000Z,figshare.ars,otjm,"Medicine,Biotechnology,Ecology,FOS: Biological sciences,Immunology,FOS: Clinical medicine,Cancer,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Biotechnology'}, {'subject': 'Ecology'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': 'Science Policy'}]",, +10.5061/dryad.hmgqnk9f6,Resistance-recovery tradeoff of soil microbial communities under altered rain regimes: An experimental test across European agroecosystems,Dryad,2020,en,Dataset,Creative Commons Zero v1.0 Universal,"With the increased occurrence of climate extremes, there is an urgent need to better understand how management strategies affect the capacity of the soil microbial community to maintain its ecosystem functions (e.g. nutrient cycling). To address this issue, intact monoliths were extracted from conventional and ecological managed grasslands in three countries across Europe and exposed under common air condition (temperature and moisture) to one of three altered rain regimes (dry, wet and intermittent wet/dry) as compared to a normal regime. Subsequently, we compared the resistance and recovery of the soil microbial biomass, potential enzyme activities and community composition. The microbial community composition differed with soil management and rain regimes. Soil microbial biomass increased from the wetter to the dryer rain regime, paralleling an increase of available carbon and nutrients, suggesting low sensitivity to soil moisture reduction but nutritional limitations of soil microbes. Conversely, enzyme activities decreased with all altered rain regimes. Resistance and recovery (considering absolute distance between normal and altered rain regime) of the microbial communities depended on soil management. Conventional-intensive management showed higher resistance of two fundamental properties for nutrient cycling (i.e. bacterial biomass and extracellular enzyme activities) yet associated with more important changes in microbial community composition. This suggests an internal community reorganization promoting biomass and activity resistance. Conversely, under ecological management bacterial biomass and enzyme activities showed better recovery capacity, whereas no or very low recovery of these properties was observed under conventional management. These management effects were consistent across the three altered rain regimes investigated, indicating common factors controlling microbial communities’ response to different climate-related stresses. Synthesis and applications: Our study provides experimental evidence for an important trade-off for agro-ecosystem management between i.) stabilizing nutrient cycling potential during an altered rain regime period at the expense of very low recovery capacity and potential long term effect (conventional sites) and ii.) promoting the capacity of the microbial community to recover its functional potential after the end of the stress (ecological sites). Thus management based on ecologically sound principles may be the best option to sustain long-term soil functioning under climate change.",mds,True,findable,169,21,0,0,0,2020-10-02T18:42:57.000Z,2020-10-02T18:42:59.000Z,dryad.dryad,dryad,"copiotrophs,extracellular enzyme,oligotrophs,PLFA,trait","[{'subject': 'copiotrophs'}, {'subject': 'extracellular enzyme'}, {'subject': 'oligotrophs'}, {'subject': 'PLFA'}, {'subject': 'trait'}]",['539373 bytes'], +10.48380/2gzr-9q70,Mineralogical evidence for Quaternary serpentinization in the New-Caledonian ophiolite: Implication for the low-temperature genesis of H2- and CH4-bearing alkaline fluids,Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV),2023,en,Text,,"<p>H<sub>2</sub>-bearing fluids (pH 10 – 12) issued in alkaline springs found in several ophiolitic complexes worldwide are believed to result from the alteration of ultramafic rocks by infiltration of meteoric waters. The mineralogical fingerprint of the reactive percolation of such an alkaline fluid is revealed by veinlet mineralization occurring in the New Caledonian ophiolite (Massif du Sud). In two localities separated by <strong>~</strong> 15<strong> </strong>km (Georges Pile and GR2H mines), late veins in a partially serpentinized peridotite contain magnetite crystals younger than 2 Ma as inferred from (U-Th)/He geochronometry. While the serpentinite host at Georges Pile is largely overprinted by lateritic weathering, primary parageneses are preserved at GR2H. There, magnetite occurs along with dolomite and Fe-poor lizardite as filling in millimeter sized veins cross-cutting the mesh texture of the partially serpentinized dunite. Temperature of the aqueous fluid from which the vein material precipitated is estimated to be ~95°C from <em>in situ</em> δ<sup>18</sup>O data on the magnetite-dolomite pair, indicating a low-temperature alteration process. Thermochemical calculation shows that this aqueous fluid was alkaline and most likely H<sub>2</sub>-bearing. Chemically, it strongly resembles waters that are issued today in H<sub>2</sub> and CH<sub>4</sub> – bearing (hyper)alkaline springs of the Massif du Sud. δ<sup>13</sup>C isotopic composition of dolomite is exceptionally high, between 7.1 and up to 17.3 ‰ and is interpreted as evidence for low-temperature methanogenesis.</p> +",api,True,findable,0,0,0,0,0,2023-12-11T20:33:23.000Z,2023-12-11T20:33:23.000Z,mcdy.dohrmi,mcdy,,,, +10.18150/damcb2,"Dataset from the analysis of dielectric, mechanical and calorimetric response of phosphonium ionic liquids with DCA, TCM and SCN anions",RepOD,2023,,Dataset,,"This dataset contains raw dielectric, mechanical and calorimetric data published in the article entitled “Self-Assembled Nanostructures in Aprotic Ionic Liquids Facilitate Charge Transport at Elevated Pressure†in ACS Applied Materials & Interfaces (https://pubs.acs.org/doi/10.1021/acsami.3c08606). The included data consists of results collected for three quaternary phosphonium ionic liquids with hydrophobic [P666,14 ] + cation and anions: thiocyanate [SCN] − , dicyanamide [DCA] − and tricyanomethanide [TCM] − . Raw data correspond to figures published in the main article and supporting information file.",mds,True,findable,0,0,0,0,0,2023-09-20T11:58:53.000Z,2023-09-20T12:01:51.000Z,tib.repod,repod,,,, +10.14470/ks178126,META-WT,GFZ Data Services,2023,en,Dataset,"embargoed access,Creative Commons Attribution 4.0 International","The META-WT project was designed to perform a 4-weeks seismic experiment in Germany with a dense seismic array of ~400 three-component geophones that covered (1) a 2.5km x 2.5km wind farm area in Brandenburg, Germany, with almost 200 wind turbines (WTs) and a well-studied subsurface structure and (2) a 20-km long radial line from the center of the wind farm with one geophone every half-kilometer. The objective was to capture the spatio-temporal seismic wave-field signature of the wind farm from continuous recordings of ambient noise. Due to the dense interstation distance and proposed geometry the experiment allowed for analyzing both small-scale wave field characteristics at an unprecedented spatial resolution and the longer distance radiation pattern of the wind farm. Waveform data is available from the GEOFON data centre, under network code XF, and is embargoed until Jan 2025.",mds,True,findable,0,0,0,0,0,2023-04-25T11:09:17.000Z,2023-04-25T11:09:18.000Z,tib.gfz,gfz,"Broadband seismic waveforms,Seismic monitoring,EARTH SCIENCE > SOLID EARTH > TECTONICS > EARTHQUAKES,In Situ/Laboratory Instruments > Magnetic/Motion Sensors > Seismometers,In Situ Land-based Platforms > GEOPHYSICAL STATIONS/NETWORKS,In Situ Land-based Platforms > GEOPHYSICAL STATIONS/NETWORKS > SEISMOLOGICAL STATIONS","[{'subject': 'Broadband seismic waveforms'}, {'subject': 'Seismic monitoring'}, {'lang': 'en', 'subject': 'EARTH SCIENCE > SOLID EARTH > TECTONICS > EARTHQUAKES', 'schemeUri': 'http://gcmdservices.gsfc.nasa.gov/kms/concepts/concept_scheme/sciencekeywords', 'subjectScheme': 'NASA/GCMD Earth Science Keywords'}, {'lang': 'en', 'subject': 'In Situ/Laboratory Instruments > Magnetic/Motion Sensors > Seismometers', 'schemeUri': 'http://gcmdservices.gsfc.nasa.gov/kms/concepts/concept_scheme/sciencekeywords', 'subjectScheme': 'GCMD Instruments'}, {'lang': 'en', 'subject': 'In Situ Land-based Platforms > GEOPHYSICAL STATIONS/NETWORKS', 'schemeUri': 'http://gcmdservices.gsfc.nasa.gov/kms/concepts/concept_scheme/sciencekeywords', 'subjectScheme': 'GCMD Platforms'}, {'lang': 'en', 'subject': 'In Situ Land-based Platforms > GEOPHYSICAL STATIONS/NETWORKS > SEISMOLOGICAL STATIONS', 'schemeUri': 'http://gcmdservices.gsfc.nasa.gov/kms/concepts/concept_scheme/sciencekeywords', 'subjectScheme': 'GCMD Platforms'}]",['~400G'],"['.mseed', 'XML']" +10.5281/zenodo.10022527,Analogue Memristive Devices based on La2NiO4+δ as Synapses for Spiking Neural Networks,Zenodo,2023,,Dataset,Creative Commons Attribution 4.0 International,,api,True,findable,0,0,0,0,0,2023-11-30T09:16:35.000Z,2023-11-30T09:16:35.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.22625614,"Additional file 3 of A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppression in kidney transplant recipients in the first year after transplantation: TTVguideIT",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 3.,mds,True,findable,0,0,0,0,0,2023-04-13T18:56:28.000Z,2023-04-13T18:56:29.000Z,figshare.ars,otjm,"Immunology,FOS: Clinical medicine","[{'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['359400 Bytes'], +10.5061/dryad.jdfn2z378,"Persistence of arctic-alpine flora during 24,000 years of environmental change in the Polar Urals",Dryad,2019,en,Dataset,Creative Commons Zero v1.0 Universal,"Plants adapted to extreme conditions can be at high risk from climate change; arctic-alpine plants, in particular, could “run out of space†as they are out-competed by expansion of woody vegetation. Mountain regions could potentially provide safe sites for arctic-alpine plants in a warmer climate, but empirical evidence is fragmentary. Here we present a 24,000-year record of species persistence based on sedimentary ancient DNA (sedaDNA) from Lake Bolshoye Shchuchye (Polar Urals). We provide robust evidence of long-term persistence of arctic-alpine plants through large-magnitude climate changes but document a decline in their diversity during a past expansion of woody vegetation. Nevertheless, most of the plants that were present during the last glacial interval, including all of the arctic-alpines, are still found in the region today. This underlines the conservation significance of mountain landscapes via their provision of a range of habitats that confer resilience to climate change, particularly for arctic-alpine taxa.",mds,True,findable,289,38,0,0,0,2019-12-17T15:15:14.000Z,2019-12-17T15:15:15.000Z,dryad.dryad,dryad,,,['6768200622 bytes'], +10.5281/zenodo.10441454,Maps of the diversity and distribution of Raunkiær's life forms in European vegetation,Zenodo,2023,en,Dataset,Creative Commons Attribution 4.0 International,"This repository contains raster files (TIF format) with a 50 km × 50 km resolution (over UTM grid EPSG:32633), showcasing the diversity and distribution of Raunkiær’s life forms in European vegetation. The maps are based on two key metrics: (i) the proportion (%) of species within each life form and (ii) the diversity of life forms, including richness and evenness. + +To generate these maps, we averaged plot-level metric values across a comprehensive dataset comprising 546,501 vegetation plots sourced from the European Vegetation Archive (EVA; Project 163; https://euroveg.org). These plots cover diverse habitats, including 173,190 forests, 260,884 grasslands, 52,517 scrubs, and 59,910 wetlands. + +The maps encompass the entire dataset, offering a visualization of the geographical distribution patterns of life forms across Europe. Additionally, we created habitat-specific maps by subsetting the dataset to explore unique patterns within each habitat type (forest, grassland, scrub, and wetland). + +Furthermore, we generated additional maps based on standardised effect sizes (SES) of diversity metrics. Through 500 species identity shuffles without replacement, specific to each habitat type, we examined the deviations from random expectations. SES values outside the range of -1.96 to 1.96 indicate significantly lower or higher metric values than expected at random, respectively. + + + + + + +Folder name +Description of TIF raster values + + +full.div +Mean richness and evenness of life forms across all habitat types + + +full.mean.rel.prop +Mean proportion of each life form across all habitat types + + +habitat.div +Mean richness and evenness of life forms across separate habitat types (forest, grassland, scrub, and wetland) + + +habitat.mean.rel.prop +Mean proportion of each life form across separate habitat types (forest, grassland, scrub, and wetland) + + +SES.full.div +Mean richness and evenness of life forms across all habitat types measured with standardized effect sizes (SES) + + +SES.full.mean.rel.prop +Mean proportion of each life form across all habitat types measured with standardized effect sizes (SES) + + +SES.habitat.div +Mean richness and evenness of life forms across separate habitat types (forest, grassland, scrub, and wetland) measured with standardized effect sizes (SES) + + +SES.habitat.mean.rel.prop +Mean proportion of each life form across separate habitat types (forest, grassland, scrub, and wetland) measured with standardized effect sizes (SES) + + + + +Additional information is available in our publication:Midolo, G., Axmanová, I., DivÃÅ¡ek, J., DÅ™evojan, P., Lososová, Z., VeÄeÅ™a, M., Karger, D. N., Thuiller, W., Bruelheide, H., Aćić, S., Attorre, F., Biurrun, I., Boch, S., Bonari, G., ÄŒarni, A., Chiarucci, A., ĆuÅ¡terevska, R., Dengler, J., Dziuba, T., Garbolino, E., Jandt, U., Lenoir, J., Marcenò, C., RÅ«siņa, S., Å ibÃk, J., Å kvorc, Ž., StanÄić, Z., StaniÅ¡ić-VujaÄić, M., Svenning, J. C., Swacha, G., Vassilev, K., & Chytrý, M. (2024) Diversity and distribution of Raunkiær’s life forms in European vegetation. Journal of Vegetation Science. Accepted on the 10th of December 2023",api,True,findable,0,0,0,0,0,2023-12-29T13:53:18.000Z,2023-12-29T13:53:19.000Z,cern.zenodo,cern,"annual plant,growth form,plant functional trait,plant lifespan,species richness,tree,shrub,therophyte,phanerophyte,geophyte,hydrophyte,hemicryptophyte,chamaephyte,plant evenness,plant species richness","[{'subject': 'annual plant'}, {'subject': 'growth form'}, {'subject': 'plant functional trait'}, {'subject': 'plant lifespan'}, {'subject': 'species richness'}, {'subject': 'tree'}, {'subject': 'shrub'}, {'subject': 'therophyte'}, {'subject': 'phanerophyte'}, {'subject': 'geophyte'}, {'subject': 'hydrophyte'}, {'subject': 'hemicryptophyte'}, {'subject': 'chamaephyte'}, {'subject': 'plant evenness'}, {'subject': 'plant species richness'}]",, +10.6084/m9.figshare.22620040.v1,"Additional file 4 of Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy",figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 4: NOS3 homozygous splice variant in M084 and NOS3 homozygous missense variant in M035.,mds,True,findable,0,0,0,0,0,2023-04-13T14:39:41.000Z,2023-04-13T14:43:26.000Z,figshare.ars,otjm,"Genetics,FOS: Biological sciences","[{'subject': 'Genetics'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['286190 Bytes'], +10.6084/m9.figshare.22807638,Additional file 1 of Phenotype and imaging features associated with APP duplications,figshare,2023,,Image,Creative Commons Attribution 4.0 International,Additional file 1: Supp Figure 1. MRI scans of two APP duplication carriers showing deep microbleeds (orange arrows). A: EXT_814 carrying a 5.7Mb duplication and B: EXT_1516 carrying a 0.95Mb duplication.,mds,True,findable,0,0,0,0,0,2023-05-12T03:40:49.000Z,2023-05-12T03:40:49.000Z,figshare.ars,otjm,"Biochemistry,Medicine,Cell Biology,Neuroscience,Science Policy","[{'subject': 'Biochemistry'}, {'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Neuroscience'}, {'subject': 'Science Policy'}]",['568868 Bytes'], +10.6084/m9.figshare.c.6424523.v2,Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃,Optica Publishing Group,2023,,Collection,Creative Commons Attribution 4.0 International,"By performing Bidirectionnal Reflectance Distribution Function (BRDF) measurements, we have identified back-scattering as the main phenomena involved in the appearance of dry nano-crystallized powders. We introduce an analytical and physically-based BRDF model that relies on the enhanced back-scattering theory to accurately reproduce BRDF measurements. These experimental data were performed on optically thick layers of dry powders with various grains’ morphologies. Our results are significantly better than the ones obtained with previous models. Our model has been validated against the BRDF measurements of multiple synthesized nano-crystallized and mono-disperse 𛼠− Fe2O3 hematite powders. Finally, we discuss the ability of our model to be extended to other materials or more complex powder morphologies.",mds,True,findable,0,0,0,0,0,2023-09-01T15:04:45.000Z,2023-09-01T15:04:45.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],, +10.6084/m9.figshare.c.6606032.v1,ICU admission for solid cancer patients treated with immune checkpoint inhibitors,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Immune checkpoint inhibitors (ICI) have revolutionized the management of cancer. They can induce immune-related adverse events (irAE) leading to intensive care unit (ICU) admission. We aimed to describe irAEs for ICU admissions in solid cancer patients treated with ICIs. Methods This prospective multicenter study was conducted in France and Belgium. Adult patients with solid tumor and treated with systemic ICIs within the last 6 months, requiring non-programmed ICU admission were included. Patients admitted for microbiologically documented sepsis were excluded. Imputability of irAEs in ICU admissions was described according to the WHO-UMC classification system at ICU admission and at ICU discharge. The use of immunosuppressant treatment was reported. Results 115 patients were eligible. Solid tumor was mainly lung cancer (n = 76, 66%) and melanoma (n = 18, 16%). They were mainly treated with an anti-PD-(L)1 alone (n = 110, 96%). Main ICU admission reasons were acute respiratory failure (n = 66, 57%), colitis (n = 14, 13%), and cardiovascular disease (n = 13, 11%). ICU admission was considered “likely†associated with irAE for 48% (n = 55) of patients. Factors independently associated with irAE were a good ECOG performance status (PS) (ECOG-PS of 0 or 1 vs. ECOG-PS of 2–3, odds ratio [OR] = 6.34, 95% confidence interval [95% CI] 2.13–18.90, and OR = 3.66, 95% CI 1.33–10.03, respectively), and a history of irAE (OR = 3.28, 95% CI 1.19–9.01). Steroids were prescribed for 41/55 (75%) patients with ICU admission “likely†related to irAE. Three patients were subsequently treated with immunosuppressants. Conclusion IrAEs accounted for half of ICU admissions in cancer patients receiving ICIs. They could be treated with steroids. Identifying the imputability of irAEs in ICU admissions remains a challenge.",mds,True,findable,0,0,0,0,0,2023-04-19T03:54:42.000Z,2023-04-19T03:54:43.000Z,figshare.ars,otjm,"Medicine,Pharmacology,Biotechnology,39999 Chemical Sciences not elsewhere classified,FOS: Chemical sciences,Immunology,FOS: Clinical medicine,Cancer","[{'subject': 'Medicine'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': '39999 Chemical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Chemical sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",, +10.6084/m9.figshare.c.6627379.v1,"Multiple trauma in pregnant women: injury assessment, fetal radiation exposure and mortality. A multicentre observational study",figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Fetal radiation exposure in pregnant women with trauma is a concern. The purpose of this study was to evaluate fetal radiation exposure with regard to the type of injury assessment performed. Methods It is a multicentre observational study. The cohort study included all pregnant women suspected of severe traumatic injury in the participating centres of a national trauma research network. The primary outcome was the cumulative radiation dose (mGy) received by the fetus with respect to the type of injury assessment initiated by the physician in charge of the pregnant patient. Secondary outcomes were maternal and fetal morbi-mortality, the incidence of haemorrhagic shock and the physicians’ imaging assessment with consideration of their medical specialty. Results Fifty-four pregnant women were admitted for potential major trauma between September 2011 and December 2019 in the 21 participating centres. The median gestational age was 22 weeks [12–30]. 78% of women (n = 42) underwent WBCT. The remaining patients underwent radiographs, ultrasound or selective CT scans based on clinical examination. The median fetal radiation doses were 38 mGy [23–63] and 0 mGy [0–1]. Maternal mortality (6%) was lower than fetal mortality (17%). Two women (out of 3 maternal deaths) and 7 fetuses (out of 9 fetal deaths) died within the first 24 h following trauma. Conclusions Immediate WBCT for initial injury assessment in pregnant women with trauma was associated with a fetal radiation dose below the 100 mGy threshold. Among the selected population with either a stable status with a moderate and nonthreatening injury pattern or isolated penetrating trauma, a selective strategy seemed safe in experienced centres.",mds,True,findable,0,0,0,0,0,2023-05-03T03:19:17.000Z,2023-05-03T03:19:18.000Z,figshare.ars,otjm,"Medicine,Cell Biology,Biotechnology,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,19999 Mathematical Sciences not elsewhere classified,FOS: Mathematics,Developmental Biology,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Cell Biology'}, {'subject': 'Biotechnology'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '19999 Mathematical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Mathematics', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Developmental Biology'}, {'subject': 'Science Policy'}]",, +10.5061/dryad.kc7h9,Data from: Evaluating the impact of domestication and captivity on the horse gut microbiome,Dryad,2018,en,Dataset,Creative Commons Zero v1.0 Universal,"The mammal gut microbiome, which includes host microbes and their respective genes, is now recognized as an essential second genome that provides critical functions to the host. In humans, studies have revealed that lifestyle strongly influences the composition and diversity of the gastrointestinal microbiome. We hypothesized that these trends in humans may be paralleled in mammals subjected to anthropogenic forces such as domestication and captivity, in which diets and natural life histories are often greatly modified. We investigated fecal microbiomes of Przewalski’s horse (PH; Equus ferus przewalskii), the only horses alive today not successfully domesticated by humans, and herded, domestic horse (E. f. caballus) living in adjacent natural grasslands. We discovered PH fecal microbiomes hosted a distinct and more diverse community of bacteria compared to domestic horses, which is likely partly explained by different plant diets as revealed by trnL maker data. Within the PH population, four individuals were born in captivity in European zoos and hosted a strikingly low diversity of fecal microbiota compared to individuals born in natural reserves in France and Mongolia. These results suggest that anthropogenic forces can dramatically reshape equid gastrointestinal microbiomes, which has broader implications for the conservation management of endangered mammals.",mds,True,findable,372,55,0,1,0,2017-10-31T14:59:05.000Z,2017-10-31T14:59:06.000Z,dryad.dryad,dryad,"horse,Przewalski horse,trnL marker,Modern,Przewalski’s horse,Holocene","[{'subject': 'horse'}, {'subject': 'Przewalski horse'}, {'subject': 'trnL marker'}, {'subject': 'Modern'}, {'subject': 'Przewalski’s horse'}, {'subject': 'Holocene'}]",['13602031 bytes'], +10.6084/m9.figshare.23816832.v2,Supplementary document for Dry powders reflectance model based on enhanced back-scattering: case of hematite α-Feâ‚‚O₃ - 6551122.pdf,Optica Publishing Group,2023,,Text,Creative Commons Attribution 4.0 International,Supplemental document.,mds,True,findable,0,0,0,0,0,2023-09-01T15:04:45.000Z,2023-09-01T15:04:45.000Z,figshare.ars,otjm,Uncategorized,[{'subject': 'Uncategorized'}],['11379174 Bytes'], +10.6084/m9.figshare.22655339,Additional file 1 of ICU admission for solid cancer patients treated with immune checkpoint inhibitors,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1: Table S1. World Health Organization-Uppsala Monitoring Centre (WHO-UMC) causality categories. Table S2. Diagnosis at ICU admission according to proposed IrAE causality at ICU discharge (n = 110 patients).,mds,True,findable,0,0,0,0,0,2023-04-19T03:54:41.000Z,2023-04-19T03:54:42.000Z,figshare.ars,otjm,"Medicine,Pharmacology,Biotechnology,39999 Chemical Sciences not elsewhere classified,FOS: Chemical sciences,Immunology,FOS: Clinical medicine,Cancer","[{'subject': 'Medicine'}, {'subject': 'Pharmacology'}, {'subject': 'Biotechnology'}, {'subject': '39999 Chemical Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Chemical sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}]",['16958 Bytes'], +10.25384/sage.c.6772590,Beyond atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma: overall efficacy and safety of tyrosine kinase inhibitors in a real-world setting,SAGE Journals,2023,,Collection,Creative Commons Attribution 4.0 International,"Background:In patients with advanced hepatocellular carcinoma (HCC) progressing after atezolizumab and bevacizumab, the optimal therapeutic sequence is still unclear and no second-line agent has proven its efficacy.Objectives:The aim of this retrospective multicenter real-world cohort study was to provide an evaluation of the efficacy and safety of the use of second-line tyrosine kinase inhibitors (TKIs) in this population.Methods:All patients with advanced HCC, treated in first-line setting by atezolizumab–bevacizumab, and who received at least one dose of treatment with TKI were included in this study. All the data were retrospectively collected from medical records. The primary outcome was progression-free survival (PFS). Secondary outcomes were overall survival (OS), overall global survival (OGS), and safety. A total of 82 patients were included in this study.Results:Patients were assigned to the regorafenib group (<i>n</i> = 29, 35.4%) or other TKI (sorafenib <i>n</i> = 41, lenvatinib <i>n</i> = 8, or cabozantinib <i>n</i> = 4) group (<i>n</i> = 53). PFS was not significantly different between the two groups [2.6 <i>versus</i> 2.8 months, HR 1.07 (95% CI: 0.61–1.86), <i>p</i> = 0.818]. Median PFS rates were 2.6, 4.4, and 2.8 months in sorafenib-, lenvatinib-, and cabozantinib group, respectively. OS was statistically different between the regorafenib group and other TKI group [15.8 <i>versus</i> 7.0 months, HR 0.40 (95% CI: 0.20–0.79), <i>p</i> = 0.023]. When adjusting on confounding factors, there was still a difference in OS favoring the regorafenib group (adjusted hazard ratio 0.35, <i>p</i> = 0.019). OGS of patients who received regorafenib was improved compared to other TKI [18.6 <i>versus</i> 15.0 months, HR 0.42 (95% CI: 0.22–0.84), <i>p</i> = 0.036]. Twenty percent of patients had grade 3 and none had grade 4 or 5 adverse events. In patients who experienced disease progression and fit for a third-line treatment, 80% and 50% received cabozantinib in regorafenib group and other TKI group, respectively.Conclusion:Efficacy of any TKI in the second-line setting was not affected by atezolizumab–bevacizumab treatment as first-line therapy. The safety profile in the second-line setting was consistent with the results shown in pivotal studies. PFS rates of patients were similar, regardless of TKI type. Regorafenib was associated with better OS and OGS rates compared to other TKI. These data need to be confirmed in prospective comparative studies.",mds,True,findable,0,0,0,0,0,2023-08-03T00:08:51.000Z,2023-08-03T00:08:52.000Z,figshare.sage,sage,"Oncology and Carcinogenesis not elsewhere classified,Aged Health Care,Pharmacology and Pharmaceutical Sciences not elsewhere classified,Respiratory Diseases","[{'subject': 'Oncology and Carcinogenesis not elsewhere classified'}, {'subject': 'Aged Health Care'}, {'subject': 'Pharmacology and Pharmaceutical Sciences not elsewhere classified'}, {'subject': 'Respiratory Diseases'}]",, +10.6084/m9.figshare.22877643.v1,Additional file 1 of Digital undergraduate medical education and patient and carer involvement: a rapid systematic review of current practice,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Additional file 1. Sample Search Strategy (Ovid MEDLINE).,mds,True,findable,0,0,0,0,0,2023-05-17T03:24:26.000Z,2023-05-17T03:24:27.000Z,figshare.ars,otjm,"Medicine,Science Policy,69999 Biological Sciences not elsewhere classified,FOS: Biological sciences,111714 Mental Health,FOS: Health sciences","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}, {'subject': '69999 Biological Sciences not elsewhere classified', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Biological sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}]",['14508 Bytes'], +10.5281/zenodo.10229534,Research compendium to reproduce analyses and figures of the article: Interspecific interactions influence bird population responses to global changes by Gaüzère et al. submitted in Ecology Letters,Zenodo,2023,,Software,Creative Commons Attribution 4.0 International,"Research compendium to reproduce analyses and figures of the article: +_Interspecific interactions influence bird population responses to global changes_ +by Gaüzère _et al._ submitted in _Ecology Letters_ + +#' Compendium authors +#' @author Pierre Gaüzère, \email{pierre.gauzere@@gmail.com}, + +## General + + This repository is structured as follow: + + - `data/`: contains data required to reproduce figures and tables + - `analyses/`: contains scripts organized sequentially. prepare data -> run model -> vizualize model outputs -> .. + - `outputs/`: follows the structure of analyses. Contains intermediate numeric + results used to produce the figures + - `figures_tables/`: Contains the figures of the paper + +## Figures & tables + + Figures will be stored in `figures_tables/`. + Tables will be stored in `outputs/`.",api,True,findable,0,0,0,0,0,2023-11-30T15:03:09.000Z,2023-11-30T15:03:09.000Z,cern.zenodo,cern,,,, +10.6084/m9.figshare.c.6575881,Procalcitonin to reduce exposure to antibiotics and individualise treatment in hospitalised old patients with pneumonia: a randomised study,figshare,2023,,Collection,Creative Commons Attribution 4.0 International,"Abstract Background Treating pneumonia in old patients remains challenging for clinicians. Moreover, bacterial antimicrobial resistance is a major public health threat. Objective The PROPAGE study evaluated the interest of a strategy using serial measurements of procalcitonin (PCT) to reduce the duration of antibiotic therapy in old patients with pneumonia. Methods PROPAGE took place from Dec.-2013 to Jun.-2016 in eight French geriatric units. It was a prospective, comparative, randomised, open-label study involving old patients (≥ 80 years) who had initiated antibiotic treatment for pneumonia in the previous 48 h. PCT was monitored in all patients and two decision-making PCT-based algorithms guided antibiotic therapy in patients from the PCT group. Results 107 patients were randomised (PCT, n = 50; Control, n = 57). Antibiotic therapy exposure was reduced in the PCT group as compared to the Control group (median duration of antibiotic therapy, 8 vs. 10 days [rank-test, p = 0.001]; antibiotic persistence rates on Days 6 and 8, 54% and 44% vs. 91% and 72%) and no significant difference was found in recovery rate (84% vs. 89.5%; Pearson Chi² test, p = 0.402). Conclusion Although, the superiority of the strategy was not tested using a composite criterion combining antibiotic therapy duration and recovery rate was not tested due to the small sample size, the present study showed that monitoring associated with PCT-guided algorithm could help shorten antibiotic treatment duration in the very old patients without detrimental effects. Measuring PCT levels between Day 4 and Day 6 could be helpful when making the decision regarding antibiotic discontinuation. Trial registration NCT02173613. This study was first registered on 25/06/2014.",mds,True,findable,0,0,0,0,0,2023-04-13T09:42:57.000Z,2023-04-13T09:42:57.000Z,figshare.ars,otjm,"Space Science,Medicine,Immunology,FOS: Clinical medicine,Cancer,111714 Mental Health,FOS: Health sciences,110309 Infectious Diseases","[{'subject': 'Space Science'}, {'subject': 'Medicine'}, {'subject': 'Immunology'}, {'subject': 'FOS: Clinical medicine', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': 'Cancer'}, {'subject': '111714 Mental Health', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}, {'subject': 'FOS: Health sciences', 'schemeUri': 'http://www.oecd.org/science/inno/38235147.pdf', 'subjectScheme': 'Fields of Science and Technology (FOS)'}, {'subject': '110309 Infectious Diseases', 'schemeUri': 'http://www.abs.gov.au/ausstats/abs@.nsf/0/6BB427AB9696C225CA2574180004463E', 'subjectScheme': 'FOR'}]",, +10.6084/m9.figshare.24091564,Additional file 1 of Survey of adolescents’ needs and parents’ views on sexual health in juvenile idiopathic arthritis,figshare,2023,,Text,Creative Commons Attribution 4.0 International,Supplementary Material 1,mds,True,findable,0,0,0,0,0,2023-09-06T17:23:03.000Z,2023-09-06T17:23:03.000Z,figshare.ars,otjm,"Medicine,Science Policy","[{'subject': 'Medicine'}, {'subject': 'Science Policy'}]",['309248 Bytes'], +10.5061/dryad.vx0k6djp4,Data from : Vacant yet invasible niches in forest community assembly,Dryad,2020,en,Dataset,Creative Commons Zero v1.0 Universal,"It is controversial whether communities are saturated with species, or have vacant niches. The prevalence of vacant niches and the processes likely to promote their existence are poorly known. We used a processâ€based forest gapâ€model to simulate plant community dynamics in 11 sites along a climatic gradient across central Europe. We then used hypervolume analyses to study the existence of vacant niches (seen as empty volumes in the trait space of local species pools and communities), and we tested for the effect of abiotic (environmental filtering) and biotic (competition) processes on the functional hypervolumes along the climatic gradient. Last, we performed invasion simulations to assess the invasibility of detected vacant niches. Our results suggest that empty volumes in trait space are common, can arise from both abiotic and biotic processes, and are more likely in cold climates. We also showed that most vacant niches are invasible. 4. Synthesis: Our work supports the view that niche space is unsaturated, and that many viable ecological strategies are absent from these forest communities.",mds,True,findable,172,23,1,1,0,2020-06-22T22:40:00.000Z,2020-06-22T22:40:02.000Z,dryad.dryad,dryad,,,['19201663 bytes'], diff --git a/run-all-codes.py b/run-all-codes.py index 851e8e9..e122930 100644 --- a/run-all-codes.py +++ b/run-all-codes.py @@ -1,27 +1,54 @@ import subprocess -def execute_python_file(fila_name): +""" +0. collect DOIs +1. concatenate & enrich with dataCite API +2. produce graphs +""" + +def run_py_file(file_name, parent_folder): """ excute a py program """ try : ## cwd py programs path - subprocess.run(['python', fila_name], cwd= "0-collect-data") + subprocess.run(['python', file_name], cwd= parent_folder) except FileNotFoundError: - print(f"Error: The file '{fila_name}' does not exist.") + print(f"error: the file '{file_name}' does not exist") -file_names = [ +# ______0______ collect DOIs +collec_dois_prgm = [ "zenodo.py", "nakala.py", "datacite.py", "rdg.py" ] -for file in file_names : - execute_python_file(file) + +#to depug : run a=only one script +#collec_dois_prgm = ["rdg.py"] +[run_py_file(file, "0-collect-data") for file in collec_dois_prgm] +# exit() + + + +# ______1______ Concatenate and enrich DOIs w DataCite +run_py_file("concatenate-enrich-dois.py", "1-enrich-with-datacite") + + + +# ______2______ Produce graphics + +produce_graph_prgm = [ + "hist-quantity-by-year.py", + "pie-datacite-client.py", + "pie-data-type.py" +] + +[run_py_file(file, "2-produce-graph") for file in produce_graph_prgm] + -# execute_python_file(file_names[1]) -- GitLab